Novo Nordisk A/S: Obesity trials

The registry lists 175 Obesity studies with Novo Nordisk A/S as lead sponsor. 49 are open to participants now and 32 have results posted.

Phase 1 67Phase 2 12Phase 3 57Phase 4 3No phase 37(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Semaglutide Health Outcomes and Patient Adherence in AustraliaNot yet recruitingNCT07881770
• A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide MedicationRecruitingNCT07868354Phase 1
• A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or ObesityNot yet recruitingNCT07861100Phase 3
• A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide MedicationRecruitingNCT07855133Phase 1
• A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body WeightNot yet recruitingNCT07845578Phase 1
• AMAZE 10: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People in Japan With Excess Body Weight Lose WeightRecruitingNCT07822061Phase 3
• A Research Study Looking at the Effect of Timing of Meal After Dosing and Water Volume at Dosing on How the Medicine Zenagamtide is Taken up by the Body of Participants With Overweight or ObesityRecruitingNCT07815067Phase 1
• Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body WeightRecruitingNCT07770841Phase 3
• A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or ObesityRecruitingNCT07767175Phase 1
• A Research Study to See How NNC0487-0111 Affects the Body's Energy Use After a Weight Loss in Adults Living With Overweight or Obesity, Compared to a Low-calorie Diet or PlaceboRecruitingNCT07757087Phase 1
• A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body WeightRecruitingNCT07745504Phase 3
• AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose WeightRecruitingNCT07720271Phase 3
• A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body WeightRecruitingNCT07710768Phase 1
• A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become PregnantRecruitingNCT07710729Phase 1
• A Study to See How Safe a New Medicine (NNC6022-0004) is in Healthy People and People Living With ObesityRecruitingNCT07693868Phase 1
• Prevalence and Overlap of Cardiovascular, Kidney, and Metabolic Diseases in Korea: A Population-based StudyEnrolling by invitationNCT07673822
• A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to SemaglutideRecruitingNCT07668414Phase 3
• AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose WeightNot yet recruitingNCT07668401Phase 3
• Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse EventsRecruitingNCT07607587Phase 1
• A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or ObesityRecruitingNCT07597018Phase 1
• A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in People With Reduced Liver Function and Normal Liver FunctionNot yet recruitingNCT07587710Phase 1
• A Research Study Investigating the Effect of NNC0497-0040 in Healthy Participants, Participants With Overweight or Obesity, and Participants With Type 1 Diabetes With Overweight or ObesityRecruitingNCT07578584Phase 1
• AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaRecruitingNCT07571109Phase 3
• AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaRecruitingNCT07571005Phase 3
• A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and ObesityRecruitingNCT07567001Phase 3
• A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or ObesityRecruitingNCT07566390Phase 1
• A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightRecruitingNCT07564414Phase 3
• A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or ObesityRecruitingNCT07557953Phase 1
• AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightRecruitingNCT07533175Phase 3
• Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)RecruitingNCT07527195Phase 1
• AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce PainRecruitingNCT07509307Phase 3
• A Research Study Looking at How NNC0487-0111 Affects Food Intake, Appetite and Metabolism After Meals in People With ObesityRecruitingNCT07508020Phase 1
• A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce PainRecruitingNCT07481630Phase 3
• A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or ObesityRecruitingNCT07437079Phase 1
• A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or ObeseRecruitingNCT07411560Phase 1
• AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightNot yet recruitingNCT07400107Phase 3
• A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or ObesityRecruitingNCT07395687Phase 2
• AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose WeightRecruitingNCT07339423Phase 3
• WEgovy Real World Assessment of Weight Loss in KoreaEnrolling by invitationNCT07280221
• A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body WeightRecruitingNCT07253285Phase 3
• Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)RecruitingNCT07225816Phase 1
• Characteristics and Treatment Experiences of Individuals Using Injectable Semaglutide for Weight Management, a Cross-sectional Time-series Analysis, Multi-country Study.Enrolling by invitationNCT07154238
• Safety Follow-up Study of Participants Dosed With INV-347 in Study INV-CL-108RecruitingNCT07153172Phase 1
• A Two-year Prospective, Observational Study of Wegovy in Real-world Clinical PracticeEnrolling by invitationNCT07055607
• A Multicentre, Prospective, Single-arm, Non-interventional Regulatory Post-marketing Surveillance (rPMS) Study to Investigate the Safety and Effectiveness of Wegovy® (Semaglutide) in Patients With Obesity and Patients With Overweight in Routine Clinical Practice in KoreaEnrolling by invitationNCT07018544
• The Role of the Amylin Analogue Cagrilintide in Bone MetabolismRecruitingNCT07010432Phase 1
• Cities for Better Health Childhood Obesity Prevention InitiativeEnrolling by invitationNCT06855563Not applicable
• A Study to Evaluate Safety of Exposure to Wegovy During PregnancyEnrolling by invitationNCT05872022
• A Study to Evaluate the Safety of Exposure to Wegovy During PregnancyEnrolling by invitationNCT05503927
• A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight RangeCompletedNCT06041217Phase 3Results posted
• A Research Study to See How Semaglutide Helps People With Excess Weight and Type 2 Diabetes Lose WeightCompletedNCT05649137Phase 3Results posted
