An interventional study of plastic wrap over eye & lubrication applied q6 hrs in Eye Injuries and Critically Ill, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago. Completed at 2 sites in United States. Open to participants aged 2 Weeks to 17 Years. Per ClinicalTrials.gov, last updated 2007-07-10.
Sponsored by Ann & Robert H Lurie Children's Hospital of Chicago · Not applicable, Interventional, and Prevention
The purpose of this study is to identify the incidence of scratches on the surface of the eye in children who cannot blink due to medication use and to identify how best to reduce the risk of a scratch on the surface of the eye when patients are using specific medicines.
Critically ill children may require neuromuscular blockade as a treatment modality. These children require careful eye care to prevent corneal abrasions. However, current evidence does not exist to guide best practices on eye care. This research study will evaluate 2 types of eye care therapy. The eyes will be randomly assigned to the control or experimental eye care therapy group. The control eye will receive lubricating ointment every 6 hours. The experimental eye will receive lubricating ointment every 6 hours and have a plastic covering to create a moisture chamber. Using daily fluorescein staining to detect corneal abrasions, each child will be studied for up to 9 days. Children who develop corneal abrasions will be discharged from the study and the primary care team will be notified. The two groups will then be compared to determine the therapy associated with the lowest incidence of corneal abrasions.
32 studies on the registry are indexed under Corneal Injuries; 9 are open to participants now.
This study's enrollment of 207 is above the median of 37 across 24 interventional studies indexed under Corneal Injuries.
Browse Corneal Injuries studies →Ann & Robert H Lurie Children's Hospital of Chicago is the lead sponsor of 176 studies on the registry; 30 are open to participants now.
Of its 10 completed or terminated interventional studies of FDA-regulated products, 5 (50%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Development of corneal abrasions
Time frame: 9 days
Incidence of corneal abrasions
Time frame: 36 hours
This study is completed, as verified in Jul 2007. You cannot join it, but the record below documents what was studied.
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Ann & Robert H Lurie Children's Hospital of Chicago