Washington University School of Medicine: Breast Neoplasms trials

The registry lists 75 Breast Neoplasms studies with Washington University School of Medicine as lead sponsor. 18 are open to participants now and 22 have results posted.

Early Phase 1 4Phase 1 15Phase 2 30No phase 28(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Positron Emission Tomography (PET) Imaging of Chemotherapy-Induced CardiotoxicityNot yet recruitingNCT07838649Phase 1
• Navigation Interventions for Patients With Breast Cancer and High-risk Social Determinants of HealthRecruitingNCT07781800Not applicable
• Trastuzumab Deruxtecan and Lovastatin in HER2-low and Ultralow Advanced or Metastatic Breast CancerNot yet recruitingNCT07619365Phase 2
• Overcoming Racial Disparities in Screening MammographyNot yet recruitingNCT07549139Not applicable
• Precision Supplemental Imaging in Women With Dense BreastsRecruitingNCT07277738Not applicable
• ChatGPT & Surgeon Synergy: Redefining Breast Reconstruction Consultations for Enhanced Patient Engagement and SatisfactionRecruitingNCT06981208Not applicable
• Ovarian-Sparing Adaptive Radiotherapy in Young Adult WomenRecruitingNCT06904365
• WashU DIEP Flap Video and Patient Understanding ImprovementRecruitingNCT06864754Not applicable
• Ultra-Hypofractionated vs. Hypofractionated Radiation for Node-Positive Breast CancerRecruitingNCT06559540Phase 2
• Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone MetastasisRecruitingNCT06374459Phase 1/2
• BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast CancerRecruitingNCT05977036Not applicable
• COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical PatientsRecruitingNCT05972343
• NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast CancerRecruitingNCT05837455Phase 2
• Cryoablation vs Lumpectomy in T1 Breast CancersRecruitingNCT05505643Not applicable
• Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity TestingRecruitingNCT04968964Not applicable
• Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid TumorsRecruitingNCT04354064
• Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence ScoreRecruitingNCT02476786Phase 2
• Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer CellsRecruitingNCT00353483
• Implementing BREASTChoice Into PracticeCompletedNCT04491591Not applicableResults posted
• RANKL Inhibition and Mammographic Breast DensityActive, not recruitingNCT04067726Phase 2Results posted
• PROactive Evaluation of Function to Avoid CardioToxicityTerminatedNCT03862131Phase 2Results posted
• Optimizing Decision Making About Breast Reconstruction After Mastectomy: A Patient-Centered ApproachCompletedNCT03346161Phase 1Results posted
• Neoantigen DNA Vaccine Alone vs. Neoantigen DNA Vaccine Plus Durvalumab in Triple Negative Breast Cancer Patients Following Standard of Care TherapyTerminatedNCT03199040Phase 1Results posted
• PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast SurgeryCompletedNCT03084536Phase 2Results posted
• Alternative Dosing Schedule of Palbociclib in Metastatic Hormone Receptor Positive Breast CancerCompletedNCT03007979Phase 2Results posted
• Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast CancerTerminatedNCT02907918Phase 2Results posted
• Ultrasound and Near Infrared Imaging for Predicting and Monitoring Neoadjuvant TreatmentCompletedNCT02891681Not applicableResults posted
• MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived TumorsTerminatedNCT02669914Phase 2Results posted
• Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission TomographyCompletedNCT02455453Phase 2Results posted
• Tumor: Breast Ratio StudyCompletedNCT02216136Results posted
• Single Fraction High-Gradient Partial Breast Irradiation in Treating Patients With Low-Risk Stage 0-I Breast CancerCompletedNCT02076074Not applicableResults posted
• Effect of Trastuzumab on Disease Free Survival in Early Stage HER2-Negative Breast Cancer Patients With ERBB2 Expressing Disseminated Tumor CellsTerminatedNCT01779050Phase 2Results posted
• PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast CancerActive, not recruitingNCT01723774Phase 2Results posted
• Neratinib +/- Fulvestrant in Metastatic HER2 Non-amplified But HER2 Mutant Breast CancerCompletedNCT01670877Phase 2Results posted
• Goserelin and Letrozole or Anastrozole in Premenopausal Patients With Stage II-III Estrogen Receptor-Positive Breast CancerTerminatedNCT01368263Phase 2Results posted
• Neoadjuvant Platinum-based Chemoradiation Therapy for Locally Advanced Triple Negative Breast CancerTerminatedNCT01167192Phase 2Results posted
• Effect of Chemotherapy and Radiation Prior to Surgery for Triple Negative Breast CancerTerminatedNCT00603408Phase 2Results posted
• Partial Breast Irradiation (PBI) for Selected Patients With Early Breast CancerCompletedNCT00325598Phase 1/2Results posted
