Pfizer: Neoplasm Metastasis trials

The registry lists 48 Neoplasm Metastasis studies with Pfizer as lead sponsor. 6 are open to participants now and 24 have results posted.

Phase 1 25Phase 2 12Phase 3 11No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Learn About the Study Medicine Called PF-08098488 in People With Advanced Solid Tumors.RecruitingNCT07903415Phase 1
• Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell CancerRecruitingNCT07227415Phase 1/2
• Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal CancerRecruitingNCT07222800Phase 3
• Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung CancerRecruitingNCT07222566Phase 3
• A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and FatigueRecruitingNCT06989437Phase 2/3
• Pre-approval Single-patient Expanded Access for Talazoparib (PF-06944076)AvailableNCT05650476
• Study to Compare Overall Survival in Medicare Patients With Metastatic Breast Cancer Treated With a Medicine Called Palbociclib in Combination With Aromatase Inhibitor and Aromatase Inhibitor by Itself.CompletedNCT06086340Results posted
• Real World Evidence Study on Metastatic Prostate Cancer in the Pirkanmaa Hospital District in FinlandCompletedNCT05701007Results posted
• Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid TumorsTerminatedNCT04628780Phase 1Results posted
• Study of Immunotherapy (Sasanlimab) in Combination With Targeted Therapies in People With Advanced Non-small Cell Lung Cancer (NSCLC) (Landscape 1011 Study)TerminatedNCT04585815Phase 1/2Results posted
• PF-06952229 Treatment in Adult Patients With Advanced Solid TumorsTerminatedNCT03685591Phase 1Results posted
• Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566CompletedNCT02315066Phase 1Results posted
• A Study Of Palbociclib (PD-0332991) + Letrozole VS. Placebo+ Letrozole For 1st Line Treatment Of Asian Postmenopausal Women With ER+/HER2- Advanced Breast Cancer [PALOMA-4]CompletedNCT02297438Phase 3Results posted
• A Study Of PF-06647020 For Adult Patients With Advanced Solid TumorsCompletedNCT02222922Phase 1Results posted
• Evaluation Of The Impact Of A Call Center In Management Of Metastatic And/Or Advanced Renal Cell Carcinoma Patients Treated With Sunitinib (Sutent) In First LineCompletedNCT02187042Results posted
• A Study Of PF-06664178 In Patients With Advanced Solid TumorsTerminatedNCT02122146Phase 1Results posted
• A Study Of PF-06647263 In Patients With Advanced Solid TumorsTerminatedNCT02078752Phase 1Results posted
• A Study Of PF-05212384 In Combination With Other Anti-Tumor Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm (TNBC)CompletedNCT01920061Phase 1Results posted
• Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant MelanomaCompletedNCT01909453Phase 3Results posted
• A Study Of PF-06263507 In Patients With Advanced Solid TumorsTerminatedNCT01891669Phase 1Results posted
• ARCHER1050: A Study of Dacomitinib vs. Gefitinib in 1st-Line Treatment Of Advanced NSCLC.CompletedNCT01774721Phase 3Results posted
• Study Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive MelanomaCompletedNCT01763164Phase 3Results posted
• A Study of Palbociclib (PD-0332991) + Letrozole vs. Letrozole For 1st Line Treatment Of Postmenopausal Women With ER+/HER2- Advanced Breast Cancer (PALOMA-2)CompletedNCT01740427Phase 3Results posted
• A Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant MelanomaCompletedNCT01436656Phase 1Results posted
• A Study Of Two Dual PI3K/mTOR Inhibitors, PF-04691502 And PF-05212384 In Patients With Recurrent Endometrial CancerTerminatedNCT01420081Phase 2Results posted
• Non-Interventional Study Of Indian Patients With Advanced Renal Cell Cancer Receiving Therapy With SutentCompletedNCT00836745Results posted
• A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy RegimenCompletedNCT00769067Phase 2Results posted
• A Study Of Tanezumab as Add-On Therapy to Opioid Medication In Patients With Pain Due To Cancer That Has Spread To BoneCompletedNCT00545129Phase 2Results posted
• Temsirolimus Versus Sorafenib As Second-Line Therapy In Patients With Advanced RCC Who Have Failed First-Line SunitinibCompletedNCT00474786Phase 3Results posted
• Study Evaluating SKI-606 (Bosutinib) In Subjects With Breast CancerCompletedNCT00319254Phase 2Results posted
• A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced CancersTerminatedNCT06870487Phase 1
• A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.TerminatedNCT06546553Phase 1
• A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In CombinationTerminatedNCT06448364Phase 1
• PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid TumorsTerminatedNCT05233436Phase 1
• Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.CompletedNCT04881045Phase 1
• Study of PF-07265807 in Participants With Metastatic Solid Tumors.TerminatedNCT04458259Phase 1
• Efficacy and Safety Study of Enzalutamide in Combination With Paclitaxel Chemotherapy or as Monotherapy Versus Placebo With Paclitaxel in Patients With Advanced, Diagnostic-Positive, Triple-Negative Breast CancerWithdrawnNCT02929576Phase 3
• Safety Study of SEA-CD40 in Cancer PatientsTerminatedNCT02376699Phase 1
• Study of WNT974 in Combination With LGX818 and Cetuximab in Patients With BRAF-mutant Metastatic Colorectal Cancer (mCRC) and Wnt Pathway MutationsCompletedNCT02278133Phase 1/2
• A Safety Study of SGN-LIV1A in Breast Cancer PatientsCompletedNCT01969643Phase 1
• A Study of ARRY-382 in Patients With Selected Advanced or Metastatic CancersCompletedNCT01316822Phase 1
• A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic CancerCompletedNCT00736372Phase 1
• A Safety And Efficacy Study Of The Combination Of Oral PF-00299804 And Intravenous CP-751,871 Given Every 3 WeeksCompletedNCT00728390Phase 1
• A Research Study of CP-724,714 in Patients With HER2 Overexpressing Metastatic Breast CancerTerminatedNCT00102895Phase 2
• Study Evaluating CCI-779 and Letrozole in Post-menopausal Women With Breast CancerTerminatedNCT00083993Phase 3
• Study in Women With Metastatic Breast Cancer Whose Cancer Has Gotten Worse After Anthracycline and Taxane TherapyCompletedNCT00067314Phase 2
• For Prevention of Diarrhea in Patients Diagnosed With Metastatic Colorectal Cancer Treated With ChemotherapyTerminatedNCT00037180Phase 2
• Safety And Efficacy Study Of The Combination Of CpG 7909 And Herceptin In Patients With Metastatic Breast CancerCompletedNCT00031278Phase 1/2