New York State Psychiatric Institute: Depressive Disorder trials

The registry lists 75 Depressive Disorder studies with New York State Psychiatric Institute as lead sponsor. 0 are open to participants now and 46 have results posted.

Phase 1 5Phase 2 10Phase 3 6Phase 4 37No phase 23(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Antidepressant Response in Older Adults With Comorbid PTSD and MDDTerminatedNCT04697693Phase 4Results posted
• Levodopa and Exercise for Older Adults With Depression and Psychomotor SlowingTerminatedNCT04650217Phase 4Results posted
• A Trial of "Opening Doors to Recovery" for Persons With Serious Mental IllnessesCompletedNCT04612777Not applicableResults posted
• 1/2-Dopaminergic Dysfunction in Late-Life Depression (The D3 Study)TerminatedNCT04493320Phase 4Results posted
• Ketamine Treatment Effects on Synaptic Plasticity in DepressionCompletedNCT04091971Phase 4Results posted
• Contact: Developing New Clinical Management StrategiesCompletedNCT03812588Phase 4Results posted
• L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older AdultsTerminatedNCT03761030Phase 4Results posted
• Treating Hearing Loss to Improve Mood and Cognition in Older AdultsCompletedNCT03321006Phase 4Results posted
• Neuroimaging in Patients Undergoing TMS for DepressionCompletedNCT02974296Not applicableResults posted
• Flavanol Augmentation for Antidepressant Non-Responsive Late Life DepressionTerminatedNCT02943096Not applicableResults posted
• A Study of L-DOPA for Depression and Slowing in Older AdultsCompletedNCT02744391Phase 4Results posted
• Biosignatures of Latuda for Bipolar DepressionCompletedNCT02239094Not applicableResults posted
• Developing New Clinical Management StrategiesCompletedNCT02082392Phase 4Results posted
• Imaging Dopamine Release in DepressionCompletedNCT02033369Phase 4Results posted
• Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older AdultsCompletedNCT01973283Phase 4Results posted
• Mechanisms of Antidepressant Non-Response in Late-Life DepressionCompletedNCT01931202Not applicableResults posted
• Predictors of Treatment Outcome With Cognitive Behavioral Therapy for DepressionCompletedNCT01922219Not applicableResults posted
• Placebo Effects in the Treatment of Depression: Cognitive and Neural MechanismsCompletedNCT01919216Phase 4Results posted
• Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive ImpairmentCompletedNCT01876823Phase 2/3Results posted
• Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older AdultsCompletedNCT01869374Phase 1/2Results posted
• Behavioral Activation (BA) for Medication-responsive Chronically Depressed Patients With Impaired Social FunctioningCompletedNCT01783080Not applicableResults posted
• Open Trial of Duloxetine in Outpatients With Irritable Bowel Syndrome Symptoms and Co-Morbid Major DepressionCompletedNCT01754493Phase 4Results posted
• Paroxetine/Bupropion in Depression With Suicide Attempt or Thoughts: fMRI StudyCompletedNCT01748955Phase 4Results posted
• Ketamine in the Treatment of Suicidal DepressionCompletedNCT01700829Phase 4Results posted
• Combination Treatment Study for Memory Impairment and DepressionCompletedNCT01658228Phase 4Results posted
• Desvenlafaxine vs. Placebo Treatment of Chronic DepressionCompletedNCT01537068Phase 4Results posted
• Wake Therapy in the Treatment of DepressionCompletedNCT01431573Not applicableResults posted
• Tranylcypromine Treatment of Bipolar DepressionCompletedNCT01430455Phase 4Results posted
• Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum DepressionCompletedNCT01379781Not applicableResults posted
• PET Biomarkers in Treatment Resistant DepressionTerminatedNCT01031810Phase 4Results posted
• Incorporating Patient Treatment Choice to Improve Treatment Retention in Depressed HispanicsCompletedNCT00742573Phase 2Results posted
• Effects of Adding Motivational Interviewing to Antidepressant Treatment for Hispanic Adults With DepressionCompletedNCT00564278Not applicableResults posted
• A Pilot Study Assessing EmSam in Bipolar DepressionTerminatedNCT00535262Phase 4Results posted
• Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Panic Disorder With Comorbid Major DepressionCompletedNCT00521352Phase 2Results posted
• Does Dual Therapy Hasten Antidepressant Response?CompletedNCT00519428Phase 4Results posted