• Study of Physiological and High Dose Estradiol in the Treatment of Hormone Receptor Positive Metastatic Breast CancerCompletedNCT00324259Phase 2Results posted
• A Study of the Effects of Inhibiting Platelet Function on Circulating Cancer Cells in Breast Cancer PatientsTerminatedNCT00263211Phase 2Results posted
• HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed TherapyTerminatedNCT06844669Phase 2
• Mental and Cognitive Health and Physical Activity in the Perioperative Breast Cancer SettingCompletedNCT06595901
• Enhanced Assistance During Radiotherapy for Unmet Essential NeedsCompletedNCT06582849Not applicable
• Prehabilitation to Revolutionize Oncology: Telehealth Exercise for Cognitive Triumphs (The PROTECT Trial)CompletedNCT05716542Not applicable
• Utilizing Social Contacts to Facilitate Mammogram Screening Among African American WomenCompletedNCT05275361Not applicable
• A Low AGE (Advanced Glycation End-product) Dietary Intervention for Breast Cancer SurvivorsCompletedNCT05265715Not applicable
• Combination Liposomal Irinotecan and Pembrolizumab For Triple-Negative Breast Cancer (TNBC) With Brain Metastases (BM)WithdrawnNCT05255666Phase 2
• Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast CarcinomaActive, not recruitingNCT04849871Not applicable
• Epicutaneous Cryoimmunotherapy Combined With Pembrolizumab for Cutaneous Metastatic Breast CancerTerminatedNCT03982004Phase 1
• RANKL Inhibition and Breast Tissue BiomarkersCompletedNCT03629717Early Phase 1
• Three Fraction Accelerated Partial Breast Irradiation as the Sole Method of Radiation Therapy for Low-risk Stage 0 and I Breast CarcinomaCompletedNCT03612648Not applicable
• MCS110 Combined With Neoadjuvant Doxorubicin, Cyclophosphamide, and Weekly Paclitaxel in Patients With Hormone-Receptor Positive and HER2- Breast CancerWithdrawnNCT03285607Phase 1
• Mindful Movement in Women Receiving Adjuvant or Neoadjuvant Therapy for Breast CancerCompletedNCT03262831Not applicable
• Bright Light on Fatigue in Women Being Treated for Breast CancerCompletedNCT02658708Phase 1
• Shave Margins in Breast Conservation TherapyTerminatedNCT02462200Phase 2
• Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant ChemotherapyWithdrawnNCT02427581Phase 1
• Safety and Immunogenicity of a Personalized Polyepitope DNA Vaccine Strategy in Breast Cancer Patients With Persistent Triple-Negative Disease Following Neoadjuvant ChemotherapyCompletedNCT02348320Phase 1
• Fluorescence Imaging in Sentinel Lymph Node Biopsy for Breast Cancer and MelanomaCompletedNCT02316795Early Phase 1
• Safety and Immune Response to a Mammaglobin-A DNA Vaccine In Breast Cancer Patients Undergoing Neoadjuvant Endocrine TherapyActive, not recruitingNCT02204098Phase 1
• Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast CancerWithdrawnNCT01953445Phase 2
• Axillary Ultrasound With or Without Sentinel Lymph Node Biopsy in Detecting the Spread of Breast Cancer in Patients Receiving Breast Conservation TherapyTerminatedNCT01821768Not applicable
• LDE225 in Treating Patients With Stage II-III Estrogen Receptor- and HER2-Negative Breast CancerWithdrawnNCT01757327Phase 2
• FES-PET for Patients Treated on NCI Protocol 8762WithdrawnNCT01714128Not applicable
• Lapatinib With Trastuzumab in Treating Patients With HER2-Negative/HER2 Mutant Metastatic Breast CancerWithdrawnNCT01557764Phase 2
• BKM120 and Fulvestrant for Treating Postmenopausal Patients With Estrogen Receptor-Positive Stage IV Breast CancerCompletedNCT01339442Phase 1
• Assessment of Progesterone Receptors in Breast Carcinoma by Positron Emission Tomography (PET) Using Fluoro Furanyl Norprogesterone (FFNP)CompletedNCT00968409Phase 1
• Mammaglobin-A DNA Vaccine for Metastatic Breast CancerCompletedNCT00807781Phase 1
• Effect of Aromatase Inhibitors on Bones and GenesCompletedNCT00603967Not applicable
• Intensity Modulated Radiotherapy for Breast CancerCompletedNCT00594477Phase 1
• Testing of Different Methods for Determining Whether Breast Cancer Has Spread to the Lymph NodesCompletedNCT00360152Early Phase 1
• A Study to Determine the Clinical Significance of Molecular Detection of Breast Cancer in the Blood of Stage IV Breast Cancer PatientsCompletedNCT00355316Not applicable
• PTK and Letrozole in Post-menopausal Women With Advanced Breast CancerTerminatedNCT00263198Phase 2
• High Dose Vit D Musculoskeletal Symptoms & Bone Density in Anastrozole-Treated Breast Cancer With Marginal Vit D StatusCompletedNCT00263185Early Phase 1
• Evaluation of Chemotherapy Prior to Surgery With or Without Zometa for Women With Locally Advanced Breast CancerCompletedNCT00242203Phase 2
• Neoadjuvant Letrozole in Treating Postmenopausal Women With Estrogen-Receptor Positive and/or Progesterone-Receptor Positive Stage II, Stage IIIA, or Stage IIIB Breast CancerCompletedNCT00084396Phase 2