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TerminatedNCT00005427Updated Mar 12, 2024

Cohort Study of Respiratory Illness in Early Childhood

An observational study in Lung Diseases, sponsored by University of New Mexico. Terminated. Open to male participants aged 0 Years to 100 Years. Per ClinicalTrials.gov, last updated 2024-03-12.

Sponsored by University of New Mexico · Observational

Why this study was terminated
Not a clinical trial.
Study type
Observational
Ages
0 Years to 100 Years
Sex
Male
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Study summary

To analyze previously collected data on respiratory illness in early childhood.

Read the detailed description

BACKGROUND:

The study built on a previous study funded by the Health Effects Institute, a non-profit foundation jointly supported by the U.S. Environmental Protection Agency and vehicle manufacturers. The previous study was a prospective cohort study of nitrogen dioxide (NO2) exposure and respiratory symptoms and illnesses during the first 18 months of life. Between January, 1988 and June, 1990, 1,315 infants were enrolled and then followed with collection of daily respiratory symptom data and serial monitoring of NO2 concentrations in their homes. The full protocol was completed by 823 subjects and a total follow-up experience of over one-half million days was accumulated. Follow-up ended in December, 1991 and analyses related to the study's principal focus, the health effects of NO2, was completed during the fall of 1992.

DESIGN NARRATIVE:

The analyses were directed at the following: 1) Time spent in day-care and the incidence and severity of respiratory illnesses; 2) Breast-feeding and the incidence and severity of respiratory illnesses during the first six months of life; 3) Determinants of wheezing and wheezing illnesses; 4) Determinants of a physician-diagnosis of asthma; 5) Exposure to woodsmoke and incidence and severity of respiratory illnesses; 6) Household demographics, including ethnicity, and incidence and severity of respiratory illnesses; 7) Determinants of the duration of respiratory illnesses; 8) The validity of retrospective parental reports of respiratory illness; 9) Parental perceptions of the risks of indoor and outdoor air pollution; 10) Clinical findings on assessment of ill children in the community.

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Conditions studied

  • Lung Diseases

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03

In context

Lung Diseases

3,303 studies on the registry are indexed under Lung Diseases; 355 are open to participants now.

Browse Lung Diseases studies →

Lead sponsor

University of New Mexico is the lead sponsor of 306 studies on the registry; 28 are open to participants now.

Of its 25 completed or terminated interventional studies of FDA-regulated products, 23 (92%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
0 Years to 100 Years
Sexes eligible
Male
Accepts healthy volunteers
No

Eligibility criteria

No eligibility criteria

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Study design

06

Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Bosken CH, Hunt WC, Lambert WE, Samet JM. A parental history of asthma is a risk factor for wheezing and nonwheezing respiratory illnesses in infants younger than 18 months of age. Am J Respir Crit Care Med. 2000 Jun;161(6):1810-5. doi: 10.1164/ajrccm.161.6.9903030. PubMed 10852749 ↗
  • Cushing AH, Samet JM, Lambert WE, Skipper BJ, Hunt WC, Young SA, McLaren LC. Breastfeeding reduces risk of respiratory illness in infants. Am J Epidemiol. 1998 May 1;147(9):863-70. doi: 10.1093/oxfordjournals.aje.a009540. PubMed 9583717 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 12, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00005427
Lead sponsor
University of New Mexico
Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
First posted
May 26, 2000
Start date
Mar 1993
Completion
Feb 1995
Last update
Mar 12, 2024
View the source record on ClinicalTrials.gov ↗

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This study is terminated, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.

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