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CompletedNCT00304785Updated Oct 24, 2007

Latanoprost Versus Fotil

A Phase 4 interventional study of latanoprost 0.005% and Fotil in Open-Angle Glaucoma and Ocular Hypertension, sponsored by Pharmaceutical Research Network. Completed at 5 sites in Poland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2007-10-24.

Sponsored by Pharmaceutical Research Network · Phase 4, Interventional, and Treatment

Phase
Phase 4
Study type
Interventional
Enrollment
36
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

To compare the intraocular pressure effect and safety of latanoprost 0.005% given every evening versus PTFC given twice daily.

02

Conditions studied

  • Open-Angle Glaucoma
  • Ocular Hypertension
03

In context

Glaucoma, Open-Angle

943 studies on the registry are indexed under Glaucoma, Open-Angle; 118 are open to participants now.

This study's planned enrollment of 36 is below the median of 80 across 710 interventional studies indexed under Glaucoma, Open-Angle.

Browse Glaucoma, Open-Angle studies →

Lead sponsor

Pharmaceutical Research Network is the lead sponsor of 6 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • adults with primary open-angle or pigment dispersion glaucoma, or ocular hypertension
  • untreated intraocular pressure should be between 24-36 mm Hg inclusive
  • visual acuity should be 5/50 or better in both eyes

Exclusion criteria

Exclusion Criteria:

  • presence of exfoliation syndrome or exfoliation glaucoma
  • contraindications to study medications
  • any anticipated change in systemic hypotensive therapy
05

Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Double
Enrollment
36 participants (estimated)

Interventions

06

Study locations

5 sites
  • Gabinety Okulistyczne
    Bydgoszcz, PL-85-670, Poland
  • Kierownik Kliniki Okulistycznej Akademii Medycznej
    Poznan, PL-61-848, Poland
  • Instytut Jaskry
    Warsaw, 00415, Poland
  • Katdra Klinika Okulityki Akademii Medycznej w Warszawie
    Warsaw, 02-005, Poland
  • Ordynator Oddziału Okulistycznego Międzyleski Szpital Specjalistyczny
    Warsaw, PL-04-749, Poland
07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 24, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00304785
Lead sponsor
Pharmaceutical Research Network
First posted
Mar 20, 2006
Start date
May 2005
Completion
Oct 2007
Last update
Oct 24, 2007

Study contacts

William C. Stewart, MD
study director · Pharmaceutical Research Network, LLC
Józef Kałużny, Professor
principal investigator · Gabinety Okulistyczne
Krystyna Pecold, Professor
principal investigator · Kierownik Kliniki Okulistycznej Akademii Medycznej
Roman Sobecki, Dr. n.med.
principal investigator · Ordynator Oddziału Okulistycznego Międzyleski Szpital Specjalistyczny
Krystyna Czechowisz-Janicka, Professor
principal investigator · Instytut Jaskry
Dariusz Kecik, Professor
principal investigator · Katdra Klinika Okulityki Akademii Medycznej w Warszawie
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2007. You cannot join it, but the record below documents what was studied.

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Studies of the drug tested here: Latanoprost

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