Shanghai Mental Health Center: Depressive Disorder, Major trials

The registry lists 38 Depressive Disorder, Major studies with Shanghai Mental Health Center as lead sponsor. 10 are open to participants now and 0 have results posted.

Phase 1 1Phase 2 6Phase 3 1Phase 4 7No phase 23(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Precision Closed-loop Brain-Computer Interface Neuromodulation for Treatment-Resistant DepressionNot yet recruitingNCT07783906Not applicable
• Home-Based Wearable rTMS Therapy for Moderate to Severe DepressionNot yet recruitingNCT07775586Not applicable
• Tracking Risk in Adolescents and Children for Early Identification of Common Mental DisordersNot yet recruitingNCT07744490
• iMORE+ Study: A Multi-Omics Cohort Study of Major Depressive DisorderNot yet recruitingNCT07735143
• Multimodal Pharmacological Study of Clinical Cohorts for Major Depressive DisorderNot yet recruitingNCT07602153
• Non-invasive BCI and Application Verification for Depressed PeopleRecruitingNCT06417437Phase 4
• Effectiveness of MST Versus ECT for Major Depressive EpisodeRecruitingNCT06409325Not applicable
• Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation TreatmentRecruitingNCT06385405Not applicable
• Assessing Dopamine Transporter Occupancy in the Patients With Depression Brain With Toludesvenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)RecruitingNCT06026917Phase 4
• Model-based Defining of Subtypes of Depression and Optimal Treatment: an Integrated Techniques Module.RecruitingNCT04518592
• Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)CompletedNCT05905120Phase 1
• A Trial of Enhanced Versus Standard Measurement-Based Care Implementation for DepressionStatus unknownNCT05577494
• Multi-factor Model Constraction for Early Warning and Diagnosis of MDDStatus unknownNCT05529576Phase 4
• Enhanced Measurement-Based Care Effectiveness for Depression (EMBED) StudyStatus unknownNCT05527951Not applicable
• Efficacy and Safety of Light Therapy in the Treatment of Non-seasonal Depressive Disorder in Chinese PopulationStatus unknownNCT05499117Not applicable
• A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive DisorderStatus unknownNCT05148169Phase 4
• A Comparative Study on Efficacy and Safety of add-on Sulforaphane or rTMS to Escitalopram for Major Depressive Disorder With Poor Response to Initial TreatmentStatus unknownNCT05145270Phase 4
• A Study of Xiongdan Wan Treating DepressionCompletedNCT05136365Phase 2
• The Role of Neuromodulation Technique In Depression DisorderStatus unknownNCT05047159Not applicable
• Quality of Life in Chinese Working and School Age Population With MDDStatus unknownNCT04986124
• PKC as Serum Biomarkers for DepressionStatus unknownNCT04531423Not applicable
• Optimization of Diagnosis and Treatment of Depression Based on Multidimensional Clinical Assessment ClassificationStatus unknownNCT04528628Not applicable
• Bear Bile Pill as add-on the Treatment of MDDStatus unknownNCT04509882Phase 2
• Comparison of Anyu Peibo With Placebo in Treatment of MDD in ChinaStatus unknownNCT04210973Phase 3
• A Study of Individualized Diagnosis and Treatment for Major Depressive Disorder With Atypical FeaturesStatus unknownNCT04209166Not applicable
• A Kynurenine Pathway-based Molecular Imaging Study of Individualized Diagnosis and Treatment for Major Depressive DisorderStatus unknownNCT04208932
• The Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive DepressionStatus unknownNCT04156425Not applicable
• Study on the Effect of PRKCB1 Modulating Inflammatory Factors and the Role for Developing Major Depressive DisorderStatus unknownNCT03899194Not applicable
• The Study of Mindfulness-based Cognitive Therapy and Major Depressive DisorderStatus unknownNCT03558256Not applicable
• Simplified Cognitive Behavioral Therapy for Generalized Anxiety Disorder and DepressionStatus unknownNCT03329287Not applicable
• Multi-Dimensional Diagnosis,Individualized Therapy,and Management Technique for Major Depressive Disorder:Based on Clinical and Pathological CharacteristicsStatus unknownNCT03219008Phase 4
• Comparison of Anyu Peibo With Placebo in Treatment of MDD，ⅡbCompletedNCT03183505Phase 2
• Relapse Predicting Model for First Episode DepressionStatus unknownNCT02942251Not applicable
• Comparison of Yuxintine With Placebo in Treatment of MDDStatus unknownNCT02395263Phase 2
• Comparison of Anyu Peibo With Placebo in Treatment of MDDCompletedNCT02380066Phase 2
• Comparison of Orcinoside With Placebo in Treatment of MDDCompletedNCT02191384Phase 2
• The Efficacy And Cognitive Impairment Of Modified Electroconvulsive TherapyCompletedNCT02066077Not applicable
• Algorithm Guided Treatment Strategies for Major Depressive DisorderStatus unknownNCT01764867Phase 4