CClinicalTrials.gg
TerminatedNCT00051688Updated Jul 11, 2006

Tezacitabine and Oxaliplatin for the Treatment of Patients With Metastatic Colorectal Cancer

A Phase 2 interventional study of tezacitabine and oxaliplatin in Colorectal Neoplasms, sponsored by Chiron Corporation. Terminated at 8 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2006-07-11.

Sponsored by Chiron Corporation · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Ages
18 Years and older
Sex
All
01

Study summary

The primary purpose of this study is to determine the best dose of tezacitabine when combined with oxaliplatin in patients with metastatic colorectal cancer. This study will also evaluate tumor response to the combination of anti-cancer drugs.

02

Conditions studied

  • Colorectal Neoplasms
03

In context

Colorectal Neoplasms

5,599 studies on the registry are indexed under Colorectal Neoplasms; 1,459 are open to participants now.

Browse Colorectal Neoplasms studies →

Lead sponsor

Chiron Corporation is the lead sponsor of 11 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Eligibility criteria

  • Patients with metastatic colorectal adenocarcinoma who have failed one prior course of chemotherapy.
  • Patients must have at least one measurable tumor.
  • Patients may not have received prior treatment with oxaliplatin.
05

Study design

Phase
Phase 2
Primary purpose
Treatment

Interventions

  • Drugtezacitabine
  • Drugoxaliplatin
06

Study locations

8 sites
  • ACRC/Arizona Clinical Research Center
    Tucson, Arizona 85712, United States
  • USC/Norris Comprehensive Cancer Center
    Los Angeles, California 90033, United States
  • Comprehensive Cancer Centers of the Desert
    Palm Springs, California 92262, United States
  • Cancer Institute Medical Group
    Santa Monica, California 90404, United States
  • Georgetown University Medical Center, Lombardi Cancer Center
    Washington, District of Columbia 20007, United States
  • H. Lee Moffitt Cancer Center & Research Institute
    Tampa, Florida 33612-9497, United States
  • Northwestern University Feinberg School of Medicine
    Chicago, Illinois 60611, United States
  • Kansas City Oncology and Hematology Group
    Kansas City, Missouri 64111, United States
07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 11, 2006, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00051688
Lead sponsor
Chiron Corporation
First posted
Jan 16, 2003
Start date
Jun 2003
Completion
Aug 2004
Last update
Jul 11, 2006
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Jul 2006. You cannot join it, but the record below documents what was studied.

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