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Not yet recruitingNCT07881770SHAPED-AUUpdated Oct 19, 2026

Semaglutide Health Outcomes and Patient Adherence in Australia

An observational study in Overweight and Obesity, sponsored by Novo Nordisk A/S. Not yet recruiting at 1 site in Australia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-19.

Sponsored by Novo Nordisk A/S · Observational

Updated Oct 19, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
10,000
Ages
18 Years and older
Sex
All
01

Study summary

This observational study aims to generate real-world evidence on the use of semaglutide in adults with overweight or obesity receiving care through a digital weight loss service (DWLS) programme in Australia. The study will evaluate treatment patterns, adherence, quality of life, safety, and other health outcomes associated with semaglutide use in routine clinical practice. Information will be collected from data generated during standard clinical care, and no study-specific treatment or procedures will be required.

02

Conditions studied

  • Overweight
  • Obesity
03

In context

Overweight

3,767 studies on the registry are indexed under Overweight; 863 are open to participants now.

This study's planned enrollment of 10,000 is above the median of 150 across 443 observational studies indexed under Overweight.

Browse Overweight studies →

Lead sponsor

Novo Nordisk A/S is the lead sponsor of 1,400 studies on the registry; 102 are open to participants now.

Of its 204 completed or terminated interventional studies of FDA-regulated products, 98 (48%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

This study will recruit individuals who are receiving semaglutide for the management of overweight or obesity and who are enrolled in one of the Eucalyptus Digital Weight Loss Service (DWLS) programmes.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Willing and able to provide informed consent
  • Greater than or equal to (>=) 18 years of age at time of informed consent
  • Body Mass Index (BMI) >= 27 kg/m2 and have >= 1 excess weight-related comorbidity OR BMI >= 30 kg/m2
  • Eligible to be prescribed semaglutide for the management of overweight or obesity
  • Have provided at least one weight measurement within 30 days of index date
  • Enrolled in existing Eucalyptus DWLS programme.

Exclusion criteria

Exclusion Criteria:

  • Presence of a documented refusal to participate in research.
  • Previous reported use of GLP-1 RA in the 3-month period before index date.
  • Are currently taking another obesity medication i.e. medication indicated for weight management treatment.
  • Any prior irreversible bariatric surgery for weight management
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
10,000 participants (estimated)
Patient registry
No

Groups and cohorts

  • Semaglutide Cohort

    Adults with overweight or obesity who will initiate semaglutide as part of routine clinical care through a digital weight management programme in Australia and will be followed for up to 12 months. Semaglutide will be prescribed by healthcare professionals according to routine clinical practice for the management of overweight or obesity.

    Drug: Semaglutide

Interventions

  • All decisions regarding treatment will be made at the sole discretion of the treating HCP in accordance with their usual practices. No study medication will be provided as part of the study.

06

What researchers measure

Primary outcomes

  1. Absolute change in body weight from baseline

    Measured in kilograms (kg).

    Time frame: 12 months (365 days ±14 days)

  2. Percentage change in body weight from baseline

    Measured in percent (%) change from baseline.

    Time frame: 12 months (365 days ±14 days)

07

Study locations

1 site
  • Novo Nordisk Investigational site
    Sydney, 2000, Australia
08

References and documents

Individual participant data

Plan to share: Yes — According to the Novo Nordisk disclosure commitment on novonordisk-trials.com

Data sharing details ↗ · novonordisk-trials.com

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Oct 2026; primary completion for Feb 2028, 16 months later.

Of 164 observational studies under Overweight, half reached primary completion within 38 months of starting (the median), counting those still running; a quarter within 15 and three quarters within 98. This study's planned 16 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 13, 2026
First posted
Oct 19, 2026
StartEst.
Oct 13, 2026
Primary completionEst.
Feb 28, 2028
CompletionEst.
Feb 28, 2028
Last update
Oct 19, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 19, 2026
Show all 1 update
  1. Oct 19, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07881770
Lead sponsor
Novo Nordisk A/S
Collaborators
Eucalyptus Services Pty Ltd
Responsible party
Sponsor
First posted
Oct 19, 2026
Start date
Oct 13, 2026 (estimated)
Primary completion
Feb 28, 2028 (estimated)
Completion
Feb 28, 2028 (estimated)
Last update
Oct 19, 2026

Study contacts

Novo Nordisk
Contact
clinicaltrials@novonordisk.com
(+1) 866-867-7178
Clinical Transparency (dept. 2834)
study director · Novo Nordisk A/S

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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