National Institutes of Health: Thrombocytopenia trials

The registry lists 21 Thrombocytopenia studies with National Institutes of Health as lead sponsor. 2 are open to participants now and 10 have results posted.

Phase 1 7Phase 2 12Phase 4 1No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)RecruitingNCT04304820Phase 2Results posted
• Screening for Hematology Branch ProtocolsEnrolling by invitationNCT00001620
• The SOLID Platelet StudyTerminatedNCT03712618Phase 2Results posted
• Complement Inhibition Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Patients With Severe ThrombocytopeniaCompletedNCT02298933Phase 2Results posted
• Eltrombopag With Standard Immunosuppression for Severe Aplastic AnemiaActive, not recruitingNCT01623167Phase 1/2Results posted
• Eltrombopag for Moderate Aplastic AnemiaCompletedNCT01328587Phase 2Results posted
• A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)CompletedNCT00961064Phase 2Results posted
• A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia PatientsCompletedNCT00922883Phase 2Results posted
• Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and HormonesTerminatedNCT00556400Phase 1/2Results posted
• Three Immunosuppressive Treatment Regimens for Severe Aplastic AnemiaCompletedNCT00260689Phase 2Results posted
• Anti-D for Treating Thrombocytopenia in Adults Infected With Hepatitis C Virus With or Without HIV Co-InfectionTerminatedNCT00239733Phase 4Results posted
• Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-Lymphocyte Antigen 4 (CTLA4) HaploinsufficiencyWithdrawnNCT03733067Phase 1/2
• Complement (C1q) Binding to HLA Antibodies in a Solid-phase Immunoassay and Clinical Effect on Platelet TransfusionCompletedNCT02858323
• Lenalidomide and Alvocidib in Treating Patients With Relapsed or Refractory B-cell Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaCompletedNCT00735930Phase 1
• Daclizumab to Treat Chronic Immune ThrombocytopeniaCompletedNCT00049725Phase 2
• Identification of Donors of CD36-Deficient Platelets Among Japanese Individuals on the NIH CampusCompletedNCT00015639
• Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid CancerCompletedNCT00012376Phase 1
• Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure SyndromesCompletedNCT00004787Phase 2
• Stem Cell Transplantation (SCT) for Genetic DiseasesCompletedNCT00004378Not applicable
• Treatment of Autoimmune Thrombocytopenia (AITP)CompletedNCT00001630Phase 1
• Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With CyclosporineCompletedNCT00001533Phase 1