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CompletedNCT00160160Updated Jan 30, 2009

Comparison of Eprosartan/HCT Versus Enalapril/HCT in Hypertensives With Type II Diabetes

An interventional study of eprosartan/HCTZ in Hypertension and Type 2 Diabetes, sponsored by Solvay Pharmaceuticals. Completed at 63 sites in 9 countries. Open to participants aged 40 Years to 80 Years. Per ClinicalTrials.gov, last updated 2009-01-30.

Sponsored by Solvay Pharmaceuticals · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
440
Allocation
Randomized
Ages
40 Years to 80 Years
Sex
All
01

Study summary

This study is to demonstrate the superiority of combination of eprosartan/HCTZ versus ramipril/HCTZ.

02

Conditions studied

  • Hypertension
  • Type 2 Diabetes

Keywords

  • comparator trial
  • hypertension
  • diabetes
  • blood pressure
03

In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.

This study's enrollment of 440 is above the median of 90 across 4,995 interventional studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

Solvay Pharmaceuticals is the lead sponsor of 84 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • essential hypertension,
  • diabetes type 2

Exclusion criteria

Exclusion Criteria:

  • severe cardiovascular disease,
  • grade 3 hypertension,
  • secondary hypertension,
  • abnormal liver enzymes
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
440 participants

Interventions

  • Drugeprosartan/HCTZ
06

What researchers measure

Primary outcomes

  1. Blood pressure reduction

Secondary outcomes

  1. Comparison of responder rates

07

Study locations

63 sites
  • Site 26
    Calgary, Canada
  • Site 27
    Montreal, Canada
  • Site 30
    Quebec, Canada
  • Site 31
    Thornhill, Canada
  • Site 28
    Vancouver, Canada
  • Site 29
    Winnipeg, Canada
  • Site 39
    Holbaek, Denmark
  • Site 38
    Roskilde, Denmark
  • Site 40
    Viborg, Denmark
  • Site 4
    Anzin, France
  • Site 3
    Blois, France
  • Site 10
    Chemellier, France
  • Site 11
    Cholet, France
  • Site 15
    Cholet, France
  • Site 16
    Cholet, France
  • Site 14
    La Jubaudiere, France
  • Site 13
    Le Mesnil-en-Vallee, France
  • Site 7
    Murs-Erigne, France
  • Site 9
    Saumur, France
  • Site 8
    Segre, France
  • Site 12
    St Pierre Montlim, France
  • Site 6
    Thouars, France
  • Site 2
    Tours, France
  • Site 5
    Vieux Conde, France
  • Site 20
    Bad Muenster, Germany
  • Site 22
    Floersheim, Germany
  • Site 19
    Kirweiler, Germany
  • Site 21
    Lambrecht, Germany
  • Site 25
    Lindau, Germany
  • Site 18
    Lueneburg, Germany
  • Site 24
    Lutherstadt, Germany
  • Site 17
    Riesa, Germany
  • Site 23
    Waldbrunn, Germany
  • Site 62
    Bologna, Italy
  • Site 60
    Napoli, Italy
  • Site 58
    Padova, Italy
  • Site 59
    Palermo, Italy
  • Site 63
    Pavia, Italy
  • Site 61
    Pisa, Italy
  • Site 64
    Torino, Italy
  • Site 43
    Alesund, Norway
  • Site 42
    Bergen, Norway
  • Site 44
    Horten, Norway
  • Site 41
    Skedsmokorset, Norway
  • Site 55
    Badajoz, Spain
  • Site 51
    Badalona, Spain
  • Site 56
    Barcelona, Spain
  • Site 57
    Barcelona, Spain
  • Site 54
    Ciudad Real, Spain
  • Site 53
    Granada, Spain
  • Site 52
    Madrid, Spain
  • Site 48
    Angelholm, Sweden
  • Site 47
    Goteburg, Sweden
  • Site 46
    Helsingborg, Sweden
  • Site 45
    Kristianstat, Sweden
  • Site 50
    Malmo, Sweden
  • Site 49
    Stockholm, Sweden
  • Site 33
    Aberdeen, United Kingdom
  • Site 36
    Bath, United Kingdom
  • Site 37
    Liverpool, United Kingdom
  • Site 34
    Manchester, United Kingdom
  • Site 32
    Oldham, United Kingdom
  • Site 35
    Rugby, United Kingdom
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 30, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00160160
Lead sponsor
Solvay Pharmaceuticals
First posted
Sep 12, 2005
Start date
Oct 2004
Last update
Jan 30, 2009

Study contacts

Global Clinical Director Solvay
study director · Solvay Pharmaceuticals
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2009. You cannot join it, but the record below documents what was studied.

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