Yale University: Opioid-Related Disorders trials

The registry lists 104 Opioid-Related Disorders studies with Yale University as lead sponsor. 20 are open to participants now and 26 have results posted.

Early Phase 1 2Phase 1 11Phase 2 25Phase 3 7Phase 4 7No phase 56(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Cannabidiol in Opioid Use Disorder and Chronic Pain With BuprenorphineRecruitingNCT07886606Early Phase 1
• Characterization of CB1 Receptors Using [11-C]OMAR in Opioid Use DisorderRecruitingNCT07800520Phase 1
• Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 3RecruitingNCT07793383Not applicable
• EMS-Initiated BuprenorphineRecruitingNCT07475728
• A Clinical Trial of Telehealth Treatment for Opioid Use DisordersRecruitingNCT07362082Not applicable
• Acceptability and Feasibility of Extended-Release Subcutaneous Buprenorphine on a Mobile Pharmacy ClinicRecruitingNCT07176351Phase 4
• Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and RecoveryRecruitingNCT07115030Not applicable
• Opioid Use Disorder and PainRecruitingNCT06800703
• Adaptive Decision Support for Addiction Treatment MasterRecruitingNCT06799117Not applicable
• fMRI and Opioid AbstinenceRecruitingNCT06651333
• Combined THC and CBD for OUD and Chronic PainRecruitingNCT06544291Phase 2
• M2VA Pain Care PathwayRecruitingNCT06526143Not applicable
• Standard Versus High Dose ED-Initiated Buprenorphine InductionRecruitingNCT06494904Phase 3
• Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.RecruitingNCT06323824Phase 4
• Longitudinal Neural Fingerprinting of Opioid-use TrajectoriesRecruitingNCT06207162Not applicable
• Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)RecruitingNCT06160284Phase 1
• OMAR Opioid Use DisorderRecruitingNCT05683184Phase 1
• Expanding Medication-Assisted Therapies in Central AsiaRecruitingNCT05579470Not applicable
• Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved WomenRecruitingNCT05547048Phase 4
• Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) ScanningRecruitingNCT01730781
• Feasibility and Preliminary Efficacy of an Opioid Stewardship Program in Hospitalized Patients With Chronic PainCompletedNCT05370326Not applicableResults posted
• Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved PopulationsCompletedNCT05286879Not applicableResults posted
• Computer Based Treatment for Cognitive Behavioral Therapy and Cooperative Pain Education and Self-ManagementCompletedNCT05204576Not applicableResults posted
• Integrating Addiction Treatment and HIV Services Into Primary Care Clinics in UkraineCompletedNCT04927091Not applicableResults posted
• SafetyNet Program for Opioid Use Disorder (OUD)CompletedNCT04253782Not applicableResults posted
• Treatment of Pregnant Women With OUDCompletedNCT04240392Not applicableResults posted
• Neurofeedback in Individuals With Substance Use DisordersTerminatedNCT04188288Not applicableResults posted
• Coordinating Opioid Use Treatment Through Medical Management With Infection Treatment (Project COMMIT)CompletedNCT04180020Not applicableResults posted
• A Digital Intervention to Prevent Initiation of Opioid Misuse in Adolescents in School-based Health CentersCompletedNCT04109599Not applicableResults posted
• Clinical Decision Support to Implement ED-initiated Buprenorphine for OUDCompletedNCT03658642Not applicableResults posted
• Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PETCompletedNCT03527485Not applicableResults posted
• Addiction, HIV and Tuberculosis in Malaysian Criminal Justice SettingsCompletedNCT03089983Not applicableResults posted
• Opioid Use Disorder in the Emergency Department: CTN 0069CompletedNCT03023930Not applicableResults posted
• The Effects of Minocycline in Opioid-maintained PatientsCompletedNCT02359006Not applicableResults posted
• Buprenorphine Treatment for Opioid DependenceCompletedNCT02187198Phase 3Results posted
• Testosterone Replacement for Male Opioid Agonist Maintained PatientsCompletedNCT01873989Phase 1/2Results posted
• A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance TreatmentTerminatedNCT01802515Not applicableResults posted
• HIV, Buprenorphine, and the Criminal Justice SystemCompletedNCT01550341Not applicableResults posted
• Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice PopulationsCompletedNCT01246401Phase 1/2Results posted
• Models of Screening, Brief Intervention With a Facilitated Referral to Treatment (SBIRT) for Opioid Patients in the Emergency DepartmentCompletedNCT00913770Not applicableResults posted
• Clinical Trial of Integrated Treatment for Pain and Opioid DependenceCompletedNCT00634803Phase 1/2Results posted
• Effective Treatment of Hepatitis C in Substance UsersCompletedNCT00633243Not applicableResults posted
• Counseling for Primary Care Office-based BuprenorphineCompletedNCT00595764Phase 4Results posted
• Cocaine Withdrawal and Pharmacotherapy ResponseCompletedNCT00566969Not applicableResults posted
• Buprenorphine Maintenance vs. Detoxification in Prescription Opioid DependenceCompletedNCT00555425Phase 4Results posted
• Effectiveness of Lofexidine to Prevent Stress-Related Opiate Relapse During Naltrexone Treatment - 1CompletedNCT00142909Phase 2Results posted
• Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 2CompletedNCT07602218Not applicable
• Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 1CompletedNCT07549126Not applicable
• Adaptive Decision Support for Addiction Treatment (ADAPT) Factorial TrialCompletedNCT06793696Not applicable
• Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic PsychedelicsTerminatedNCT06624137
• Vitamin D in OUD: Exploration of Alterations on the Dopamine D2/D3 Receptor SystemCompletedNCT06261905Phase 1
• Telehealth Treatment for Opioid Use DisordersCompletedNCT05832879Not applicable
• Buprenorphine Integration Research and Community HealthActive, not recruitingNCT05668780Not applicable
• Neuroplasticity in Maternal Opioid Use Disorder (OUD)SuspendedNCT05495984Not applicable
• Safety, Tolerability and Pharmacokinetics of NYX-783 and Oxycodone DDI StudyCompletedNCT05447286Phase 1
• Pain Care at Home to Amplify Function (Pain CHAMP)Active, not recruitingNCT05333341Not applicable
• Developing e-Covery, an App-based Intervention to Support Individuals With Co-occurring Problem Alcohol and Opioid UseCompletedNCT05325788Not applicable
• Stepped Care for Patients to Optimize Whole RecoveryActive, not recruitingNCT05155163Not applicable
• Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the CommunityCompletedNCT04947475Not applicable
• Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support ServicesActive, not recruitingNCT04738825Not applicable
• Cannabidiol in Opioid Use Disorder and Chronic PainCompletedNCT04587791Early Phase 1
• Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social SupportCompletedNCT04309565Not applicable
• Emergency Department-Initiated Buprenorphine Validation Network TrialCompletedNCT04225598Phase 2
• Implementation of STTR Strategies Among People Who Inject Drugs in MalaysiaTerminatedNCT03987282Not applicable
• Patient Reported Outcomes for Opioid Use DisorderCompletedNCT03985163
• HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)CompletedNCT03583138
• Patient Driven Recovery With Nalmefene and CoachingCompletedNCT03279562Phase 1
• A Naturalistic Study of Adolescents and Young Adults in Treatment for Opioid DependenceCompletedNCT02718352
• Project BEST: Buprenorphine Entry Into Substance Abuse TreatmentCompletedNCT02583243
• Intervention of HIV, Drug Use and the Criminal Justice System in MalaysiaCompletedNCT02396979Phase 4
• Atomoxetine for ATS and Opioid Dependence During Buprenorphine Maintenance Treatment in MalaysiaCompletedNCT01863251Phase 2
• Computer-based Cognitive Behavioral Therapy for Risky Behaviors in Opioid Dependent PatientsCompletedNCT01645033Not applicable
• Yoga for Pain and Opioid DependenceCompletedNCT01590251Phase 1/2
• FMRI of Stress and Addictive DisordersCompletedNCT01558973
• Behavioral Drug and HIV Risk Reduction Counseling With MMT in ChinaCompletedNCT01389180Phase 3
• Naltrexone and Behavioral Drug and HIV Risk Reduction Counseling in RussiaCompletedNCT01389167Phase 3
• Cognitive-Behavioral Therapy for Pain and Opioid Dependence in Methadone Maintenance TreatmentCompletedNCT01334580Phase 1
• Study of Computer-Based Treatment for Drug DependenceCompletedNCT01315184Phase 2
• The Prevalence of HIV Drug Resistance and Transmission Risk in Opioid Agonist TreatmentCompletedNCT00857350
• Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM)CompletedNCT00798538Phase 4
• Behavioral Drug and HIV Risk Reduction Counseling in Methadone Patients in ChinaCompletedNCT00757744Phase 3
• Chronic Pain and Opioid Dependence Assessment and TreatmentCompletedNCT00727675Not applicable
• Testing a Primary Care Model for the Treatment of Opioid Dependence Using Long-acting Injectable Naltrexone (Vivitrol).WithdrawnNCT00675532Not applicable
• Prospective Cohort of Opiate Dependent Patients on Buprenorphine/Naloxone for MaintenanceCompletedNCT00622596Not applicable
• Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients.CompletedNCT00593125Phase 2
• Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine AbusersCompletedNCT00580827Not applicable
• Reducing Sex-Related HIV Risk Behaviors in Patients Receiving Treatment for Opioid DependenceCompletedNCT00548275Phase 2
• Drug Counseling and Abstinent-Contingent Take-Home Buprenorphine in MalaysiaCompletedNCT00539123Not applicable
• Brief Introductory Therapy for Opioid DependenceCompletedNCT00406484Phase 2
• HIV Risk Reduction and Drug Abuse Treatment in IranWithdrawnNCT00398008Phase 2
• HIV Risk Reduction and Drug Abuse Treatment in MalaysiaCompletedNCT00383045Phase 2
• Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1CompletedNCT00023283Phase 2
• Buprenorphine Maintenance Dose Schedule and Treatment Setting - 2CompletedNCT00000319Phase 2
• Combining Behavioral Treatment With Agonist Maintenance - 1CompletedNCT00000311Phase 3
• Novel Medications for Opiate Detoxification - 4CompletedNCT00000279Phase 2
• Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1CompletedNCT00000216Phase 3
• Buprenorphine Maintenance for Opioid Addicts - 3CompletedNCT00000204Phase 2
• Buprenorphine Maintenance for Opioid Addicts - 2CompletedNCT00000203Phase 2
• Buprenorphine Maintenance for Opioid Addicts - 1CompletedNCT00000202Phase 2
• Neurobiology of Opioid Dependence: 5 - 5WithdrawnNCT00000196Phase 2