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CompletedNCT00185120Updated Jan 18, 2012

Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Calcium Channel Blocker

A Phase 4 interventional study of Olmesartan medoxomil and Hydroclorothiazide in Hypertension, sponsored by Daiichi Sankyo. Completed at 20 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2012-01-18.

Sponsored by Daiichi Sankyo · Phase 4, Interventional, and Treatment

Phase
Phase 4
Study type
Interventional
Enrollment
152
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

A comparison of 2 different combinations of high blood pressure medications to treat hypertension

02

Conditions studied

  • Hypertension

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Keywords

  • Hypertension
  • angiotensin receptor blocker
  • calcium channel blocker
  • angiotensin converting enzyme inhibitor hydroclorothiazide
03

In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.

This study's enrollment of 152 is above the median of 90 across 4,995 interventional studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

Daiichi Sankyo is the lead sponsor of 316 studies on the registry; 35 are open to participants now.

Of its 51 completed or terminated interventional studies of FDA-regulated products, 38 (75%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Greater than 18 years of age
  • Patients with high blood pressure

Exclusion criteria

Exclusion Criteria:

  • Hypertensive encephalopathy, stroke or transient ischemic attack within the past 6 months
  • History of myocardial infarction, percutaneous transluminal coronary revascularization, coronary artery bypass graft, and/or unstable angina pectoris within the past 6 months
  • Type 1 diabetes mellitus
05

Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
152 participants

Interventions

  • DrugOlmesartan medoxomil
  • DrugHydroclorothiazide
  • DrugBenazepril
  • DrugAmlodipine
06

What researchers measure

Primary outcomes

  1. Change in systolic blood pressure from the start of the study

Secondary outcomes

  1. Change in diastolic blood pressure from the start of the study

  2. Percent of patients who achieve target blood pressure goals

07

Study locations

20 sites
  • Mobile, Alabama 36693, United States
  • Memorial Research Medical Center
    Long Beach, California 90806, United States
  • National Research Institute
    Los Angeles, California 90057, United States
  • Clinical Trials Research
    Roseville, California 95661, United States
  • Apex Research Institute
    Santa Ana, California 92705, United States
  • Orange County Research Center
    Tustin, California 92780, United States
  • Westlake Medical Center
    Westlake Village, California 91361, United States
  • Clinical Research of South Florida
    Coral Gables, Florida 33134, United States
  • The Greater Fort Lauderdale Heart Group Research
    Fort lauderdale, Florida 33308, United States
  • SFBC International
    Miami, Florida 33142, United States
  • CLIRECO, Inc.
    Tamarac, Florida 33321, United States
  • Midwest Institute for Clinical Research
    Indianapolis, Indiana 46260, United States
  • Heartland Research Associates
    Wichita, Kansas 67207, United States
  • Androscoggin Cardiology Research
    Auburn, Maine 04210, United States
  • Internal Medicine Associates of Charlotte
    Charlotte, North Carolina 28211, United States
  • Piedmont Medical Research Associates
    Winston-salem, North Carolina 27103, United States
  • The Lindner Clinical Trial Center
    Cincinnati, Ohio 45319, United States
  • Omega Medical Research
    Warwick, Rhode Island 02886, United States
  • Volunteer Research Group, University of Tennessee Med. Ctr.
    Knoxville,, Tennessee 37920, United States
  • Punzi Medical Center
    Carrollton, Texas 75006, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 18, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00185120
Lead sponsor
Daiichi Sankyo
Responsible party
Sponsor
First posted
Sep 16, 2005
Start date
Sep 2005
Primary completion
Sep 2006
Completion
Sep 2006
Last update
Jan 18, 2012
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jan 2012. You cannot join it, but the record below documents what was studied.

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