An interventional study of Maternal interpersonal psychotherapy (IP) and Infant-parent psychotherapy in Depression, sponsored by University of Rochester. Completed at 1 site in United States. Open to female participants aged 18 Years to 44 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-04-30.
Sponsored by University of Rochester · Not applicable, Interventional, and Treatment
This study will compare three interventions for depressed, low income mothers and determine which is most effective in treating maternal depression and in fostering development in infants.
Poorly educated, low income mothers are at high risk for becoming depressed. The effects of living in poverty and being reared by a depressed parent can be detrimental to an infant's development. Effective interventions to reduce maternal depression and strengthen the mother-infant relationships are needed.
Participants will be randomly assigned to one of three groups. Group 1 mothers will receive 16 weekly sessions of interpersonal psychotherapy (IP) designed to directly treat maternal depression. Group 1 participants will have monthly follow-up visits for 1 year. Participants in Group 2 will receive 16 weekly sessions of IP followed by 1 year of in-home, infant-parent psychotherapy, an intervention addressing relationship difficulties between depressed mothers and their infants. Group 3 mothers will be invited to attend informational meetings as well as be referred to local services available to people with depression.
All mother-child pairs will be evaluated when the child is 12, 16, 24, and 36 months of age. Evaluations will involve questionnaires, diagnostic interviews, developmental assessments, and video- and audio-taped measures.
8,055 studies on the registry are indexed under Depression; 1,643 are open to participants now.
This study's enrollment of 218 is above the median of 84 across 6,718 interventional studies indexed under Depression.
Browse Depression studies →University of Rochester is the lead sponsor of 715 studies on the registry; 116 are open to participants now.
Of its 56 completed or terminated interventional studies of FDA-regulated products, 44 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria for Mothers:
Participants will receive interpersonal psychotherapy for depression.
Behavioral: Maternal interpersonal psychotherapy (IP)
Participants will receive interpersonal psychotherapy for depression plus 1 year of in-home, child-parent psychotherapy.
Behavioral: Maternal interpersonal psychotherapy (IP) · Behavioral: Infant-parent psychotherapy
Participants will be invited to attend informational meetings as well as be referred to local services available to people with depression.
Behavioral: Informational meetings plus treatment as usual
Participants will receive 16 weekly sessions of maternal IP designed to directly treat maternal depression.
Participants will receive 1 year of in-home, infant-parent psychotherapy, an intervention addressing relationship difficulties between depressed mothers and their infants.
Participants will be invited to attend informational meetings as well as be referred to local services available to people with depression.
Maternal depression
Time frame: Measured when the child is 12, 16, 24, 36, and 48 months of age
Child development
Time frame: Measured when the child is 12, 16, 24, 36, and 48 months of age
Infant-parent attachment
Time frame: Measured when the child is 12, 16, 24, 36, and 48 months of age
This study is completed, as verified in Apr 2013. You cannot join it, but the record below documents what was studied.
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University of Rochester