National Institutes of Health: Liver Cirrhosis trials

The registry lists 22 Liver Cirrhosis studies with National Institutes of Health as lead sponsor. 1 are open to participants now and 3 have results posted.

Phase 1 5Phase 2 7Phase 3 7No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United StatesRecruitingNCT05832229Phase 2
• Erlotinib Hydrochloride in Preventing Liver Cancer in Patients With Cirrhosis of the LiverCompletedNCT02273362Phase 1/2Results posted
• New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis CCompletedNCT01888900Phase 2Results posted
• Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard TreatmentCompletedNCT00006164Phase 3Results posted
• Low-Dose Danazol for the Treatment of Telomere Related DiseasesCompletedNCT03312400Phase 2
• Defined Green Tea Catechin Extract in Preventing Liver Cancer in Participants With CirrhosisActive, not recruitingNCT03278925Phase 1
• Genetic Studies of Non-Alcoholic Fatty Liver DiseaseTerminatedNCT01629095
• Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic FibrosisCompletedNCT01144507
• A Study of Molecular and Genetic Factors for Liver Cancer in the Greater Baltimore AreaCompletedNCT00913757
• Liver Fibrosis in HIV-Infected Patients With Elevated Liver Enzymes on Antiretroviral TherapyCompletedNCT00326482
• SAMe to Treat Biliary Cirrhosis SymptomsTerminatedNCT00125281Phase 2
• Treatment of Cholestatic Pruritus With SertralineCompletedNCT00058903Phase 2
• Prevention of Esophageal Varices by Beta-Adrenergic BlockersCompletedNCT00006398Phase 3
• Ursodiol-Methotrexate for Primary Biliary CirrhosisCompletedNCT00006168Phase 3
• North American Study for the Treatment of Refractory Ascites (NASTRA)CompletedNCT00006166Phase 3
• Decompression Intervention of Variceal Rebleeding Trial (DIVERT)CompletedNCT00006161Phase 3
• Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and EndotoxemiaStatus unknownNCT00005107Phase 1
• Pilot Study of Budesonide for Patients With Primary Sclerosing CholangitisCompletedNCT00004842Phase 1
• Phase II Study of Lactulose and Circadian Rhythms in Patients With CirrhosisCompletedNCT00004796Phase 2
• Phase III Randomized Study of Ursodiol With Vs Without Methotrexate for Primary Biliary CirrhosisCompletedNCT00004784Phase 3
• Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary CirrhosisCompletedNCT00004748Phase 3
• Phase I Study of Colchicine Therapy in Childhood Hepatic CirrhosisStatus unknownNCT00004368Phase 1