Washington University School of Medicine: Depressive Disorder, Treatment-Resistant trials

The registry lists 13 Depressive Disorder, Treatment-Resistant studies with Washington University School of Medicine as lead sponsor. 3 are open to participants now and 7 have results posted.

Phase 1 4Phase 2 3Phase 4 2No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• The BAARD Study : Evaluating a Computerized Approach to Treatment Selection in Older Adults With Treatment Resistant Depression.Not yet recruitingNCT07810738Phase 2
• Disruptions of Brain Networks and Sleep by Electroconvulsive TherapyRecruitingNCT05905705
• NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain CircuitsRecruitingNCT02994433Phase 1
• KET-RO Plus RO DBT for Treatment Resistant DepressionCompletedNCT06138691Phase 1Results posted
• Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) ICompletedNCT04680910Phase 1Results posted
• Ketamine for Older Adults PilotCompletedNCT04504175Phase 4Results posted
• Inhaled Nitrous Oxide for Treatment-Resistant Depression: Optimizing Dosing StrategiesCompletedNCT03283670Phase 2Results posted
• Optimizing Outcomes of Treatment-Resistant Depression in Older AdultsCompletedNCT02960763Phase 4Results posted
• Treatment Resistant Depression (Pilot)CompletedNCT01179009Not applicableResults posted
• Dopaminergic Effects of Adjunctive Aripiprazole on the Brain in Treatment-Resistant DepressionCompletedNCT00953745Not applicableResults posted
• Dasatinib Plus Quercetin for Accelerated Aging in Mental DisordersActive, not recruitingNCT05838560Phase 2
• CET- REM (Correlating ECT Response to EEG Markers)Active, not recruitingNCT04451135Not applicable
• Adaptive tDCS for Treatment-Resistant MDDTerminatedNCT02942368Phase 1