A Phase 4 interventional study of Garlic Oil Macerate in Healthy, sponsored by Albany Medical College. Suspended at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2007-03-20.
Sponsored by Albany Medical College · Phase 4, Interventional, and Treatment
This research will investigate the effect of garlic oil extract when added to daily diet on inflammatory mediators and blood clotting activation.
To investigate the pharmacokinetics of one of the garlic oil macerate, Ajoene, the anti-inflammatory effect of garlic oil macerate on the pro-inflammatory transcription factor NF-kB, it's activating proteins, including IkB, IkB Kinases a and B (IKKa and IKKB) and the pro-inflammatory NF-kB-regulated proteins, c-reactive protein (CRP), tumor necrosis factor-alpha (TNF-a), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), matrix metalloproteinase-9 (MMP-9), plasminogen activated protein-1 (PAI-1)and the effect of garlic oil macerate intake on platelet activation in normal subjects.
Albany Medical College is the lead sponsor of 80 studies on the registry; 14 are open to participants now.
Of its 17 completed or terminated interventional studies of FDA-regulated products, 3 (18%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
1. To examine the pharmacokinetics of the garlic oil macerate.
2. To examine the effect of garlic oil macerate on inflammatory mechanisms at the cellular and molecular level.
This study is suspended, as verified in Mar 2007. You cannot join it, but the record below documents what was studied.
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Albany Medical College