Sixth Affiliated Hospital, Sun Yat-sen University: Rectal Neoplasms trials

The registry lists 36 Rectal Neoplasms studies with Sixth Affiliated Hospital, Sun Yat-sen University as lead sponsor. 21 are open to participants now and 0 have results posted.

Phase 2 11Phase 3 3No phase 23(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• mFOLFOXIRI Plus Bevacizumab for Organ Preservation in Locally Advanced Rectal CancerNot yet recruitingNCT07817888Phase 2
• NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARCNot yet recruitingNCT07765667Phase 2
• A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)RecruitingNCT07669220Phase 2
• SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RCRecruitingNCT07549399Phase 3
• Improvement Effect of Dexamethasone Enema for Acute Radiation-induced Rectal InjuryNot yet recruitingNCT07548736Phase 2
• Preventive Efficacy of Bergmann Enema for Acute Radiation-induced Rectal Injury in Rectal Cancer Patients Undergoing Short-course RadiotherapyNot yet recruitingNCT07302126Phase 2
• Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB ExpressionRecruitingNCT07176182Phase 2
• Comprehensive Analysis of Gut Microbiota Signatures in Metastatic Colorectal CancerRecruitingNCT07154173
• Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)RecruitingNCT06958432Phase 2/3
• Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)RecruitingNCT06923345Phase 2
• Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal CancerNot yet recruitingNCT06751394Phase 2
• Application of Amide Proton Transfer-Weighted Imaging in Predicting Pathological Complete Response After Neoadjuvant Therapy of Rectal CancerRecruitingNCT06719414
• Preoperative (Chemo)Radiotherapy for Locally Recurrent Rectal CancerNot yet recruitingNCT06617052
• Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal CancerRecruitingNCT05943444Not applicable
• Effects of Different Treatment for Anorectal Function of Patients With Rectal CancerNot yet recruitingNCT05671809
• Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRIRecruitingNCT05523245
• Complete Versus Partial Preservation of Denonvilliers' Fascia on Urogenital Function in Locally Advanced Rectal CancerRecruitingNCT04672603Not applicable
• Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal CancerRecruitingNCT04643041Not applicable
• Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal CancerNot yet recruitingNCT03975049Phase 3
• Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapyRecruitingNCT03587480Not applicable
• Proximally Extended Resection for Rectal Cancer After Neoadjuvant ChemoradiotherapyRecruitingNCT02649647Not applicable
• SCRT+mFOLFOX6+PD-1 Antibody and Targeted Therapy for High-Risk pMMR/MSS Rectal CancerCompletedNCT06908031Phase 2
• Prognostic Value of PARS Classification for Locally Recurrent Rectal CancerCompletedNCT06808308
• Assessment of Efficacy of Neoadjuvant Therapy in Locally Advanced Rectal CancerCompletedNCT06314737
• Development and Validation of The Post-RT LARS Prediction Model (PORTLARS)CompletedNCT05129215
• Management of LLN Metastasis in Locally Advanced Rectal Cancer: A Prospective Radiation Dose Escalation StudyStatus unknownNCT04991090Not applicable
• TRUS-FNA For The Prediction Of pCR After Neoadjuvant Treatment In Rectal CancerCompletedNCT04939103
• Post-Neoadjuvant Treatment MRI Based AI System to Predict pCR for Rectal CancerStatus unknownNCT04278274
• Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal CancerStatus unknownNCT04273477
• RadioPathomics Artificial Intelligence Model to Predict Tumor Regression Grading in Locally Advanced Rectal CancerStatus unknownNCT04273451
• RadioPathomics Artificial Intelligence Model to Predict nCRT Response in Locally Advanced Rectal CancerCompletedNCT04271657
• "Cross" Closure for Reconstructing the Perineal Wound of Abdominoperineal ResectionStatus unknownNCT03731754Not applicable
• Low or High Ligation of the IMA With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic SurgeryStatus unknownNCT03013153Not applicable
• Validate the Dosimetric Parameters That Correlate With Acute Hematologic Toxicity (HT) in Patients With Rectal CancerStatus unknownNCT02630056
• Detection of CTCs in Stage III Rectal Cancer Patients Undergoing Neoadjuvant TherapyStatus unknownNCT02554448Not applicable
• Neoadjuvant Chemoradiation With Bevacizumab for Chinese Rectal Cancer PatientsCompletedNCT01554059Phase 2