National Institutes of Health: Inflammatory Bowel Diseases trials

The registry lists 18 Inflammatory Bowel Diseases studies with National Institutes of Health as lead sponsor. 5 are open to participants now and 2 have results posted.

Phase 1 5Phase 2 3No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruitingNCT07619547
• Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research ApproachRecruitingNCT04685200
• Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVORecruitingNCT03816345Phase 1
• Clinical and Basic Investigations Into Hermansky-Pudlak SyndromeRecruitingNCT00001456
• Immune Regulation in Ulcerative Colitis or Crohn s DiseaseRecruitingNCT00001184
• NIH Substudy of AIN457 (Anti-IL-17 Monoclonal Antibody) for Treatment of Moderate to Severe Crohn's DiseaseTerminatedNCT00936585Not applicableResults posted
• Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous DiseaseTerminatedNCT00325078Phase 1/2Results posted
• The Role of Gut Microbiome in Predicting Comorbidities and Complications in Children With Inflammatory Bowel DiseaseWithdrawnNCT05652491
• Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory ComplicationsCompletedNCT05104723Phase 1/2
• Empagliflozin as a Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyCompletedNCT05078879Phase 1
• Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous DiseaseCompletedNCT03983837Phase 2
• Natural History of Intestinal Inflammation in People With Primary Immune DysregulationsWithdrawnNCT03278912
• Bone Marrow Stromal Cells for Inflammatory Bowel DiseasesTerminatedNCT01851343Phase 1
• Telomere Repair Gene Mutation in Inflammatory Bowel DiseaseCompletedNCT00353639
• Genetic Studies of Inflammatory Bowel DiseaseCompletedNCT00340444
• Infectious Agents in Pediatric Crohn'sCompletedNCT00237055
• Collection of Specimens for Study of Inflammatory Bowel DiseaseCompletedNCT00086554
• A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel DiseaseCompletedNCT00035074Not applicable