A Phase 3 interventional study of Tight control of blood glucose levels and Conventional control of glucose levels in Critical Illness, Hyperglycemia and Insulin Resistance, sponsored by Hospital Pablo Tobón Uribe. Completed at 1 site in Colombia. Open to participants aged 15 Years and older. Per ClinicalTrials.gov, last updated 2006-10-26.
Sponsored by Hospital Pablo Tobón Uribe · Phase 3, Interventional, and Treatment
The purpose of this study is to evaluate the impact of tight control of serum glucose levels with an intensive insulin treatment in patients hospitalized in an intensive care unit with medical and surgical patients.
Reduction of morbidity-mortality in critical care patients with tight glycemic control had been proven in surgical patients only.
Study Hypothesis: In critical care patients, medical or surgical, a glucose serum level between 80 - 110 mg/dL means a lower mortality than patients with glucose levels of more than 110 mg/dL.
800 studies on the registry are indexed under Hyperglycemia; 115 are open to participants now.
This study's enrollment of 504 is above the median of 50 across 620 interventional studies indexed under Hyperglycemia.
Browse Hyperglycemia studies →Hospital Pablo Tobón Uribe is the lead sponsor of 7 studies on the registry; none are open to participants now.
Compared within Hyperglycemia, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Critical Illness. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Mortality in the next 28 days
Mortality during intensive care
Mortality overall in-hospital
Mortality among patients who remained in the intensive care unit for more than five days
Infections incidence in the critical care unit: nosocomial pneumonia, urinary tract infection and catheter related infection
Length of stay in the unit
Days of ventilatory support
Acute renal failure requiring dialysis or hemofiltration
The median number of red-cell transfusions
SOFA score
Critical-illness polyneuropathy
The record gives a start of Jul 2003 and a completion of Sep 2006. It does not say whether these dates are actual or estimated.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Oct 2006. You cannot join it, but the record below documents what was studied.
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Hospital Pablo Tobón Uribe