National Institutes of Health: Metabolic Diseases trials

The registry lists 28 Metabolic Diseases studies with National Institutes of Health as lead sponsor. 11 are open to participants now and 5 have results posted.

Phase 1 3Phase 2 5No phase 23(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and AdultsNot yet recruitingNCT07388537
• A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism DisordersRecruitingNCT06092346
• Characterization of Dysmorphology in Subjects With Creatine Transporter DeficiencyRecruitingNCT05600946
• A Natural History Study of Metabolic Sizing in Health and DiseaseRecruitingNCT05398783
• Natural History of the Human Biological Response to Environmental Exposure and InjuryRecruitingNCT04888923
• Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaRecruitingNCT02890342
• Evaluation of Children With Endocrine and Metabolic-Related ConditionsRecruitingNCT02769975
• Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular SystemRecruitingNCT01143454
• Use of Cysteamine in the Treatment of CystinosisRecruitingNCT00359684
• Clinical and Laboratory Study of Methylmalonic AcidemiaRecruitingNCT00078078
• Clinical and Basic Investigations Into Hermansky-Pudlak SyndromeRecruitingNCT00001456
• Effects of Colchicine in Non-Diabetic Adults With Metabolic SyndromeCompletedNCT02153983Phase 1/2Results posted
• Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase DeficiencyCompletedNCT02019667Phase 2Results posted
• Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak SyndromeTerminatedNCT00467831Phase 1/2Results posted
• Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs)CompletedNCT00119405Results posted
• Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected AdultsCompletedNCT00119379Phase 2Results posted
• Chile Biliary Longitudinal StudyCompletedNCT02692911
• The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI)CompletedNCT01778569
• Bisphosphonate Users Radiographic Characteristics of the Hip (BURCH) StudyCompletedNCT01360099
• The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic DiseaseCompletedNCT01143493
• Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoietic Stem Cell Transplant RecipientsTerminatedNCT00504218
• Chromium Picolinate for the Treatment of Metabolic SyndromeCompletedNCT00128154Not applicable
• Electromagnetic Treatment For Bone Loss After Forearm FractureCompletedNCT00067834Phase 1/2
• Studies of Children With Metabolic and Other Genetic DisordersCompletedNCT00025870
• Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in DepressionCompletedNCT00001916
• Study of Glycogen Storage Disease and Associated DisordersCompletedNCT00001342
• Genetic and Family Studies of Inherited Muscle DiseasesCompletedNCT00001331
• Metabolic Abnormalities in Children With EpilepsyCompletedNCT00001325