National Institutes of Health: Uterine Cervical Neoplasms trials

The registry lists 58 Uterine Cervical Neoplasms studies with National Institutes of Health as lead sponsor. 2 are open to participants now and 27 have results posted.

Early Phase 1 1Phase 1 18Phase 2 28Phase 3 3No phase 13(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)RecruitingNCT07281430Not applicable
• Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology StudiesEnrolling by invitationNCT04266093
• E7 TCR T Cell Induction Immunotherapy for Stage IIB-IVA Cervical CancerTerminatedNCT04476251Early Phase 1Results posted
• HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated CancersCompletedNCT04432597Phase 1/2Results posted
• Combination Immunotherapy in Subjects With Advanced HPV Associated MalignanciesCompletedNCT04287868Phase 1/2Results posted
• Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical CancerCompletedNCT03738228Phase 1Results posted
• Testing AZD1775 inC Combination With Radiotherapy and Chemotherapy in Cervical, Upper Vaginal and Uterine CancersTerminatedNCT03345784Phase 1Results posted
• Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical CancerCompletedNCT02921269Phase 2Results posted
• Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal CancerActive, not recruitingNCT02595879Phase 1Results posted
• Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell CancersCompletedNCT02487095Phase 1/2Results posted
• Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal CancersActive, not recruitingNCT02466971Phase 3Results posted
• Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical CancerActive, not recruitingNCT02257528Phase 2Results posted
• Ipilimumab in Treating Patients With Metastatic or Recurrent Human Papilloma Virus-Related Cervical CancerCompletedNCT01693783Phase 2Results posted
• Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Human Papillomavirus-Associated CancersCompletedNCT01585428Phase 2Results posted
• Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical CancerCompletedNCT01266447Phase 2Results posted
• Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By SurgeryCompletedNCT01026792Phase 2Results posted
• Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal CancerCompletedNCT00941070Phase 2Results posted
• Ixabepilone to Treat Cervical CancerTerminatedNCT00924066Phase 2Results posted
• A Study of Patients Receiving High-Dose Rate BrachytherapyCompletedNCT00924027Phase 2Results posted
• Paclitaxel and Cisplatin or Topotecan With or Without Bevacizumab in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical CancerCompletedNCT00803062Phase 3Results posted
• FDG and FMISO PET Hypoxia Evaluation in Cervical CancerCompletedNCT00559377Phase 2Results posted
• Fludeoxyglucose (FDG) F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial CancerCompletedNCT00416455Phase 1/2Results posted
• Sunitinib Malate in Treating Patients With Uterine Cervical Cancer That is Stage IVB, Recurrent, or Cannot Be Removed By SurgeryCompletedNCT00389974Phase 2Results posted
• Bevacizumab, Radiation Therapy, and Cisplatin in Treating Patients With Previously Untreated Locally Advanced Cervical CancerCompletedNCT00369122Phase 2Results posted
• Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial NeoplasiaCompletedNCT00303823Phase 2Results posted
• Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical CancerTerminatedNCT00262821Phase 3Results posted
• Tariquidar and Docetaxel to Treat Patients With Lung, Ovarian, Renal and Cervical CancerCompletedNCT00069160Phase 2Results posted
• Oxaliplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Cervical CancerCompletedNCT00057863Phase 2Results posted
• Bevacizumab in Treating Patients With Persistent or Recurrent Cancer of the CervixCompletedNCT00025233Phase 2Results posted
• Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S02)Active, not recruitingNCT06611553Not applicable
• Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S03)Active, not recruitingNCT06611540Not applicable
• Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S01)Active, not recruitingNCT06498661Not applicable
• A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon CancersCompletedNCT04708470Phase 1/2
• Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial CancerActive, not recruitingNCT04491942Phase 1
• Cervix Image Sharing Protocol (CISP)CompletedNCT03179306
• Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)Active, not recruitingNCT02465060Phase 2
• Improving Cervical Cancer Screening Among HIV-Infected Women in IndiaCompletedNCT02247999
• Chemoradiation Therapy and Ipilimumab in Treating Patients With Stages IB2-IIB or IIIB-IVA Cervical CancerCompletedNCT01711515Phase 1
• Paclitaxel, Cisplatin, and Veliparib in Treating Patients With Advanced, Persistent, or Recurrent Cervical CancerCompletedNCT01281852Phase 1
• Low-Cost Molecular Cervical Cancer Screening StudyCompletedNCT01231945
• A Comparison Study of Two Community Outreach-Based Approaches to Increase Participation of Women Living in the Mississippi Delta in Cervical Cancer ScreeningCompletedNCT01058148
• Extended Follow Up of Young Women in Costa Rica Who Received Vaccine for Human Papillomavirus Types 16 and 18 and Unvaccinated ControlsActive, not recruitingNCT00867464
• Human Papillomavirus Epidemiology in NigeriaCompletedNCT00804466Not applicable
• Human Papillomavirus (HPV) Testing to Improve Cervical Cancer Screening in the Mississippi DeltaCompletedNCT00443313
• Cervical Cancer Early Endpoints and DeterminantsCompletedNCT00339989
• Phase I Study of Intravenous Triapine (IND # 68338) in Combination With Pelvic Radiation Therapy With or Without Weekly Intravenous Cisplatin Chemotherapy for Locally Advanced Cervical, Vaginal, or Pelvic Gynecologic MalignanciesCompletedNCT00335998Phase 1
• Radiation Therapy in Treating Patients With Cervical CancerCompletedNCT00278304Phase 2
• EF5 in Finding Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Cervical, Endometrial, or Ovarian Epithelial CancerCompletedNCT00107445Phase 2
• Healing Touch and Relaxation Therapies in Cervical Cancer PatientsCompletedNCT00084123Phase 2
• Immunotoxin Therapy in Treating Patients With Advanced Solid TumorsCompletedNCT00066651Phase 1
• Vaccine Therapy in Preventing Cervical Cancer in Patients With Cervical Intraepithelial NeoplasiaCompletedNCT00054041Phase 2
• Gefitinib in Treating Patients With Cervical CancerCompletedNCT00049556Phase 2
• 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)CompletedNCT00031681Phase 1
• Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney DysfunctionCompletedNCT00030498Phase 1
• Vaccine Therapy in Treating Patients With Advanced or Recurrent CancerCompletedNCT00019110Phase 1
• Vaccine Therapy and Biological Therapy in Treating Patients With Advanced CancerCompletedNCT00019084Phase 2
• Immunotoxin Therapy in Treating Patients With Advanced CancerCompletedNCT00006981Phase 1
• Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/NeuCompletedNCT00004074Phase 1