ClinicalTrials.gg
TerminatedNCT00137293Updated Dec 10, 2007

Study Evaluating GAP-486 in Heart Rhythm

A Phase 2 interventional study of GAP-486 (ZP-123) and 0.9% Sodium Chloride, USP in Arrhythmia, sponsored by Wyeth is now a wholly owned subsidiary of Pfizer. Terminated at 7 sites in 2 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2007-12-10.

Sponsored by Wyeth is now a wholly owned subsidiary of Pfizer (part of Pfizer) · Phase 2 and Interventional

Phase
Phase 2
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to learn the effects of a test drug on heart rhythm, and to provide additional data to see if the test drug is well tolerated and safe.

02

Conditions studied

  • Arrhythmia

Keywords

  • Arrhythmia, syncope, antiarrhythmic
03

In context

Arrhythmias, Cardiac

915 studies on the registry are indexed under Arrhythmias, Cardiac; 234 are open to participants now.

This study's enrollment of 30 is below the median of 97 across 443 interventional studies indexed under Arrhythmias, Cardiac.

Browse Arrhythmias, Cardiac studies →

Lead sponsor

Wyeth is now a wholly owned subsidiary of Pfizer is the lead sponsor of 484 studies on the registry; none are open to participants now.

First submitted before Wyeth became part of Pfizer.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients undergoing an electrophysiology study for evaluation of heart rhythm.

Exclusion criteria

Exclusion Criteria:

  • Patients with uncontrolled blood pressure
  • Patients with certain cardiac risk factors
  • Patients with significant kidney or liver problems
05

Study design

Phase
Phase 2
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
30 participants

Interventions

06

What researchers measure

Primary outcomes

  1. This study takes place within 24 hours. The measure to determine the effect of the intervention will be the difference in values from the baseline electrophysiology study, and the values obtained after intervention within the test drug.

Secondary outcomes

  1. This study takes place within 24 hours, and looks at the changes in values of electrophysiology studies, before and after administration of test article.

07

Study locations

7 sites
  • San Francisco, California 94143, United States
  • Washington D.C., District of Columbia 20010, United States
  • Hershey, Pennsylvania 17033, United States
  • Ottawa, Ontario K1Y 4W7, Canada
  • Toronto, Ontario M5B 1W8, Canada
  • Montreal, Quebec H1T 1CB, Canada
  • Montreal, Quebec H2L 4M1, Canada
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 10, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00137293
First posted
Aug 29, 2005
Start date
Nov 2005
Completion
Oct 2006
Last update
Dec 10, 2007

Study contacts

Medical Monitor
study director · Wyeth is now a wholly owned subsidiary of Pfizer
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Dec 2007. You cannot join it, but the record below documents what was studied.

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Discussion

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