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CompletedNCT00173615Updated Jan 19, 2009

Extracorporeal Membrane Oxygenation Effect in Prolonged Cardiopulmonary Resuscitation

An observational study in Cardiopulmonary Resuscitation, Cardiac Arrest and Ventricular Tachycardia, sponsored by National Taiwan University Hospital. Completed at 1 site in Taiwan. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2009-01-19.

Sponsored by National Taiwan University Hospital · Observational

Study type
Observational
Enrollment
100
Ages
18 Years to 85 Years
Sex
All
01

Study summary

Analysis of the patients' data who were rescued with extracorporeal membrane oxygenation and without ECMO. The survival rate and the weaning rate were analyzed to see the effect of ECMO on the prolonged CPR.

02

Conditions studied

  • Cardiopulmonary Resuscitation
  • Cardiac Arrest
  • Ventricular Tachycardia
  • Ventricular Fibrillation

Keywords

  • ECMO
  • CPR
03

In context

Heart Arrest

984 studies on the registry are indexed under Heart Arrest; 227 are open to participants now.

This study's enrollment of 100 is below the median of 196 across 394 observational studies indexed under Heart Arrest.

Browse Heart Arrest studies →

Lead sponsor

National Taiwan University Hospital is the lead sponsor of 2,608 studies on the registry; 573 are open to participants now.

Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.

Browse National Taiwan University Hospital studies →

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • CPR > 10 min without return of spontaneous circulation

Exclusion criteria

Exclusion Criteria:

  • CPR with traumatic origin unless bleeding was under control, previous irreversible brain damage, terminal status of malignancy, and the age over 75 years. For the patients with post-cardiotomy shock requiring ECLS in the operating theater because of an inability of weaning from cardiopulmonary bypass, they were excluded as well from this ECPR cohort since they did not receive cardiac massage. The patients that had signed "Do-Not-Resuscitate" (DNR) consent were also excluded from ECLS deployment.
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Study design

Enrollment
100 participants

Interventions

  • ProcedureExtracorporeal membrane oxygenation
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Study locations

1 site
  • National Taiwan University Hospital
    Taipei, 100, Taiwan
07

References and documents

Publications

  • KOUWENHOVEN WB, JUDE JR, KNICKERBOCKER GG. Closed-chest cardiac massage. JAMA. 1960 Jul 9;173:1064-7. doi: 10.1001/jama.1960.03020280004002. No abstract available. PubMed 14411374 ↗
  • Eisenberg MS, Mengert TJ. Cardiac resuscitation. N Engl J Med. 2001 Apr 26;344(17):1304-13. doi: 10.1056/NEJM200104263441707. No abstract available. PubMed 11320390 ↗
  • Bedell SE, Delbanco TL, Cook EF, Epstein FH. Survival after cardiopulmonary resuscitation in the hospital. N Engl J Med. 1983 Sep 8;309(10):569-76. doi: 10.1056/NEJM198309083091001. PubMed 6877286 ↗
  • Cooper S, Janghorbani M, Cooper G. A decade of in-hospital resuscitation: outcomes and prediction of survival? Resuscitation. 2006 Feb;68(2):231-7. doi: 10.1016/j.resuscitation.2005.06.012. Epub 2005 Dec 1. PubMed 16325314 ↗
  • Weil MH, Fries M. In-hospital cardiac arrest. Crit Care Med. 2005 Dec;33(12):2825-30. doi: 10.1097/01.ccm.0000191265.20007.9d. PubMed 16352966 ↗
  • Chen YS, Chao A, Yu HY, Ko WJ, Wu IH, Chen RJ, Huang SC, Lin FY, Wang SS. Analysis and results of prolonged resuscitation in cardiac arrest patients rescued by extracorporeal membrane oxygenation. J Am Coll Cardiol. 2003 Jan 15;41(2):197-203. doi: 10.1016/s0735-1097(02)02716-x. PubMed 12535808 ↗
  • Cummins RO, Chamberlain D, Hazinski MF, Nadkarni V, Kloeck W, Kramer E, Becker L, Robertson C, Koster R, Zaritsky A, Bossaert L, Ornato JP, Callanan V, Allen M, Steen P, Connolly B, Sanders A, Idris A, Cobbe S. Recommended guidelines for reviewing, reporting, and conducting research on in-hospital resuscitation: the in-hospital 'Utstein style'. American Heart Association. Circulation. 1997 Apr 15;95(8):2213-39. doi: 10.1161/01.cir.95.8.2213. No abstract available. PubMed 9133537 ↗
  • Tunstall-Pedoe H, Bailey L, Chamberlain DA, Marsden AK, Ward ME, Zideman DA. Survey of 3765 cardiopulmonary resuscitations in British hospitals (the BRESUS Study): methods and overall results. BMJ. 1992 May 23;304(6838):1347-51. doi: 10.1136/bmj.304.6838.1347. PubMed 1611332 ↗
  • Vincent JL, de Mendonca A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Crit Care Med. 1998 Nov;26(11):1793-800. doi: 10.1097/00003246-199811000-00016. PubMed 9824069 ↗
  • Chen YS, Lin JW, Yu HY, Ko WJ, Jerng JS, Chang WT, Chen WJ, Huang SC, Chi NH, Wang CH, Chen LC, Tsai PR, Wang SS, Hwang JJ, Lin FY. Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: an observational study and propensity analysis. Lancet. 2008 Aug 16;372(9638):554-61. doi: 10.1016/S0140-6736(08)60958-7. Epub 2008 Jul 4. PubMed 18603291 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 19, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00173615
Lead sponsor
National Taiwan University Hospital
First posted
Sep 15, 2005
Start date
Apr 1996
Completion
Dec 2006
Last update
Jan 19, 2009

Study contacts

Yih-Sharng Chen, MD, PhD
principal investigator · National Taiwan University Hospital
View the source record on ClinicalTrials.gov ↗

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