A Phase 1 interventional study of Benadryl versus Placebo in Gallbladder Disease, Gallstones and Pancreatitis, sponsored by University of Rochester. Withdrawn. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-09-18.
Sponsored by University of Rochester · Phase 1, Interventional, and Diagnostic
The purpose of the study is to determine if adding Benadryl improves sedation for patients scheduled to undergo ERCP or EUS procedures.
The usual sedatives used for endoscopy are meperidine (Demerol) and midazolam (Versed). Benadryl (Diphenhydramine) is often used in addition to these medications in an effort to improve sedation. There is little published information regarding the use of diphenhydramine in conscious sedation. It is recognized that certain patients have features that predict difficult sedation such as prescription sedative use or heavy alcohol use. In addition, prolonged procedures like ERCP and EUS require higher doses of sedatives. Diphenhydramine may improve the quality of sedation in patients undergoing endoscopic retrograde cholangio-pancreatography (ERCP) or endoscopic ultrasound (EUS) procedures. You are being asked to participate because you are already scheduled to undergo one of these procedures.
752 studies on the registry are indexed under Pancreatitis; 181 are open to participants now.
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Of its 56 completed or terminated interventional studies of FDA-regulated products, 44 (79%) have results posted.
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Exclusion Criteria:
Recovery score
Quality of sedation
No study locations are listed for this record.
This study is withdrawn, as verified in Sep 2015. You cannot join it, but the record below documents what was studied.
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