National Institutes of Health: Encephalitis trials

The registry lists 15 Encephalitis studies with National Institutes of Health as lead sponsor. 1 are open to participants now and 3 have results posted.

Phase 1 5Phase 2 3Phase 3 1No phase 7(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)RecruitingNCT01730131
• VRC 313: A Trivalent Virus-like Particle (VLP) Encephalitis Vaccine (WEVEE) in Healthy AdultsCompletedNCT03879603Phase 1Results posted
• Vaccine Study for Tick-Borne Encephalitis Virus (TBEV)TerminatedNCT01031537Phase 2Results posted
• Long Term Treatment of Herpes Simplex Encephalitis (HSE) With ValacyclovirCompletedNCT00031486Phase 3Results posted
• Procedural Motor Memory in Long COVID-19CompletedNCT05746624
• Evaluating the Safety and Immunogenicity of a Live Attenuated West Nile Virus Vaccine for West Nile Encephalitis in Adults 50 to 65 Years of AgeCompletedNCT02186626Phase 1
• Brain Inflammation in Major Depressive Disorder BackgroundCompletedNCT01851356
• Safety of and Immune Response to a Tick-Borne Encephalitis Vaccine (LGT(TP21)/DEN4) in Healthy AdultsCompletedNCT00118924Phase 1
• Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4-3'delta30) in Healthy AdultsCompletedNCT00094718Phase 1
• Natural History of West Nile Virus InfectionCompletedNCT00069303
• IVIG - West Nile Encephalitis: Safety and EfficacyCompletedNCT00068055Phase 1/2
• Structure of the Herpes Simplex Virus ReceptorCompletedNCT00001648
• Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic EncephalitisCompletedNCT00000794Phase 2
• A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDSCompletedNCT00000674Not applicable
• A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii InfectionCompletedNCT00000666Not applicable