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CompletedNCT00005159Updated Aug 8, 2016

National Longitudinal Mortality Study (NLMS)

An observational study in Cardiovascular Diseases and Heart Diseases, sponsored by National Heart, Lung, and Blood Institute (NHLBI). Completed. Open to male participants aged Up to 100 Years. Per ClinicalTrials.gov, last updated 2016-08-08.

Sponsored by National Heart, Lung, and Blood Institute (NHLBI) · Observational

Study type
Observational
Ages
Up to 100 Years
Sex
Male
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Study summary

To estimate probabilities of death by cause for a representative United States population, according to age, sex, race, occupation, industry, income, education, residence, country of birth, calendar year, and a number of other demographic and epidemiologic factors. The representative population is derived from selected Bureau of the Census files and is matched to the National Death Index maintained by the National Center for Health Statistics. The Bureau of the Census provides the data processing, coding and management necessary to complete this objective.

Read the detailed description

BACKGROUND:

The current National Longitudinal Mortality Study began in 1983 with agreements with the Census Bureau which prepared baseline files from surveys representative of the United States and with the National Center for Health Statistics which prepared the National Death Index identifying deaths in the baseline populations. The baseline population of over one million persons has been matched to the NDI on several occasions, resulting in approximately 100,000 deaths occurring in 1979 to 1989. Using available data, an analysis was conducted relating socio-economic characteristics to subsequent mortality.

DESIGN NARRATIVE:

The NLMS is a national study of mortality over time among selected Census Bureau population samples numbering about 2.4 million. The census samples are matched to the National Death Index (NDI) maintained by the National Center for Health Statistics. The NDI is a file of all U.S. deaths since 1979 and is used to determine which individuals in the Current Population Surveys (CPS) have died. The samples are matched every other year to obtain deaths among these cohorts. Death certificates are then purchased from the states and coded for causes of death and other data. Mortality rates by age, sex, race, national origin, occupation, industry, income, education, state of residence and other factors are then obtained. The follow-up period begins with 1979, the first year covered by the NDI and ends with 1998. The total number of deaths for these cohorts is estimated to be about 250,000.

Census samples in the NLMS are being matched to the Centers for Medicare \& Medicaid Services (CMS) medicare database. Hospitalization, physician, outpatient, and other CMS data will be incorporated into the NLMS database for all participants meeting the Medicare age eligibility criteria. The study continues through December, 2009.

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Conditions studied

  • Cardiovascular Diseases
  • Heart Diseases
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In context

Cardiovascular Diseases

4,904 studies on the registry are indexed under Cardiovascular Diseases; 919 are open to participants now.

Browse Cardiovascular Diseases studies →

Lead sponsor

National Heart, Lung, and Blood Institute (NHLBI) is the lead sponsor of 1,117 studies on the registry; 71 are open to participants now.

Of its 57 completed or terminated interventional studies of FDA-regulated products, 49 (86%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Up to 100 Years
Sexes eligible
Male
Accepts healthy volunteers
No

