New York State Psychiatric Institute: Depressive Disorder, Major trials

The registry lists 37 Depressive Disorder, Major studies with New York State Psychiatric Institute as lead sponsor. 1 are open to participants now and 24 have results posted.

Phase 1 3Phase 2 6Phase 3 5Phase 4 20No phase 7(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal ThoughtsNot yet recruitingNCT07139106Phase 4
• Antidepressant Response in Older Adults With Comorbid PTSD and MDDTerminatedNCT04697693Phase 4Results posted
• Ketamine Treatment Effects on Synaptic Plasticity in DepressionCompletedNCT04091971Phase 4Results posted
• Contact: Developing New Clinical Management StrategiesCompletedNCT03812588Phase 4Results posted
• L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older AdultsTerminatedNCT03761030Phase 4Results posted
• Flavanol Augmentation for Antidepressant Non-Responsive Late Life DepressionTerminatedNCT02943096Not applicableResults posted
• A Study of L-DOPA for Depression and Slowing in Older AdultsCompletedNCT02744391Phase 4Results posted
• Developing New Clinical Management StrategiesCompletedNCT02082392Phase 4Results posted
• Imaging Dopamine Release in DepressionCompletedNCT02033369Phase 4Results posted
• Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older AdultsCompletedNCT01973283Phase 4Results posted
• Mechanisms of Antidepressant Non-Response in Late-Life DepressionCompletedNCT01931202Not applicableResults posted
• Predictors of Treatment Outcome With Cognitive Behavioral Therapy for DepressionCompletedNCT01922219Not applicableResults posted
• Placebo Effects in the Treatment of Depression: Cognitive and Neural MechanismsCompletedNCT01919216Phase 4Results posted
• Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive ImpairmentCompletedNCT01876823Phase 2/3Results posted
• Open Trial of Duloxetine in Outpatients With Irritable Bowel Syndrome Symptoms and Co-Morbid Major DepressionCompletedNCT01754493Phase 4Results posted
• Ketamine in the Treatment of Suicidal DepressionCompletedNCT01700829Phase 4Results posted
• Wake Therapy in the Treatment of DepressionCompletedNCT01431573Not applicableResults posted
• PET Biomarkers in Treatment Resistant DepressionTerminatedNCT01031810Phase 4Results posted
• Incorporating Patient Treatment Choice to Improve Treatment Retention in Depressed HispanicsCompletedNCT00742573Phase 2Results posted
• Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Panic Disorder With Comorbid Major DepressionCompletedNCT00521352Phase 2Results posted
• Does Dual Therapy Hasten Antidepressant Response?CompletedNCT00519428Phase 4Results posted
• Open-label Ziprasidone Study for Psychosis Treatment in AdolescentsCompletedNCT00421954Phase 3Results posted
• Dichotic Listening as a Predictor of Medication Response in DepressionCompletedNCT00404755Phase 4Results posted
• STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol AbuseCompletedNCT00369746Results posted
• Dichotic Listening as a Predictor of Medication Response in DepressionCompletedNCT00296725Phase 1/2Results posted
• Anti-suicidal Effects of Buprenorphine In Depressed IndividualsWithdrawnNCT05427981Phase 3
• Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast CancerSuspendedNCT04973930Phase 3
• Mechanisms of Emotion Regulation Underlying Successful CBT in DepressionCompletedNCT04328103
• A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older AdultsWithdrawnNCT01942187Phase 4
• A Stepped Care Model of Adolescent Depression Treatment in Primary CareCompletedNCT01443715Phase 2/3
• The Efficacy of Parent Involvement in the Treatment of Adolescent DepressionCompletedNCT00883519Phase 1/2
• Interpersonal Psychotherapy for Depressed Adolescents and ParentsCompletedNCT00619411Phase 1
• Prozac Treatment of Major Depression: Discontinuation StudyCompletedNCT00427128Phase 4
• Treatment of Depression Following Multiple Brain TestsCompletedNCT00296777Phase 4
• Are Two Antidepressants a Good Initial Treatment for Depression?CompletedNCT00296712Phase 4
• Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory DepressionTerminatedNCT00296686Phase 4
• Effectiveness of Culturally Based Congruent Care in Treating Hispanics With Major Depressive DisorderCompletedNCT00247195Not applicable