National Institutes of Health: Diabetes Mellitus, Type 2 trials

The registry lists 77 Diabetes Mellitus, Type 2 studies with National Institutes of Health as lead sponsor. 1 are open to participants now and 7 have results posted.

Early Phase 1 2Phase 1 9Phase 2 11Phase 3 6Phase 4 4No phase 47(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort StudyRecruitingNCT06730113
• Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)CompletedNCT04209075Phase 2Results posted
• Title: Therapeutic Targets in African-American Youth With Type 2 DiabetesCompletedNCT02960659Phase 1/2Results posted
• Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and DiabetesCompletedNCT02107976Not applicableResults posted
• The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy VolunteersCompletedNCT00339833Phase 4Results posted
• Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)CompletedNCT00081328Phase 3Results posted
• Diabetes Prevention Program Outcomes StudyCompletedNCT00038727Phase 3Results posted
• Action to Control Cardiovascular Risk in Diabetes (ACCORD)CompletedNCT00000620Phase 3Results posted
• Empaglifozin in Early Diabetic Kidney DiseaseWithdrawnNCT03173963Phase 3
• TODAY2 Phase 2 Follow-upCompletedNCT02310724
• Mechanisms of Diabetic Kidney Disease in American IndiansCompletedNCT01878045
• Lifestyle Interventions for Expectant Mothers (LIFE-Moms Phoenix) - PhoenixCompletedNCT01812694Phase 3
• TODAY2 Phase 1 Immediate Post-Intervention Observational Follow-up StudyCompletedNCT01364350
• Type 2 Diabetes and Obesity in Mexican Pimas: Gene-Environment InteractionCompletedNCT01168297
• Molecular and Clinical Profile of Diabetes Mellitus and Its ComplicationsSuspendedNCT01105858
• Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes MellitusTerminatedNCT01083108Phase 2
• Quitting Caffeine for Better Glucose MetabolismCompletedNCT01030796Phase 1
• Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy StudyCompletedNCT01007266Phase 2
• Natural History of Autoimmune Diabetes and Its ComplicationsTerminatedNCT00896610
• Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese WomenCompletedNCT00862433Phase 1
• Community Health Workers in Diabetes Care in American SamoaCompletedNCT00850824Not applicable
• Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy IndividualsCompletedNCT00813228Phase 1
• A Trial of Two Diets for Weight and Diabetes ManagementCompletedNCT00729196Not applicable
• TODAY Genetics StudyCompletedNCT00722397
• Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in YouthCompletedNCT00693511Not applicable
• Antioxidant Treatment of Type 2 DiabetesCompletedNCT00609102Early Phase 1
• Computer Based Intervention for Type 2 Diabetes in YouthCompletedNCT00570466Not applicable
• The Effect of Ethanol on Overnight Glucose Regulation in Type 2CompletedNCT00566592Not applicable
• Changing Physical Activity Behavior in Individuals With Type 2 Diabetes Using Counceling and Information From Continuous Glucose MonitoringCompletedNCT00542698Phase 1
• Middle-School Based Primary Prevention Trial of Type 2 DiabetesCompletedNCT00458029Not applicable
• Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes MellitusCompletedNCT00445627
• Experimental Studies of the Effects of Caffeine on Glucose RegulationCompletedNCT00432887Early Phase 1
• Insulin Secretory Defects in Pima Indians at High Risk for NIDDMCompletedNCT00410800
• Family Investigation of Nephropathy and Diabetes (F.I.N.D.)Active, not recruitingNCT00342927
• Cross-Sectional and Longitudinal Studies of "Pre-Diabetes" in the Pima IndiansCompletedNCT00340132
• Prospective Studies of the Natural History of Diabetes Mellitus and Its Complications in the Gila River Indian CommunityCompletedNCT00339482
• The Diabetes TeleCare StudyCompletedNCT00288132Not applicable
• GIP: Glucose-dependent Insulinotropic PeptideCompletedNCT00239707Phase 1
• Exercise Training in Type 2 Diabetes and HypertensionCompletedNCT00212303Phase 4
• Insulin Resistance and Central Nervous System (CNS) Function in Type 2 DiabetesCompletedNCT00212290Phase 4
• Evaluation of Diabetes Self-Management Consultant CareCompletedNCT00109720Not applicable
• Improving Diabetes in Primary Care (IMPACT)CompletedNCT00108927
• Rosiglitazone to Reverse Metabolic Defects in DiabetesCompletedNCT00094796Phase 2
• Evaluating "Health at Every Size"(HAES) as an Alternative Obesity Treatment ModelCompletedNCT00074633Not applicable
• Insulin Resistance and Insulin SecretionWithdrawnNCT00073294Not applicable
• Prevention of Type 2 Diabetes Mellitus in ChildrenCompletedNCT00073268Phase 1
• Improving Medication Adherence in Comorbid ConditionsCompletedNCT00072891Not applicable
• Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 DiabetesCompletedNCT00065676Phase 2
• Pilot Study of Vedic Medicine for Type 2 DiabetesCompletedNCT00065650Phase 2
• Screening Adolescents for Type 2 Diabetes Mellitus in a Community ClinicStatus unknownNCT00042042Not applicable
• Mechanisms of Pro-Thrombosis in Diabetes Mellitus -- Ancillary to BARI 2DCompletedNCT00041405
• Epidemiology of Cardiovascular Disease in DiabetesCompletedNCT00037297
• VA HDL Intervention Trial (VA-HIT) Ancillary Study Data AnalysisCompletedNCT00035711
• Ginkgo Biloba Extract and the Insulin Resistance SyndromeCompletedNCT00032474Phase 1/2
• Sleep Apnea in Look AHEAD Participants - Ancillary to Look AHEADCompletedNCT00031239
• Heavy Metals, Obesity and Cardiovascular Risk - Ancillary to Look AHEADCompletedNCT00031213
• MRI Derived Organ & Tissue Mass Changes With Weight Loss - Ancillary to Look AHEADCompletedNCT00031200
• Prenatal Nutrition and Adult DiseaseCompletedNCT00024583
• Randomized Trial of Health Events Costs in Diabetic BlacksCompletedNCT00022750Not applicable
• Non-Traditional Cardiovascular Risk Factors in Type 2 Diabetes Mellitus - Ancillary to VA Study of Glycemic ControlCompletedNCT00021944
• Serum Total Homocysteine and C-Reactive Protein - Ancillary to IDNTCompletedNCT00021918
• NNC 90-1170 Mechanism of Action: A Double-Blind, Randomized, Single-Center, Placebo-Controlled, Crossover Study to Examine Beta-Cell Responsiveness to Graded Glucose Infusion in Subjects With Type 2 DiabetesCompletedNCT00013910Phase 1
• Effects of Reiki on Painful Neuropathy and Cardiovascular Risk FactorsCompletedNCT00010751Phase 2
• NEW DAY: Nutrition, Exercise, Weight Loss, Diabetes And YouCompletedNCT00007800Phase 2
• Acute Glycemic Effects of a Very Low Fat Diet in Type 2 DiabetesCompletedNCT00006432Not applicable
• Native Hawaiian Diabetes Intervention ProgramCompletedNCT00006165Not applicable
• Computer-assisted Diabetes Self-management InterventionsCompletedNCT00006163Phase 4
• Lifestyle Interventions to Reduce Diabetes RiskCompletedNCT00006162Not applicable
• Health Effects of Liposuction in Overweight Women With Elevated Insulin Levels, Impaired Glucose Tolerance and/or Type 2 DiabetesCompletedNCT00005760
• Multi-Ethnic Study of Atherosclerosis (MESA)Active, not recruitingNCT00005487
• Genetics of Atherosclerosis in Mexican AmericansCompletedNCT00005462
• Prospective Study of Diabetes-related Vascular Disease in Oklahoma IndiansCompletedNCT00005193
• Diabetes Prevention ProgramCompletedNCT00004992Phase 3
• Education and Group Support for Diabetic HispanicsCompletedNCT00004983Not applicable
• Identification and Therapy Efficacy of Type 2 Diabetes in Hispanic PatientsStatus unknownNCT00004572
• Study of the Effects of Vitamin C on Patients With Type 2 DiabetesCompletedNCT00001870Phase 2
• Methods for Measuring Insulin SensitivityCompletedNCT00001625