• Treating Depression With Transcranial Direct Current Stimulation (tDCS)CompletedNCT00481988Phase 1/2Results posted
• Fluoxetine and Bupropion to Treat Patients With Depression and AlcoholismTerminatedNCT00449007Phase 4Results posted
• Paroxetine/Bupropion in Suicide Attempters/Ideators With Major DepressionTerminatedNCT00429169Phase 4Results posted
• Open-label Ziprasidone Study for Psychosis Treatment in AdolescentsCompletedNCT00421954Phase 3Results posted
• Dichotic Listening as a Predictor of Medication Response in DepressionCompletedNCT00404755Phase 4Results posted
• STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol AbuseCompletedNCT00369746Results posted
• Duloxetine for Chronic Depression: a Double-blind StudyCompletedNCT00360724Phase 4Results posted
• Dichotic Listening as a Predictor of Medication Response in DepressionCompletedNCT00296725Phase 1/2Results posted
• Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From DepressionCompletedNCT00249444Phase 2Results posted
• Free Venlafaxine Treatment for Marijuana Addiction and Depression - 1CompletedNCT00131456Phase 2Results posted
• Antidepressant Treatment of Melancholia in Late LifeCompletedNCT00000378Phase 4Results posted
• RCT of a Brief Video Intervention Targeting Peer Inclusion to Reduce Depression-related Stigma in AdolescentsCompletedNCT06360107Not applicable
• Reducing Depression Self-stigma and Increasing Treatment Seeking Intentions Among YouthCompletedNCT06172075Not applicable
• Anti-suicidal Effects of Buprenorphine In Depressed IndividualsWithdrawnNCT05427981Phase 3
• Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast CancerSuspendedNCT04973930Phase 3
• IM Ketamine vs Midazolam for Suicidal ER PatientsSuspendedNCT04640636Phase 4
• Mechanisms of Emotion Regulation Underlying Successful CBT in DepressionCompletedNCT04328103
• Add-on to Cognitive, Event-Related Potentials (ERP) and Electroencephalogram (EEG) Asymmetry in Affective DisordersWithdrawnNCT03278938Phase 4
• Out-patient Wake Therapy, Light Therapy and Sleep Phase Advance for DepressionCompletedNCT02750631Not applicable
• The Efficacy of a Depression Intervention for Adolescents With Depression and Sleep DisturbancesCompletedNCT02429674Not applicable
• A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older AdultsWithdrawnNCT01942187Phase 4
• A Pilot Trial of Interpersonal Psychotherapy for the Treatment of Depression in Patients With Prostate, Colorectal, Lung and Pancreatic CancerTerminatedNCT01940237Not applicable
• Cognitive Behavior Therapy for DepressionCompletedNCT01868711Not applicable
• A Clinical Trial of IPT-A to Prevent Suicide in Depressed Adolescents With Suicidal BehaviorCompletedNCT01447602Phase 3
• A Stepped Care Model of Adolescent Depression Treatment in Primary CareCompletedNCT01443715Phase 2/3
• Interpersonal Therapy for Depression in Breast CancerCompletedNCT01191580Phase 4
• The Efficacy of Parent Involvement in the Treatment of Adolescent DepressionCompletedNCT00883519Phase 1/2
• Effectiveness of Group Interpersonal Psychotherapy in Treating Women With Prenatal DepressionCompletedNCT00633178Not applicable
• Interpersonal Psychotherapy for Depressed Adolescents and ParentsCompletedNCT00619411Phase 1
• Comparing the Effects of Four Types of Electroconvulsive Therapy on Mood and Thinking in People With DepressionCompletedNCT00487500Phase 4
• Prozac Treatment of Major Depression: Discontinuation StudyCompletedNCT00427128Phase 4
• Treatment of Depression Following Multiple Brain TestsCompletedNCT00296777Phase 4
• Are Two Antidepressants a Good Initial Treatment for Depression?CompletedNCT00296712Phase 4
• A Pilot Study Assessing Duloxetine's Efficacy in Atypical DepressionCompletedNCT00296699Phase 4
• Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory DepressionTerminatedNCT00296686Phase 4
• Effectiveness of Culturally Based Congruent Care in Treating Hispanics With Major Depressive DisorderCompletedNCT00247195Not applicable
• Improving Retention of Hispanics Receiving Antidepressant TherapyCompletedNCT00057642Not applicable
• Optimizing Electroconvulsive Therapy for DepressionCompletedNCT00045916Phase 4
• Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD)CompletedNCT00006517Not applicable
• Clinical Trials of Two Non-drug Treatments for Chronic DepressionCompletedNCT00006172Not applicable