Eligibility criteria

No eligibility criteria

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Study design

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Rogot E, Feinleib M, Ockay KA, Schwartz SH, Bilgrad R, Patterson JE. On the feasibility of linking census samples to the National Death Index for epidemiologic studies: a progress report. Am J Public Health. 1983 Nov;73(11):1265-9. doi: 10.2105/ajph.73.11.1265. PubMed 6625029 ↗
  • Rogot E, Schwartz SH, O'Conor KV, Olsen CL: The Use of Probabilistic Methods in Matching Census Samples of the National Death Index. 1983 Proceedings of the Section on Survey Research Methods, American Statistical Association, 319-324, 1983
  • Makuc D, McMillen M, Feinleib M, McMillen D, Schwartz S, Rogot E: An Overview of the U.S. National Longitudinal Mortality Study. 1984 Proceedings of the Section on Social Statistics, American Statistical Association, 1984
  • Johnson N, Rogot E, Glover C, Sorlie P, McMillen M: General Mortality Among Selected Census Bureau Sample Cohorts for 1979-1981. 1985 Proceedings of the Section on Survey Research Methods, American Statistical Association, 1985
  • Rogot E, Sorlie P, Johnson NH, Glover CS, Makuc D: Mortality by Cause of Death Among Selected Census Bureau Sample Cohorts for 1979-1981. 1985 Proceedings of the Section on Survey Research Methods, American Statistical Association, 1985
  • Rogot E, Sorlie P, Johnson NJ. Probabilistic methods in matching census samples to the National Death Index. J Chronic Dis. 1986;39(9):719-34. doi: 10.1016/0021-9681(86)90155-4. PubMed 3734026 ↗
  • Rogot E, Sorlie PD, Johnson NJ, Glover CS, and Treasure DW: A Mortality Study of One Million Persons by Demographic, Social and Economic Factors: 1979-1981 Follow-Up. U.S. National Longitudinal Mortality Study. First Data Book. DHHS, PHS, NIH Pub. No. 88-2896, p 307, 1988
  • Sorlie PD, Rogot E. Mortality by employment status in the National Longitudinal Mortality Study. Am J Epidemiol. 1990 Nov;132(5):983-92. doi: 10.1093/oxfordjournals.aje.a115741. PubMed 2239913 ↗
  • Rogot E, Sorlie PD, Johnson NJ. Life expectancy by employment status, income, and education in the National Longitudinal Mortality Study. Public Health Rep. 1992 Jul-Aug;107(4):457-61. PubMed 1641443 ↗
  • Sorlie PD, Johnson NJ, Backlund E, Bradham DD. Mortality in the uninsured compared with that in persons with public and private health insurance. Arch Intern Med. 1994 Nov 14;154(21):2409-16. PubMed 7979836 ↗
  • Rogot E, Sorlie PD, Johnson NJ, et al: A mortality study of 1.3 million persons by demographic, social, and economic factors: 1979-1985 follow-up. National Institutes of Health, Bethesda, Md; NIH Pub. No. 92-3297, 1992
  • Sorlie PD, Backlund E, Johnson NJ, Rogot E. Mortality by Hispanic status in the United States. JAMA. 1993 Nov 24;270(20):2464-8. PubMed 8031341 ↗
  • Rogot E, Sorlie PD, Backlund E. Air-conditioning and mortality in hot weather. Am J Epidemiol. 1992 Jul 1;136(1):106-16. doi: 10.1093/oxfordjournals.aje.a116413. PubMed 1415127 ↗
  • Sorlie PD, Rogot E, Johnson NJ. Validity of demographic characteristics on the death certificate. Epidemiology. 1992 Mar;3(2):181-4. doi: 10.1097/00001648-199203000-00018. PubMed 1576225 ↗
  • Backlund E, Sorlie PD, Johnson NJ. The shape of the relationship between income and mortality in the United States. Evidence from the National Longitudinal Mortality Study. Ann Epidemiol. 1996 Jan;6(1):12-20; discussion 21-2. doi: 10.1016/1047-2797(95)00090-9. PubMed 8680619 ↗
  • Sorlie PD, Backlund E, Keller JB. US mortality by economic, demographic, and social characteristics: the National Longitudinal Mortality Study. Am J Public Health. 1995 Jul;85(7):949-56. doi: 10.2105/ajph.85.7.949. PubMed 7604919 ↗
  • Smith MH, Anderson RT, Bradham DD, Longino CF Jr. Rural and urban differences in mortality among Americans 55 years and older: analysis of the National Longitudinal Mortality Study. J Rural Health. 1995 Fall;11(4):274-85. doi: 10.1111/j.1748-0361.1995.tb00425.x. PubMed 10153687 ↗
  • Preston SH, Elo IT. Are educational differentials in adult mortality increasing in the United States? J Aging Health. 1995 Nov;7(4):476-96. doi: 10.1177/089826439500700402. PubMed 10165966 ↗
  • Howard G, Anderson R, Sorlie P, Andrews V, Backlund E, Burke GL. Ethnic differences in stroke mortality between non-Hispanic whites, Hispanic whites, and blacks. The National Longitudinal Mortality Study. Stroke. 1994 Nov;25(11):2120-5. doi: 10.1161/01.str.25.11.2120. PubMed 7974531 ↗
  • Sorlie PD, Johnson NJ. Validity of education information on the death certificate. Epidemiology. 1996 Jul;7(4):437-9. doi: 10.1097/00001648-199607000-00017. PubMed 8793373 ↗
  • Sorlie P, Rogot E, Anderson R, Johnson NJ, Backlund E. Black-white mortality differences by family income. Lancet. 1992 Aug 8;340(8815):346-50. doi: 10.1016/0140-6736(92)91413-3. PubMed 1353813 ↗
  • Elo IT, Preston SH. Educational differentials in mortality: United States, 1979-85. Soc Sci Med. 1996 Jan;42(1):47-57. doi: 10.1016/0277-9536(95)00062-3. PubMed 8745107 ↗
  • Johnson NJ, Backlund E, Sorlie PD, Loveless CA. Marital status and mortality: the national longitudinal mortality study. Ann Epidemiol. 2000 May;10(4):224-38. doi: 10.1016/s1047-2797(99)00052-6. PubMed 10854957 ↗
  • Jackson SA, Anderson RT, Johnson NJ, Sorlie PD. The relation of residential segregation to all-cause mortality: a study in black and white. Am J Public Health. 2000 Apr;90(4):615-7. doi: 10.2105/ajph.90.4.615. PubMed 10754978 ↗
  • Muntaner C, Sorlie P, O'Campo P, Johnson N, Backlund E. Occupational hierarchy, economic sector, and mortality from cardiovascular disease among men and women. Findings from the National Longitudinal Mortality Study. Ann Epidemiol. 2001 Apr;11(3):194-201. doi: 10.1016/s1047-2797(00)00210-6. PubMed 11248583 ↗
  • Sorlie PD, Coady S, Lin C, Arias E. Factors associated with out-of-hospital coronary heart disease death: the national longitudinal mortality study. Ann Epidemiol. 2004 Aug;14(7):447-52. doi: 10.1016/j.annepidem.2003.10.002. PubMed 15301780 ↗
  • Anderson RT, Sorlie P, Backlund E, Johnson N, Kaplan GA. Mortality effects of community socioeconomic status. Epidemiology. 1997 Jan;8(1):42-7. doi: 10.1097/00001648-199701000-00007. PubMed 9116094 ↗
  • Howard G, Anderson R, Johnson NJ, Sorlie P, Russell G, Howard VJ. Evaluation of social status as a contributing factor to the stroke belt region of the United States. Stroke. 1997 May;28(5):936-40. doi: 10.1161/01.str.28.5.936. PubMed 9158628 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 8, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00005159
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
First posted
May 26, 2000
Start date
Jul 1983
Completion
Dec 2009
Last update
Aug 8, 2016
View the source record on ClinicalTrials.gov ↗

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