An observational study in SARS Virus, sponsored by National Institute of Allergy and Infectious Diseases (NIAID). Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2017-07-02.
Sponsored by National Institute of Allergy and Infectious Diseases (NIAID) · Observational
Severe Acute Respiratory Syndrome (SARS) is a newly recognized illness that can be fatal.
The purpose of this study is to better understand SARS by collecting samples of blood and other body fluids of people who have been exposed to SARS or who are suspected to have the illness.
Up to 300 volunteers aged 18 years or older will be enrolled in this study. Participants will donate blood samples and, if appropriate, samples of fluid from the lungs, nose, or throat. Researchers will test these samples for proteins that control or mediate inflammatory or immune responses. The patterns of these proteins will reveal how SARS affects the body and the efforts the body makes to fight off the infection.
Severe acute respiratory syndrome (SARS) is a newly recognized illness associated with substantial mobidity and mortality. Patients develop fever followed by rapidly progressive and even fatal respiratory disease. SARS is associated with infection with a novel coronavirus. The evaluation of the inflammatory responses evoked by SARS may yield information regarding its pathogenesis and help with patient management. This protocol, then, merely aims to study disease pathogenesis and natural history, by studying samples and data that are collected by outside physicians or physicians at the Clinical Center and sent for evaluation of the inflammatory response.
382 studies on the registry are indexed under Severe Acute Respiratory Syndrome; 14 are open to participants now.
This study's enrollment of 400 is above the median of 300 across 140 observational studies indexed under Severe Acute Respiratory Syndrome.
Browse Severe Acute Respiratory Syndrome studies →National Institute of Allergy and Infectious Diseases (NIAID) is the lead sponsor of 2,401 studies on the registry; 179 are open to participants now.
Of its 396 completed or terminated interventional studies of FDA-regulated products, 294 (74%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients fulfilling the CDC case definition or WHO definition for suspected or probable SARS.
Newly identified patients found to have recovered from SARS can also be enrolled.
EXCLUSION CRITERIA - CASES:
Patients diagnosed with alternative illnesses as the cause of the symptoms.
INCLUSION CRITERIA - HEALTHY VOLUNTEERS:
For the purpose of this study, a healthy volunteer is defined as a healthy male or female, age 18 and above.
Volunteers will be excluded if they have a pre-existing or concurrent serious chronic medical or psychiatric illness.
Chronic medication use will be evaluated on a case-by-case basis.
They will also be excluded if they have received an investigational drug in the past 3 months.
This study is completed, as verified in May 2007. You cannot join it, but the record below documents what was studied.
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Severe Acute Respiratory Syndrome→
National Institute of Allergy and Infectious Diseases (NIAID)