National Institutes of Health: Liver Diseases trials

The registry lists 45 Liver Diseases studies with National Institutes of Health as lead sponsor. 4 are open to participants now and 10 have results posted.

Phase 1 7Phase 2 9Phase 3 6Phase 4 1No phase 24(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell TransplantNot yet recruitingNCT05722210
• Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research ApproachRecruitingNCT04685200
• Natural History of Noncirrhotic Portal HypertensionRecruitingNCT02417740
• Evaluation of Patients With Liver DiseaseRecruitingNCT00001971
• Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)CompletedNCT04216589Phase 2Results posted
• Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda InterferonCompletedNCT03600714Phase 2Results posted
• Losartan for the Treatment of Pediatric NAFLDTerminatedNCT03467217Phase 2Results posted
• Cysteamine Bitartrate Delayed-Release for the Treatment of NAFLD in ChildrenCompletedNCT01529268Phase 2/3Results posted
• The Farnesoid X Receptor (FXR) Ligand Obeticholic Acid in NASH Treatment Trial(FLINT)CompletedNCT01265498Phase 2Results posted
• Pioglitazone to Treat Fatty Liver in Patients With HIV and Hepatitis C InfectionsTerminatedNCT00742326Phase 4Results posted
• Immune System Suppression With Alemtuzumab and Tacrolimus in Liver Transplantation PatientsCompletedNCT00105235Phase 2Results posted
• Pegylated Interferon Alfa-2a Maintenance Therapy and Liver Disease Progression in People Infected With Both HIV and Hepatitis C Virus (HCV)CompletedNCT00078403Phase 2Results posted
• Treatment of Nonalcoholic Fatty Liver Disease in Children (TONIC)CompletedNCT00063635Phase 3Results posted
• Pioglitazone vs Vitamin E vs Placebo for Treatment of Non-Diabetic Patients With Nonalcoholic Steatohepatitis (PIVENS)CompletedNCT00063622Phase 3Results posted
• Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Liver DiseaseCompletedNCT05669677
• TReatment for ImmUne Mediated PathopHysiologyActive, not recruitingNCT04862221Phase 2
• Longitudinal Assessment of Transient Elastography in Cystic FibrosisCompletedNCT03001388
• MRI to Characterize and Predict CF Liver Disease in PUSH CohortCompletedNCT02979340
• Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver DiseaseCompletedNCT02520609
• Palmitate Breath Test to Assess Fatty Acid Oxidation in Non Alcoholic Fatty Liver Disease (NAFLD)CompletedNCT02363309
• Comparing Pain in Patients Undergoing Percutaneous Versus Transjugular Techniques of Liver BiopsyCompletedNCT02311348
• Evaluation of Sickle Cell Liver DiseaseCompletedNCT01950429
• The Physiology of Fatigue in Patients With Chronic Liver DiseaseCompletedNCT01867385
• Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver DysfunctionCompletedNCT01638533Phase 1
• Genetic Studies of Non-Alcoholic Fatty Liver DiseaseTerminatedNCT01629095
• HIV Accelerated Liver Disease in UgandaCompletedNCT01524562
• Long-Term Study of Liver Disease in People With Hepatitis B and/or Hepatitis C With or Without HIV InfectionCompletedNCT01350648
• Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant SurvivalCompletedNCT00531921
• Phase I Trial of Silymarin for Chronic Liver DiseasesCompletedNCT00389376Phase 1
• Liver Fibrosis in HIV-Infected Patients With Elevated Liver Enzymes on Antiretroviral TherapyCompletedNCT00326482
• Bortezomib in Treating Patients With Advanced Cancer and Liver DysfunctionCompletedNCT00091117Phase 1
• The Effect of Good Bacteria on Nonalcoholic Fatty Liver Disease in DiabeticsTerminatedNCT00068094Phase 1/2
• Detection and Cytotoxic T Lymphocyte Therapy of Post-Transplant Lymphoproliferative Disorder After Liver TransplantCompletedNCT00063648Phase 1
• Gabapentin to Treat Itch in Patients With Liver DiseaseCompletedNCT00058890Phase 3
• Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver DysfunctionCompletedNCT00025415Phase 1
• Mechanisms of Inflammatory Liver InjuryCompletedNCT00011284
• Oxaliplatin to Treat Advanced Cancers With Liver DysfunctionCompletedNCT00006062Phase 1
• Vancomycin Resistant Enterococci in Patients Awaiting Liver Transplantation at the University of Michigan: Prevalence, Risk Factors, Natural History and Outcome of ColonizationStatus unknownNCT00005667
• Genetics of Hepatitis C Virus InfectionCompletedNCT00005657
• Natural History of Post-transfusion Non-A, Non-B HepatitisCompletedNCT00005306
• Magnetic Resonance Imaging of Blood Flow in the Liver and AbdomenCompletedNCT00001719
• Diagnosis and Treatment of Patients With Cystic FibrosisTerminatedNCT00001223
• A Study of Zidovudine in HIV-Infected Patients With Liver DiseaseCompletedNCT00001001Not applicable
• Hepatitis B Vaccine Clinical TrialCompletedNCT00000583Phase 3
• Interruption of Maternal-to-Infant Transmission of Hepatitis B by Means of Hepatitis B Immune GlobulinCompletedNCT00000580Phase 3