An observational study in Von Willebrand Disease, sponsored by The University of Texas Health Science Center, Houston. Terminated at 1 site in United States. Open to female participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2013-05-06.
Sponsored by The University of Texas Health Science Center, Houston · Observational
The primary objective of this study is to describe characteristics and trends for thrombin generation (TG) and thromboelastography (TEG) at 4 time points during the menstrual cycle.
We propose that TG and TEG will be more sensitive than traditional coagulation assays to detect physiologic variation in hemostasis, fibrinolysis, and platelet activation throughout the menstrual cycle. We expect that TG and TEG will better discriminate patients with vWD than traditional coagulation studies during the menstrual cycle. In this study we plan to measure TG and TEG in healthy women and women with von Willebrand's disorder during four phases of the menstrual cycle. We will compare specific measurements of endogenous thrombin generation potential from the TG and fibrinolysis and platelet activation from the TEG with standard measures of coagulation, fibrinolysis, and platelet activation markers during the menstrual cycle.
63 studies on the registry are indexed under Von Willebrand Diseases; 4 are open to participants now.
This study's enrollment of 20 is below the median of 102 across 31 observational studies indexed under Von Willebrand Diseases.
Browse Von Willebrand Diseases studies →The University of Texas Health Science Center, Houston is the lead sponsor of 880 studies on the registry; 209 are open to participants now.
Of its 170 completed or terminated interventional studies of FDA-regulated products, 140 (82%) have results posted.
Counted across the registry records on this site, refreshed daily.
Females with a diagnosis of von Willebrand Disease
Exclusion Criteria:
Endogenous Thrombin Potential
Comparison of 4 values collected during 4 phases of through the menstrual cycle
Time frame: 4 weeks
This study is terminated, as verified in May 2013. You cannot join it, but the record below documents what was studied.
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The University of Texas Health Science Center, Houston