An interventional study of uvulopalatopharyngoplasty with or without sutures in Obstructive Sleep Apnea, sponsored by Virginia Commonwealth University. Completed at 1 site in United States. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2012-06-21.
Sponsored by Virginia Commonwealth University · Not applicable, Interventional, and Treatment
In this study we will examine whether suture repair of the palate, or roof of mouth, has any effect on results of palate surgery performed for treatment of obstructive sleep apnea.
Uvulopalatopharyngoplasty, or UPPP, is the most common surgical procedure performed for the treatment of obstructive sleep apnea. The procedure involves removal of redundant tissue from the lower palate (roof of mouth), including the uvula, and then suturing the cut edges of the remaining tissue together. However it is frequently noted by surgeons that sutures placed in the roof of the mouth do not stay intact. Also, in standard tonsillectomy, which involves removal of the tonsils and thus creation of a wound near the palate, no suturing is used, which does not seem to affect how the area heals. Previous studies have shown no significant differences in complication rates, post-operative pain, or symptom outcomes in patients undergoing tonsillectomy either with or without suture repair of the tonsillectomy wound. In this study we will examine whether suture repair following UPPP has any effect on post-operative pain, healing, or treatment success in terms of symptom resolution or post-operative sleep study results.
1,422 studies on the registry are indexed under Apnea; 159 are open to participants now.
This study's enrollment of 16 is below the median of 50 across 965 interventional studies indexed under Apnea.
Browse Apnea studies →Virginia Commonwealth University is the lead sponsor of 641 studies on the registry; 82 are open to participants now.
Of its 88 completed or terminated interventional studies of FDA-regulated products, 62 (70%) have results posted.
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Exclusion Criteria:
suture palate after resection
Procedure: uvulopalatopharyngoplasty with or without sutures
suture one side of palate afer resection
Procedure: uvulopalatopharyngoplasty with or without sutures
no sutures in palate after resection
Procedure: uvulopalatopharyngoplasty with or without sutures
standard UPPP
sleep study result at 3-6 months; symptom changes at 3-6 months; pain at 0-3 weeks; post-operative complications at any time; post-operative anatomic result/appearance at 3-6 months
Time frame: 6-12mo
Operative time
Time frame: immediate
Procedure cost
Time frame: immediate
This study is completed, as verified in Jun 2012. You cannot join it, but the record below documents what was studied.
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Virginia Commonwealth University