National Institutes of Health: Kidney Diseases trials

The registry lists 62 Kidney Diseases studies with National Institutes of Health as lead sponsor. 3 are open to participants now and 7 have results posted.

Early Phase 1 1Phase 1 11Phase 2 13Phase 3 12Phase 4 1No phase 30(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Podocyte DiseasesRecruitingNCT06664814Phase 2
• Rituximab Plus Cyclosporine in Idiopathic Membranous NephropathyRecruitingNCT00977977Phase 2
• Immune System Related Kidney DiseaseRecruitingNCT00001979
• Impact of CCR5 Blockade in HIV+ Kidney Transplant RecipientsCompletedNCT02741323Phase 2Results posted
• HALT Progression of Polycystic Kidney Disease Study BCompletedNCT01885559Phase 3Results posted
• Renoprotection in Early Diabetic Nephropathy in Pima IndiansCompletedNCT00340678Phase 3Results posted
• HALT Progression of Polycystic Kidney Disease Study ACompletedNCT00283686Phase 3Results posted
• Steroid-Free Versus Steroid-Based Immunosuppression in Pediatric Renal (Kidney) TransplantationCompletedNCT00141037Phase 1/2Results posted
• Cidofovir in Renal Transplant Recipients With BKVNTerminatedNCT00138424Phase 1/2Results posted
• Effectiveness of the Investigational Drug Campath-1H in Preventing Rejection of Transplanted KidneysCompletedNCT00001984Phase 2Results posted
• African American Study of Kidney Disease and HypertensionCompletedNCT04364139Phase 3
• The Modification of Diet in Renal Disease StudyCompletedNCT04364113Phase 3
• Gut Microbiome and p-Inulin in CKD - TarGut CKD StudyStatus unknownNCT03348592Not applicable
• Empaglifozin in Early Diabetic Kidney DiseaseWithdrawnNCT03173963Phase 3
• A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte DiseasesCompletedNCT02639260Phase 1
• A Retrospective Multicenter Study to Determine 5-Year Clinical Outcomes in Subjects Previously Enrolled in the CTOT-01 StudyCompletedNCT01974999
• Role of Donor Genetics and Recipient Genetics in Kidney Transplant OutcomesCompletedNCT01143532
• Live Kidney Donor Study - Cross-Sectional and Historical Cohort StudyCompletedNCT00951977
• Immune Development in Pediatric Transplantation (IMPACT)CompletedNCT00951353
• Cancer Risk in Organ Transplant Recipients and End-Stage Renal DiseaseCompletedNCT00904579
• Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal DiseaseStatus unknownNCT00852787Phase 4
• Cognitive Behavioral Treatment of Depression in ESRD Patients on DialysisCompletedNCT00618475Not applicable
• African American Study of Kidney Disease and Hypertension ABPM Pilot StudyCompletedNCT00582777Phase 2/3
• Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage DisequilibriumCompletedNCT00559767
• Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant SurvivalCompletedNCT00531921
• Effects of N-acetylcysteine on Muscle Fatigue in HemodialysisCompletedNCT00440869Phase 1
• Oxidative Stress and Hemodialysis Access FailureCompletedNCT00410449
• Improving Outcomes in Patients With Kidney Disease Due to DiabetesCompletedNCT00381134Phase 2
• Delaying the Progression of Diabetic Nephropathy in Pima IndiansCompletedNCT00353600
• Genetic Susceptibility to Cardiovascular Disease in Patients on Kidney DialysisCompletedNCT00340119
• Prospective Studies of the Natural History of Diabetes Mellitus and Its Complications in the Gila River Indian CommunityCompletedNCT00339482
• Urine Testing to Detect Kidney Transplant RejectionCompletedNCT00337220
• Noninvasive Methods to Monitor Graft Survival in Kidney Transplant PatientsCompletedNCT00308802
• The Family Investigation of Nephropathy and Diabetes StudyCompletedNCT00301249
• Frequent Hemodialysis Network: Nocturnal TrialStatus unknownNCT00271999Phase 2/3
• Hydroxyurea and Erythropoietin to Treat Sickle Cell AnemiaCompletedNCT00270478Phase 1
• Frequent Hemodialysis Network: Daily TrialCompletedNCT00264758Phase 2/3
• Kidney Disease BiomarkersCompletedNCT00255398
• Optimal Treatment for Kidney Disease in HIV Infected AdultsWithdrawnNCT00089518Phase 3
• Soy Protein in Early Diabetic NephropathyCompletedNCT00067678Phase 1/2
• Treatment of Diabetic NephropathyTerminatedNCT00065559Not applicable
• Reducing the Risk of Transplant Rejection: Simultaneous Kidney and Bone Marrow TransplantCompletedNCT00063817Phase 1
• Omega-3 Fatty Acids That Affect the Immune System in Kidney Transplant PatientsCompletedNCT00047983Early Phase 1
• Blood Component Collection From Patients With Rheumatic or Kidney Disease and Healthy VolunteersTerminatedNCT00031174
• MRI to Detect Embolism Following Angiography and Angioplasty-Stenting of the Renal ArteryCompletedNCT00027469Phase 1
• Evaluation of New Test Method to Measure Kidney FunctionCompletedNCT00026715
• Search for New Methods to Detect Acute Renal FailureTerminatedNCT00026702
• Antibody and Delayed Cyclosporine Versus Initial Cyclosporine Alone in Patients Receiving Kidney TransplantsCompletedNCT00007787Not applicable
• Angiotensin-Converting Enzyme Gene Polymorphism and the Risk of Chronic Allograft NephropathyCompletedNCT00006328
• Dynamic Aspects of Amino Acid MetabolismStatus unknownNCT00005767
• Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance DialysisCompletedNCT00004340Phase 2
• Effect of Dialysis Dose and Membrane Flux in Maintenance HemodialysisCompletedNCT00004285Not applicable
• Drugs for High Blood Pressure and High Cholesterol in American Indians With Type 2 DiabetesCompletedNCT00004266Phase 3
• Determination of Kidney FunctionTerminatedNCT00001978
• Monitoring for Tolerance to Kidney or Combined Kidney-Pancreas TransplantsCompletedNCT00001858
• Oxaliplatin in Cancer Patients With Impaired Kidney FunctionCompletedNCT00001835Phase 1
• Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac TumorsCompletedNCT00001668
• Genetic Markers for Focal Segmental GlomerulosclerosisCompletedNCT00001393
• A Trial of Carboxypeptidase-G2 (CPDG2) and Thymidine for the Management of Patients With Methotrexate Toxicity and Renal DysfunctionCompletedNCT00001298Phase 1
• An Evaluation of IV Gamma Globulin As a Method to Improve Kidney Transplant Survival in Patients With End-Stage Renal Disease Who Are Highly Sensitized to Transplant AntigensCompletedNCT00000935Phase 3
• A Phase II Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Efficacy of Prednisone Therapy in HIV-Associated Nephropathy (HIVAN)CompletedNCT00000819Phase 2
• A Study of Zidovudine in HIV-Infected Patients With Kidney ProblemsWithdrawnNCT00000685Phase 1