CClinicalTrials.gg
TerminatedNCT00273507Updated Sep 18, 2009

Neoadjuvant Chemotherapy in Non Small Cell Lung Cancer (NSCLC) Stages IB, IIA, IIB, and IIIA/T3

A Phase 3 interventional study of Carboplatin and Paclitaxel in Non-small Cell Lung Cancer, sponsored by Rigshospitalet, Denmark. Terminated at 1 site in Denmark. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2009-09-18.

Sponsored by Rigshospitalet, Denmark · Phase 3, Interventional, and Treatment

Phase
Phase 3
Study type
Interventional
Enrollment
270
Allocation
Randomized
Ages
18 Years to 75 Years
Sex
All
01

Study summary

Randomised trial of chemotherapy or not before surgery in early resectable stages of NSCLC (IB, IIA, IIB, and IIIA/N2).

Read the detailed description

Randomisation between 3 courses of neoadjuvant Carboplatin plus Paclitaxel or no chemotherapy before surgery.

02

Conditions studied

  • Non-small Cell Lung Cancer

Keywords

  • Non-small cell lung cancer
  • neoadjuvant
  • resection
03

In context

Lung Neoplasms

7,243 studies on the registry are indexed under Lung Neoplasms; 1,557 are open to participants now.

This study's enrollment of 270 is above the median of 60 across 5,295 interventional studies indexed under Lung Neoplasms.

Browse Lung Neoplasms studies →

Lead sponsor

Rigshospitalet, Denmark is the lead sponsor of 1,017 studies on the registry; 183 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • NSCLC
  • Stages IB, IIA, IIB, IIIA/T3
  • Lung function test allowing surgery
  • Age 18-75 years

Exclusion criteria

Exclusion Criteria:

  • Poor lung function
  • Performance status 3-4
  • Mediastinal lymph node involvement
05

Study design

Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
270 participants

Interventions

  • DrugCarboplatin and Paclitaxel
06

What researchers measure

Primary outcomes

  1. Survival

Secondary outcomes

  1. Time to progression

  2. Complete resection rate

07

Study locations

1 site
  • Dept. Oncology, Rigshospitalet
    Copenhagen, 2100, Denmark
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 18, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00273507
Lead sponsor
Rigshospitalet, Denmark
First posted
Jan 9, 2006
Start date
Jan 1998
Completion
Jan 2006
Last update
Sep 18, 2009

Study contacts

Jens B. Sorensen, MD
study chair · Dept. Oncology, Rigshospitalet
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Sep 2009. You cannot join it, but the record below documents what was studied.

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