University of Chicago: Squamous Cell Carcinoma of Head and Neck trials

The registry lists 14 Squamous Cell Carcinoma of Head and Neck studies with University of Chicago as lead sponsor. 2 are open to participants now and 8 have results posted.

Phase 1 5Phase 2 10(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck CancerRecruitingNCT05526924Phase 1
• A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck CancerRecruitingNCT05420948Phase 2
• De-Escalation Therapy for Human Papillomavirus Negative DiseaseCompletedNCT03944915Phase 2Results posted
• Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior ImmunotherapyTerminatedNCT03463161Phase 2Results posted
• A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay StudyCompletedNCT02841748Phase 2Results posted
• BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck CancerTerminatedNCT02706691Phase 2Results posted
• PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck CancerCompletedNCT01816984Phase 1/2Results posted
• Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck LesionsCompletedNCT01414426Phase 2Results posted
• Study in Locally Advanced Squamous Cell Carcinoma of Head and NeckTerminatedNCT01133678Phase 2Results posted
• Phase II Study of Skin Toxicity Dosing of IRESSA (Gefitinib) in Squamous Cell Carcinoma of the Head and NeckCompletedNCT00519077Phase 2Results posted
• Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck CancerTerminatedNCT06110195Phase 1
• Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal CancerCompletedNCT04572100Phase 1
• Neoadjuvant Pembrolizumab + Epacadostat Prior to Curative Surgical Care for Squamous Cell Carcinoma of the Head and NeckWithdrawnNCT03325465Phase 2
• Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck CancerCompletedNCT01847326Phase 1