• A Research Study to See How Semaglutide Helps People With Excess Weight, Lose Weight (STEP UP)CompletedNCT05646706Phase 3Results posted
• A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in AmericaCompletedNCT05579249Phase 4Results posted
• Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in People Who Have a Body Weight Above the Healthy RangeCompletedNCT05564117Phase 3Results posted
• A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE)CompletedNCT05514535Phase 3Results posted
• Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in East Asian People Who Are Overweight or Living With ObesityCompletedNCT05132088Phase 3Results posted
• Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee OsteoarthritisCompletedNCT05064735Phase 3Results posted
• Research Study Looking at How Well Semaglutide Works in People Living With Obesity and PrediabetesCompletedNCT05040971Phase 3Results posted
• Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in People Who Are Overweight or Living With Obesity (OASIS 1)CompletedNCT05035095Phase 3Results posted
• Research Study Investigating How Well Semaglutide Works in People From Thailand and South Korea Living With ObesityCompletedNCT04998136Phase 3Results posted
• A Research Study to Investigate How Well NNC0165-1875 in Combination With Semaglutide Works in People With ObesityCompletedNCT04969939Phase 2Results posted
• Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and ObesityCompletedNCT04788511Phase 3Results posted
• Research Study of How Well Semaglutide Works in People Living With Overweight or Obesity.CompletedNCT04251156Phase 3Results posted
• A Study Comparing the Injection Site Pain Experience After the Injection of Semaglutide B and Semaglutide D With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and ObesityCompletedNCT04143945Phase 2Results posted
• A Research Study on How Well Semaglutide Works in Adolescents With Overweight or ObesityCompletedNCT04102189Phase 3Results posted
• Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or ObesityCompletedNCT04074161Phase 3Results posted
• A Study Comparing the Injection Site Pain Experience After the Injection of 2 Different Solutions of Semaglutide With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and ObesityCompletedNCT04007107Phase 2Results posted
• A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic SteatohepatitisTerminatedNCT04004325Phase 1/2Results posted
• Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.CompletedNCT03856047Phase 2Results posted
• STEP 6: Research Study Investigating How Well Semaglutide Works in People Living With Overweight or ObesityCompletedNCT03811574Phase 3Results posted
• Real World Effectiveness of Combining an Employer-based Weight Management Program With Medication for Chronic Weight Management in Employees With ObesityCompletedNCT03799198Phase 4Results posted
• Two-year Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03693430Phase 3Results posted
• Research Study to Look at How Well Semaglutide is at Lowering Weight When Taken Together With an Intensive Lifestyle ProgramCompletedNCT03611582Phase 3Results posted
• Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or ObesityCompletedNCT03574597Phase 3Results posted
• Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or ObesityCompletedNCT03552757Phase 3Results posted
• Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03548987Phase 3Results posted
• STEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or ObesityCompletedNCT03548935Phase 3Results posted
• Effect and Safety of Liraglutide 3.0 mg as an Adjunct to Intensive Behaviour Therapy for Obesity in a Non-specialist SettingCompletedNCT02963935Phase 3Results posted
• Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal InsulinCompletedNCT02963922Phase 3Results posted
• Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects With ObesityCompletedNCT02918279Phase 3Results posted
• Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetesCompletedNCT01272219Phase 3Results posted
• Real-World Patient and Physician Experience With Semaglutide Across Six Emerging MarketsCompletedNCT07850765
• A Retrospective Real-World Cohort StudyActive, not recruitingNCT07781371
• A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityActive, not recruitingNCT07639021Phase 2
• Weight Loss in Adults Using Semaglutide (Real-world Study)CompletedNCT07627074
• A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body WeightCompletedNCT07605052Phase 1
• A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body WeightActive, not recruitingNCT07525791Phase 1
• AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight LossActive, not recruitingNCT07503210Phase 3
• Current Status of Cardiovascular Diseases in Chinese Overweight/ Obesity Population: An Epidemiological Study (COPE）CompletedNCT07358052
• A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightWithdrawnNCT07357766Phase 3
• Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With CagrilintideActive, not recruitingNCT07220759Phase 3
• Weight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideActive, not recruitingNCT07220642Phase 3
• A Research Study on How Well Different Doses of the Medicine NNC0662-0419 Help People Living With Overweight or ObesityActive, not recruitingNCT07184632Phase 2
• A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to DietActive, not recruitingNCT07184086Phase 1
• A Master Protocol for Semaglutide Effects on Cardiovascular and Obesity-related Outcomes in People With Overweight or Obesity in the Real WorldCompletedNCT07141914
• A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants When Injected Under the Skin.CompletedNCT07121153Phase 1
• A Research Study on How a Dose of NNC0662-0419 Works in Japanese, Chinese and Non-Asian Participants Living With Overweight or ObesityCompletedNCT07101783Phase 1
• A Non-interventional Study Investigating Semaglutide in Combination With Lifestyle-based Modifications for the Management of Obesity in Real-World Clinical Practice in Germany (WeGo Real Germany).TerminatedNCT07081178
• A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termActive, not recruitingNCT07011667Phase 3
• A Research Study of the New Medicine NNC0519-0130 in Male Chinese Participants Living With Excess Body WeightCompletedNCT07004322Phase 1