An interventional study of Resistance Training and Sedentary in Sarcopenia and Cardiovascular Disease, sponsored by Texas A&M University. Completed at 1 site in United States. Open to participants aged 50 Years to 69 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-09-29.
Sponsored by Texas A&M University · Not applicable, Interventional, and Prevention
The purpose of this study is to examine the effect of dietary cholesterol administered as whole egg or egg white (control)on muscle mass gain with resistance training in a young old population of men and women (age 50-69). It is hypothesized that dietary cholesterol will be significantly associated to muscle mass gain.
The primary objective of this proposal is to have 36 men and women (age 50-69) perform 12 weeks of resistance exercise training for the purpose of inducing skeletal muscle hypertrophy. These individuals will consume either 0, 1, or 3 whole eggs per day in a double-blind design to test the hypothesis that dietary cholesterol is essential for skeletal muscle hypertrophy. If so proven, this will confirm a very strong association between dietary cholesterol and hypertrophy observed in a previous study of 51 men and women (age 60-69). The current proposal is using a randomized double-blind, placebo controlled design to provide the most conclusive evidence that dietary cholesterol plays an essential role in skeletal muscle hypertrophy.
The secondary objective of this proposal is to test the hypothesis that increased dietary cholesterol consumption in the context of an exercise program does not alter blood cholesterol concentrations or other cardiovascular risk factors.
1,208 studies on the registry are indexed under Sarcopenia; 402 are open to participants now.
This study's enrollment of 36 is below the median of 60 across 775 interventional studies indexed under Sarcopenia.
Browse Sarcopenia studies →Texas A&M University is the lead sponsor of 123 studies on the registry; 23 are open to participants now.
Of its 7 completed or terminated interventional studies of FDA-regulated products, 2 (29%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
\< 200 mg/day dietary cholesterol, resistance training, sedentary
Behavioral: Resistance Training · Behavioral: Sedentary
400 mg/day dietary cholesterol, resistance training, sedentary
Behavioral: Resistance Training · Behavioral: Sedentary
800 mg/day dietary cholesterol, resistance training, sedentary
Behavioral: Resistance Training · Behavioral: Sedentary
12 weeks, 3 times a week whole body resistance training
Absence of physical activity
Primary: Strength and muscle gain (DEXA)
Time frame: after 12 weeks of resistance training
Secondary: Blood lipids, inflammatory markers, blood pressure
Time frame: after 12 weeks of resistance training
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Texas A&M University