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CompletedNCT00110487Updated May 1, 2015

Study Evaluating ERB-041 in Endometriosis in Reproductive-Age Women

A Phase 2 interventional study of ERB-041 in Endometriosis, sponsored by Wyeth is now a wholly owned subsidiary of Pfizer. Completed at 46 sites in United States. Open to female participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2015-05-01.

Sponsored by Wyeth is now a wholly owned subsidiary of Pfizer (part of Pfizer) · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Enrollment
200
Allocation
Randomized
Ages
18 Years to 45 Years
Sex
Female
01

Study summary

The purpose of this investigational study is to determine if a study medication is safe and effective in reducing the symptoms associated with endometriosis; if the study medication reduces the need for pain medication for endometriosis symptoms; and if the study medication improves a participant's ability to carry out daily activities. Qualified participants will receive no cost treatment, which may include study-related examinations, diagnostic procedures including a Pap smear, laboratory testing, and a mammogram (aged 40-45). Qualified participants will also receive study medication at no cost. As a participant, the study volunteer may also experience the satisfaction of knowing she is helping the advancement of women's health care.

02

Conditions studied

  • Endometriosis

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Keywords

  • Endometriosis
03

In context

Endometriosis

925 studies on the registry are indexed under Endometriosis; 264 are open to participants now.

This study's enrollment of 200 is above the median of 65 across 539 interventional studies indexed under Endometriosis.

Browse Endometriosis studies →

Lead sponsor

Wyeth is now a wholly owned subsidiary of Pfizer is the lead sponsor of 484 studies on the registry; none are open to participants now.

First submitted before Wyeth became part of Pfizer.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 45 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Surgical diagnosis of endometriosis within 5 years
  • Not pregnant and not lactating
  • Willing to use non-hormonal contraception, history of regular menstrual cycles

Exclusion criteria

Exclusion Criteria:

  • Hysterectomy, surgical treatment for endometriosis within 3 months
  • Certain medications for the treatment of endometriosis
  • Previous history of a malignancy
  • Abnormalities on physical or gyn exams and abnormal lab tests
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Single group
Masking
Double
Enrollment
200 participants

Interventions

06

What researchers measure

Primary outcomes

  1. To assess the effects and to compare the safety profile of an investigational

  2. medication on the relief of endometriosis-related symptoms.

Secondary outcomes

  1. Clinical and subject assessment of symptoms related to endometriosis and the

  2. use of analgesia to relieve symptoms.

07

Study locations

46 sites
  • Phoenix, Arizona 85015, United States
  • Tucson, Arizona 85710, United States
  • Carmichael, California 95608, United States
  • La Jolla, California 92093, United States
  • Redding, California 96001, United States
  • San Diego, California 92123, United States
  • Lakewood, Colorado 80228, United States
  • Aventura, Florida 33180, United States
  • Boynton Beach, Florida 33437, United States
  • Celebration, Florida 34747, United States
  • Clearwater, Florida 33758, United States
  • Miami, Florida 33136, United States
  • Miami, Florida 33143, United States
  • New Port Richey, Florida 34652, United States
  • Ocala, Florida 34471, United States
  • Palm Harbor, Florida 34684, United States
  • Alpharetta, Georgia 30005, United States
  • Atlanta, Georgia 30342, United States
  • Arlington Heights, Illinois 60005, United States
  • Champaign, Illinois 61820, United States
  • Chicago, Illinois 60611, United States
  • Chicago, Illinois 60637, United States
  • Oak Brook, Illinois 60523, United States
  • South Bend, Indiana 46601, United States
  • Shreveport, Louisiana 71103, United States
  • Lanham, Maryland 20706, United States
  • Laurel, Maryland 20707, United States
  • Detroit, Michigan 48201, United States
  • Chaska, Minnesota 55318, United States
  • Chesterfield, Missouri 63017, United States
  • Las Vegas, Nevada 89104, United States
  • Berlin, New Jersey 08009, United States
  • Charlotte, North Carolina 28209, United States
  • Fargo, North Dakota 58104, United States
  • Cincinnati, Ohio 45267, United States
  • Cleveland, Ohio 44195, United States
  • Eugene, Oregon 97401, United States
  • Greenville, South Carolina 29605, United States
  • Greer, South Carolina 29651, United States
  • Dallas, Texas 75390-9032, United States
  • Fort Worth, Texas 76104, United States
  • Webster, Texas 77598, United States
  • Sandy City, Utah 84070, United States
  • Norfolk, Virginia 23507-1627, United States
  • Richmond, Virginia 23298, United States
  • Madison, Wisconsin 53792-6188, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 1, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00110487
First posted
May 10, 2005
Start date
Jan 2005
Completion
Dec 2006
Last update
May 1, 2015

Study contacts

Medical Monitor
study director · Wyeth is now a wholly owned subsidiary of Pfizer
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2007. You cannot join it, but the record below documents what was studied.

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Discussion

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