University Health Network, Toronto: Head and Neck Neoplasms trials

The registry lists 30 Head and Neck Neoplasms studies with University Health Network, Toronto as lead sponsor. 7 are open to participants now and 1 have results posted.

Phase 1 3Phase 2 3Phase 3 1No phase 24(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• SALI-10 Probiotic to Reduce Osteoradionecrosis and Dental Toxicity Following Radiation Therapy for Head and Neck CancerNot yet recruitingNCT07883005Phase 3
• Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)RecruitingNCT07524114
• Feasibility of Early Swallowing and Speech Intervention for Head and Neck Cancer Patients Treated SURGicallyRecruitingNCT06192771Not applicable
• Virtual Rehabilitation for Cancer SurvivorsRecruitingNCT05898789Not applicable
• Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)RecruitingNCT05403177
• Liquid Biopsy Evaluation and Repository Development at Princess MargaretRecruitingNCT03702309
• Ontario-wide Cancer TArgeted Nucleic Acid EvaluationRecruitingNCT02906943
• Physiological Flow of Liquids in Head and Neck Cancer Patients: A Pilot StudyCompletedNCT04112940Results posted
• Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell CarcinomaActive, not recruitingNCT04599309
• Breathomics as Predictive Biomarker for Checkpoint Inhibitor ResponseCompletedNCT04146064
• Carotid PET/MRI With DOTATATE in Patients Post Head and Neck Radiation TherapyCompletedNCT04040166Not applicable
• Rehabilitation Planning Consult Phase II TrialCompletedNCT03672799Not applicable
• A 3D Analysis of Mandibular Plating Strategies in Oromandibular Reconstruction.CompletedNCT03550053Not applicable
• PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiotherapy for Head and Neck CancerCompletedNCT03455608Not applicable
• Comparison of Endoscopic Visualization and CT Imaging of Head and Neck Cancers With Pathological Validation StudyCompletedNCT03380208
• Intraoperative Evaluation Using ICG and SPY Fluorescence to Prevent Wound Complications in Head and Neck Surgery.WithdrawnNCT03345732
• The Translational Research Image-Guided Operating Room (TRIGORA): Intraoperative 3D Imaging for Head & Neck Surgical PatientsCompletedNCT03345719
• Selection Pressure and Evolution Induced by Immune Checkpoint Inhibitors and Other Immunologic TherapiesCompletedNCT02724488
• Quantitative Endoscopy of H&NCompletedNCT02704169Phase 2
• Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot StudyCompletedNCT02678884Not applicable
• Feeding Tube in Cancer PatientsWithdrawnNCT02675673Not applicable
• Multi-Modality Imaging for Head & Neck Cancer Free Flap Design AssessmentTerminatedNCT02629029Not applicable
• Sentinel Lymph Node Mapping of Oral Cancer Using Near-Infrared Fluorescence ImagingCompletedNCT02478138Not applicable
• Comparison of Percutaneous Image-guided GastrostomiesCompletedNCT02053428Not applicable
• Optical Coherence Tomography for Monitoring Late Oral Radiation Toxicity After Radiotherapy of Head and Neck Cancer PatientsCompletedNCT01692600
• Goal Directed Fluid Therapy in Free Flap Reconstructive SurgeryCompletedNCT01129037Not applicable
• A Phase I Trial of Abraxane, Cisplatin and 5-Fluorouracil Along With Chemoradiotherapy in Advanced Head and Neck CancerCompletedNCT00731380Phase 1
• S-Frame CT Immobilization Masks For Patients Undergoing Radiation Therapy For Head and Neck CancerCompletedNCT00252473Phase 2
• Erlotinib and Cisplatin in Treating Patients With Recurrent or Metastatic Head and Neck CancerCompletedNCT00030576Phase 1/2
• EF5 Prior to Surgery or Biopsy in Patients With Breast, Prostate, or Cervical Cancer or High Grade Soft Tissue SarcomaTerminatedNCT00004261Phase 1