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CompletedNCT00160212Updated Jan 30, 2009

Study to Evaluate the Efficacy and Safety of SLV306 in Subjects With Hypertension

A Phase 2 interventional study of Daglutril in Hypertension, sponsored by Solvay Pharmaceuticals. Completed at 130 sites in 11 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2009-01-30.

Sponsored by Solvay Pharmaceuticals · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study is to compare the efficacy and safety of increasing doses of SLV306 with amlodipine.

02

Conditions studied

  • Hypertension

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Keywords

  • blood pressure
03

In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.

Browse Hypertension studies →

Lead sponsor

Solvay Pharmaceuticals is the lead sponsor of 84 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • sitting office diastolic blood pressure between 90 and 109 mmHg
  • office systolic blood pressure between 140 and 179 mmHg
  • mean day-time diastolic 24-h ABPM blood pressure >= 85 mmHg inclusive at baseline

Exclusion criteria

Exclusion Criteria:

  • known secondary hypertension
  • decompensated congestive heart failure
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double

Interventions

  • DrugDaglutril
06

Study locations

130 sites
  • Site 705
    Bracken Ridge, Australia
  • Site 706
    Caboolture, Australia
  • Site 700
    Inala, Australia
  • Site 701
    Kippa Ring, Australia
  • Site 702
    Melbourne, Australia
  • Site 703
    Nedlands, Australia
  • Site 952
    Haskovo, Bulgaria
  • Site 955
    Pleven, Bulgaria
  • Site 951
    Plovdiv, Bulgaria
  • Site 956
    Plovdiv, Bulgaria
  • Site 950
    Sofia, Bulgaria
  • Site 953
    Sofia, Bulgaria
  • Site 954
    Sofia, Bulgaria
  • Site 957
    Sofia, Bulgaria
  • Site 402
    Aalborg, Denmark
  • Site 401
    Ballerup, Denmark
  • Site 403
    Vejle, Denmark
  • Site 850
    Tallinn, Estonia
  • Site 119
    Aschaffenburg, Germany
  • Site 101
    Bad Nauheim, Germany
  • Site 104
    Bad Woerishofen, Germany
  • Site 106
    Beckum, Germany
  • Site 110
    Deidesheim, Germany
  • Site 107
    Karlsruhe, Germany
  • Site 118
    Kassel, Germany
  • Site 109
    Krombach, Germany
  • Site 113
    Ladenburg, Germany
  • Site 102
    Leipzig, Germany
  • Site 112
    Lollar, Germany
  • Site 114
    Magdeburg, Germany
  • Site 111
    Marburg, Germany
  • Site 105
    Muenster, Germany
  • Site 115
    Niederstetten, Germany
  • Site 120
    Rodgau Dudenhofen, Germany
  • Site 116
    Vellmar, Germany
  • Site 103
    Wiesbaden, Germany
  • Site 117
    Wolmirstedt, Germany
  • Site 800
    Budapest, Hungary
  • Site 805
    Budapest, Hungary
  • Site 803
    Gyongyos, Hungary
  • Site 801
    Kecskemet, Hungary
  • Site 804
    Pecs, Hungary
  • Site 802
    Szekesfehervar, Hungary
  • Site 300
    Ashkelon, Israel
  • Site 306
    Ashkelon, Israel
  • Site 304
    Beer Sheva, Israel
  • Site 311
    Haifa, Israel
  • Site 305
    Jerusalem, Israel
  • Site 310
    Kfar Saba, Israel
  • Site 303
    Kiryat Ata, Israel
  • Site 308
    Petach-Tikva, Israel
  • Site 302
    Tel-Aviv, Israel
  • Site 301
    Tel-Hashomer, Israel
  • Site 309
    Tiberias, Israel
  • Site 932
    Daugavpils, Latvia
  • Site 930
    Kuldiga, Latvia
  • Site 931
    Riga, Latvia
  • Site 933
    Riga, Latvia
  • Site 934
    Riga, Latvia
  • Site 935
    Riga, Latvia
  • Site 920
    Kaunas, Lithuania
  • Site 923
    Klaipeda, Lithuania
  • Site 921
    Vilnius, Lithuania
  • Site 600
    Bratislava, Slovakia
  • Site 601
    Bratislava, Slovakia
  • Site 607
    Kosice, Slovakia
  • Site 608
    Kosice, Slovakia
  • Site 602
    Levice, Slovakia
  • Site 605
    Lucenec, Slovakia
  • Site 603
    Nove Zamky, Slovakia
  • Site 606
    Vrable, Slovakia
  • Site 262
    Addlestone, United Kingdom
  • Site 229
    Airdrie, United Kingdom
  • Site 234
    Alexandria, United Kingdom
  • Site 245
    Bangor, United Kingdom
  • Site 241
    Barrhead, United Kingdom
  • Site 224
    Bath, United Kingdom
  • Site 240
    Bath, United Kingdom
  • Site 230
    Bellshill, United Kingdom
  • Site 261
    Bexhill on sea, United Kingdom
  • Site 243
    Bexhill- on-Sea, United Kingdom
  • Site 255
    Blackpool, United Kingdom
  • Site 222
    Blantyre, United Kingdom
  • Site 232
    Calderbank, United Kingdom
  • Site 236
    Chesterfield, United Kingdom
  • Site 219
    Chippenham, United Kingdom
  • Site 256
    Chippenham, United Kingdom
  • Site 237
    Co Tyrone, United Kingdom
  • Site 216
    Coatbridge, United Kingdom
  • Site 238
    Cornwall, United Kingdom
  • Site 207
    Coventry, United Kingdom
  • Site 247
    Cumbernauld, United Kingdom
  • Site 208
    Dumbarton, United Kingdom
  • Site 235
    East Horsley, United Kingdom
  • Site 220
    Ely, United Kingdom
  • Site 257
    Frome, United Kingdom
  • Site 210
    Glasgow, United Kingdom
  • Site 221
    Glasgow, United Kingdom
  • Site 227
    Glasgow, United Kingdom
  • Site 233
    Glasgow, United Kingdom

Showing the first 100 of 130 sites across 11 countries.

07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 30, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00160212
Lead sponsor
Solvay Pharmaceuticals
First posted
Sep 12, 2005
Start date
Dec 2004
Last update
Jan 30, 2009

Study contacts

Global Clinical Director Solvay
study director · Solvay Pharmaceuticals
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2009. You cannot join it, but the record below documents what was studied.

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