A Phase 4 interventional study of Penicillin versus cefuroxim per os in Streptococcal Infections, sponsored by University Children's Hospital Basel. Terminated at 1 site in Switzerland. Open to participants aged 1 Year to 16 Years. Per ClinicalTrials.gov, last updated 2007-01-17.
Sponsored by University Children's Hospital Basel · Phase 4, Interventional, and Treatment
The goal of the study is to investigate, which of two antibiotic treatments - oral penicillin for 10 days or oral cefuroxim for 7 days - is more successful for patients (1-16 years of age) with perianal dermatitis caused by group A beta-hemolytic streptococci.
The goal of the study is to investigate, which of two antibiotic treatments - oral penicillin for 10 days or oral cefuroxim for 7 days - is more successful for patients (1-16 years of age) with perianal dermatitis caused by group A beta-hemolytic streptococci (GABHS). Diagnosis is based on positive perianal culture for GABHS. Informed consent will be obtained.
The study will be performed in the region of Basel, Switzerland, in private practices of pediatricians, general practitioners, and selected pediatric dermatologists as well as in the out-patient departments of the University Children's Hospital Basel and the department for dermatology of the University of Basel.
Patients (or their parents) will fill in a daily diary on signs and symptoms of disease; furthermore, clinical investigations (inspection of the site of infection) will be performed on enrollment (Day 1), Day 3, and at the end of treatment (Day 10).
155 studies on the registry are indexed under Streptococcal Infections; 15 are open to participants now.
This study's enrollment of 194 is below the median of 250 across 105 interventional studies indexed under Streptococcal Infections.
Browse Streptococcal Infections studies →University Children's Hospital Basel is the lead sponsor of 27 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Resolving signs and symptoms of perianal dermatitis
microbiological cure (= negative culture for GABHS) at end of treatment
This study is terminated, as verified in Jan 2007. You cannot join it, but the record below documents what was studied.
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University Children's Hospital Basel