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CompletedNCT00137748Updated Jun 10, 2010

Cytomegalovirus Hyperimmune Globulin (CMV-Ig) Replacement in Hypogammaglobulinemic Lung Transplant Recipients

A Phase 2/3 interventional study of CMV-Ig in Hypogammaglobulinemia, sponsored by The Cleveland Clinic. Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2010-06-10.

Sponsored by The Cleveland Clinic · Phase 2/3, Interventional, and Prevention

Phase
Phase 2/3
Study type
Interventional
Enrollment
50
Allocation
Randomized
Sex
All
01

Study summary

This is a randomized controlled trial of CMV-Ig in lung transplant recipients at the Cleveland Clinic Foundation who are hypogammaglobulinemic.

Read the detailed description

This is a randomized controlled trial of CMV-Ig in lung transplant recipients at the Cleveland Clinic Foundation who are hypogammaglobulinemic.

02

Conditions studied

  • Hypogammaglobulinemia

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Keywords

  • Lung transplantation
03

In context

Agammaglobulinemia

44 studies on the registry are indexed under Agammaglobulinemia; 10 are open to participants now.

This study's planned enrollment of 50 is above the median of 44 across 34 interventional studies indexed under Agammaglobulinemia.

Browse Agammaglobulinemia studies →

Lead sponsor

The Cleveland Clinic is the lead sponsor of 818 studies on the registry; 118 are open to participants now.

Of its 89 completed or terminated interventional studies of FDA-regulated products, 72 (81%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Eligibility criteria

Inclusion Criteria:

  • Lung transplant
  • Hypogammaglobulinemia
05

Study design

Phase
Phase 2 / Phase 3
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
50 participants (estimated)

Interventions

  • DrugCMV-Ig

    Drug: CMV-Ig

06

What researchers measure

Primary outcomes

  1. CMV infection

07

Study locations

1 site
  • Cleveland Clinic Foundation
    Cleveland, Ohio 44195, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 10, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00137748
Lead sponsor
The Cleveland Clinic
First posted
Aug 30, 2005
Start date
Jan 2001
Primary completion
Jan 2006
Completion
Jan 2006
Last update
Jun 10, 2010

Study contacts

Jeff T Chapman, MD
principal investigator · The Cleveland Clinic
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2010. You cannot join it, but the record below documents what was studied.

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