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CompletedNCT00109980Updated Nov 1, 2013

Medicinal Plant Use for Treating Inflammation Among Dominicans in New York City and the Dominican Republic

An observational study in Inflammation, sponsored by New York Botanical Garden. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-11-01.

Sponsored by New York Botanical Garden · Observational

Study type
Observational
Model
Ecologic or community
Time perspective
Cross-sectional
Enrollment
320
Ages
18 Years and older
Sex
All
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Study summary

The purpose of this study is to investigate and compare the use of herbal medicine among Dominicans in New York City and the Dominican Republic.

Read the detailed description

According to the 2000 U.S. Census Report, Dominicans constitute the largest Hispanic immigrant group in New York City. Studies have shown that immigrants' use of traditional and herbal medicine is close to that of native-born Americans. However, minority immigrants often have limited access to traditional health care; as a result, they may be more likely to consult with traditional healers and use medicinal plants than nonimmigrants. This study is designed to increase knowledge about immigrants' health and to contribute to more culturally-sensitive health care. The purpose of this study is to determine medical plant knowledge and use among Dominican traditional healers and patients in New York City and in the Dominican Republic.

This study will comprise two parts. In Part I, Dominican medicinal plant users and Dominican traditional healers in New York City will be questioned about the medicinal plant species they know and how they are used for prevalent illnesses. The same number of participants will be interviewed in the Dominican Republic, allowing for detailed comparisons between the two study sites.

In Part II, the most frequently-cited medicinal plant species will be subjected to a thorough literature review on their pharmacologic activity and the chemical composition of their active constituents. Two in vitro assays will be used to measure the anti-inflammatory activity of certain plant extracts, and their anti-inflammatory compounds will be isolated and characterized for the purpose of standardization of active extracts. On the basis of these results, recommendations will be formulated for future studies and community use of selected medicinal plant species.

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Conditions studied

  • Inflammation

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Keywords

  • Complementary Therapies
  • Plants, Medicinal
  • Dominican Republic
  • Hispanic Americans
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In context

Inflammation

3,438 studies on the registry are indexed under Inflammation; 629 are open to participants now.

This study's enrollment of 320 is above the median of 95 across 895 observational studies indexed under Inflammation.

Browse Inflammation studies →

Lead sponsor

This is the only study on the registry with New York Botanical Garden as lead sponsor.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Dominican community sample in New York City

Eligibility criteria

Inclusion Criteria:

  • Dominican ethnicity
  • Have knowledge of Dominican medicinal plants
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Study design

Observational model
Ecologic or community
Time perspective
Cross-sectional
Enrollment
320 participants (actual)
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What researchers measure

Primary outcomes

  1. Identification of culturally important medicinal plants

    Time frame: June 2010

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Study locations

1 site
  • Associates in Internal Medicine Clinic, New York-Presbyterian Hospital, Columbia University
    New York City, New York 10032, United States
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References and documents

Publications

  • Balick MJ, Kronenberg F, Ososki AL, Reiff M, Fugh-Berman A, O'Connor B, Roble M, Lohr P, Atha D. Medicinal plants used by Latino healers for women's health conditions in New York City. Economic Botany 54: 344-357, 2000.
  • Balick MJ, Lee R. Looking within: urban ethnomedicine and ethnobotany. Altern Ther Health Med. 2001 Jul-Aug;7(4):114-5. No abstract available. PubMed 11452554 ↗
  • Fugh-Berman A, Balick MJ, Kronenberg F, Ososki AL, O'Connor B, Reiff M, Roble M, Lohr P, Brosi BJ, Lee R. Treatment of fibroids: the use of beets (Beta vulgaris) and molasses (Saccharum officinarum) as an herbal therapy by Dominican healers in New York City. J Ethnopharmacol. 2004 Jun;92(2-3):337-9. doi: 10.1016/j.jep.2004.03.009. No abstract available. PubMed 15138021 ↗
  • Ososki AL, Lohr P, Reiff M, Balick MJ, Kronenberg F, Fugh-Berman A, O'Connor B. Ethnobotanical literature survey of medicinal plants in the Dominican Republic used for women's health conditions. J Ethnopharmacol. 2002 Mar;79(3):285-98. doi: 10.1016/s0378-8741(01)00376-2. PubMed 11849831 ↗
  • Reiff M, O'Connor B, Kronenberg F, Balick M, Lohr P, Roble M, Fugh-Berman A, Johnson KD. Ethnomedicine in the urban environment: Dominican healers in New york City. Human Organization 62(1): 12-26, 2003.
  • Vandebroek I, Balick MJ, Yukes J, Duran L, Kronenberg F, Wade C, Ososki AL, Cushman L, Lantigua R, Mejia M & Robineau L (2007) Use of medicinal plants by Dominican immigrants in New York City for the treatment of common health conditions. A comparative analysis with literature data from the Dominican Republic. In: A. Pieroni & I. Vandebroek, eds., Traveling Cultures and Plants: The Ethnobiology and Ethnopharmacy of Human Migrations. Bergahn Books, New York, pp. 39-63.
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 1, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00109980
Lead sponsor
New York Botanical Garden
Responsible party
Michael Balick (Director, National Center for Complementary and Integrative Health (NCCIH)) — Principal investigator
First posted
May 4, 2005
Start date
Mar 2005
Primary completion
Jul 2011
Last update
Nov 1, 2013

Study contacts

Michael J. Balick, PhD
principal investigator · Institute of Economic Botany, the New York Botanical Garden

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2013. You cannot join it, but the record below documents what was studied.

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