CClinicalTrials.gg
CompletedNCT00260130Updated May 30, 2013

Food Rheology and Feeding in Lean and Obese Humans

An interventional study of food in fluid form and food in solid form in Obesity, Overweight and Diabetes, sponsored by Purdue University. Completed at 1 site in United States. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-05-30.

Sponsored by Purdue University · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
34
Allocation
Randomized
Ages
18 Years to 40 Years
Sex
All
01

Study summary

The 2010 National Health Objectives call for a reduction in the prevalence of obesity. The marked recent increase in overweight and obesity prevalence implicates behavioral factors in the etiology of the epidemic. The present proposal hypothesizes the trend is attributal, in part, to increasing consumption of energy-yeilding beverages since they are a significant and increasing source of dietarty energy and they elicit weaker appetitive and dietary responses than solid foods.

Read the detailed description

Three human studies are propsed to more fully characterized attributes of liquids and solids that may account for the differential appetitive responses they elicit, potential contributory mechanisms as well as the dietary implications of their consumption. Study 1 will contrast the acute effects of fluid and solid foods varying in macronutrient content on satiation, satiety and feeding. Study 2 will determine if the pattern of fluid and solid ingestion influences satiety and feeding by monitoring appetitive and dietary responses to energy and macronutrient matched fluid and solid loads ingested as meal components or between meal snacks. To better assess the clinical implications ofdiets incorpprating liquid or solid supplements. Study 3 will entail chronic ingestion of matched energy yeilding fluid or solid loads with concurrent measurement of appetite, dietary intake, energy expenditureand body weight/composition.

02

Conditions studied

  • Obesity
  • Overweight
  • Diabetes

Browse trials for

Keywords

  • obesity
  • food intake
  • human
  • energy balance
  • beverage
03

In context

Overweight

3,670 studies on the registry are indexed under Overweight; 849 are open to participants now.

This study's planned enrollment of 34 is below the median of 73 across 3,175 interventional studies indexed under Overweight.

Browse Overweight studies →

Lead sponsor

Purdue University is the lead sponsor of 168 studies on the registry; 23 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • BMI 18-23 or 27-35
  • weight stable
  • constant habitual activity pattern
  • low fruit/vegetable consumer
  • non-restrained eater

Exclusion criteria

Exclusion Criteria:

  • diabetic
  • taking medication known to influence appetite
05

Study design

Phase
Not applicable
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
34 participants (estimated)

Study arms

  • Active comparator
    1

    Consuming fruit and vegetable juice

    Other: food in fluid form

  • Active comparator
    2

    Consuming whole fruits and vegetables

    Other: food in solid form

Interventions

  • Otherfood in fluid form

    dietary intake of fluid forms of vegetables

  • Otherfood in solid form

    dietary intake of solid forms of vegetables

06

What researchers measure

Primary outcomes

  1. satiation and satiety on liquid verses solid foods with concurrent measurements of appetite, dietary intake, energy expenditure and body weight/composition.

    Time frame: 8 weeks

Secondary outcomes

  1. cephalic phase testing at week 8

    Time frame: 30 minutes

07

Study locations

1 site
  • Purdue University
    West Lafayette, Indiana 47906, United States
08

References and documents

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 30, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00260130
Lead sponsor
Purdue University
Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Responsible party
Richard Mattes (Prof. Foods and Nutrition, Purdue University) — Principal investigator
First posted
Dec 1, 2005
Start date
Feb 2005
Primary completion
Dec 2007
Completion
Jul 2009
Last update
May 30, 2013

Study contacts

Richard D Mattes, MPH, PhD, RD
principal investigator · Purdue University
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2013. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion