National Institutes of Health: Crohn Disease trials

The registry lists 17 Crohn Disease studies with National Institutes of Health as lead sponsor. 3 are open to participants now and 2 have results posted.

Phase 1 7Phase 2 5No phase 7(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruitingNCT07619547
• Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVORecruitingNCT03816345Phase 1
• An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With UstekinumabRecruitingNCT03167437Phase 1/2
• Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated DysplasiaTerminatedNCT01111292Phase 1/2Results posted
• NIH Substudy of AIN457 (Anti-IL-17 Monoclonal Antibody) for Treatment of Moderate to Severe Crohn's DiseaseTerminatedNCT00936585Not applicableResults posted
• The Role of Gut Microbiome in Predicting Comorbidities and Complications in Children With Inflammatory Bowel DiseaseWithdrawnNCT05652491
• Empagliflozin as a Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyCompletedNCT05078879Phase 1
• Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous DiseaseCompletedNCT03983837Phase 2
• T and B Cell Responses in Autoimmune DiseasesTerminatedNCT01947036
• Glucocorticoid-induced Osteopenia in ChildrenCompletedNCT00289328
• The Immunological and Blood Effects of STA-5326 Mesylate on Patients With Crohn's DiseaseCompletedNCT00250198Phase 2
• Infectious Agents in Pediatric Crohn'sCompletedNCT00237055
• Imuran Dosing in Crohn's Disease StudyTerminatedNCT00113503Phase 2
• Quality of Life in Pediatric Inflammatory Bowel DiseaseCompletedNCT00061737
• Extracorporeal Photopheresis to Maintain Symptoms Remission During Steroid Withdrawal in Patients With Steroid-Dependent Crohn's DiseaseCompletedNCT00056355Phase 1
• G-CSF to Treat Crohn's DiseaseCompletedNCT00025805Phase 1
• Monoclonal Antibody Treatment of Crohn's DiseaseCompletedNCT00007163Phase 1