National Institutes of Health: Alzheimer Disease trials
The registry lists 69 Alzheimer Disease studies with National Institutes of Health as lead sponsor. 3 are open to participants now and 4 have results posted.
Phase 1 6Phase 2 11Phase 3 11Phase 4 1No phase 41(a study in two phases counts in both)
Studies
Open to participants first, then studies with results posted, then the rest; newest registration first within each.
- Neuroplasticity Enhancement From Cognitive Training Reinforced by PsilocybinRecruitingNCT07721467Phase 2
- Amyloid PET Imaging in the Baltimore Longitudinal Study of AgingRecruitingNCT07099053
- PET Imaging of Cyclooxygenases in Neurodegenerative Brain DiseaseRecruitingNCT04396873Phase 1
- Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults 55 Years Old or OlderCompletedNCT04421014Not applicableResults posted
- Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain FunctionCompletedNCT02460783Not applicableResults posted
- A Pilot Clinical Trial of Exendin-4 in Alzheimer's DiseaseTerminatedNCT01255163Phase 2Results posted
- Ginkgo Biloba Prevention Trial in Older IndividualsCompletedNCT00010803Phase 3Results posted
- On Site Sensors Monitoring Impacts of Cognitive Decline on ADLsStatus unknownNCT04871698
- Early Markers of Alzheimer's Disease: Structural and Functional Brain ChangesTerminatedNCT01867372
- Early Markers of Cognitive Change and Alzheimer s DiseaseCompletedNCT01867346
- Bisnorcymserine in Healthy Adult VolunteersCompletedNCT01747213Phase 1
- Inherited Diseases, Caregiving, and Social NetworksCompletedNCT01498263
- Research on Aging Project in Iceland: Second StageCompletedNCT01322568
- Pioglitazone in Alzheimer DiseaseCompletedNCT00982202Phase 2
- Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and DementiaStatus unknownNCT00966017
- Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down SyndromeStatus unknownNCT00965835
- Screening and Evaluation of Patients With Signs and Symptoms of Alzheimer's DiseaseCompletedNCT00955422
- Evolution of Memory Related ActivityStatus unknownNCT00902499
- Implications of Amyloid PathologyStatus unknownNCT00900770
- Development and Decline of Brain and Cognition Through the Life SpanCompletedNCT00880451
- P-glycoprotein Function in Brain DiseasesCompletedNCT00677885
- Risk Evaluation and Education for Alzheimer's DiseaseCompletedNCT00571025Not applicable
- PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)TerminatedNCT00459693Not applicable
- MRI of Alzheimer's Disease Imaging Amyloid Plaques in Persons With and Without Memory ProblemsCompletedNCT00413621
- PET Imaging of Brain Amyloid Using [11C]MeS-IMPYCompletedNCT00407576Phase 1
- Memory Imaging of Normal AgingCompletedNCT00315575
- MIRAGE: Multi-Institutional Research in Alzheimer's Genetic EpidemiologyCompletedNCT00239759
- BONSAI: Biomarkers of Nonsteroidal Anti-InflammatoriesStatus unknownNCT00239746Phase 1
- Alzheimer's Caregiver Communication StudyCompletedNCT00182988
- PACT: Providers and Alzheimer's Caregivers TogetherCompletedNCT00182897Not applicable
- Anti-Oxidant Treatment of Alzheimer's DiseaseCompletedNCT00117403Phase 1
- Memory Aid for Informed Consent in Alzheimer's ResearchCompletedNCT00105612Not applicable
- Biomarkers and Early Alzheimer's DiseaseStatus unknownNCT00094952
- Predictors of Cognitive Decline in Normal AgingStatus unknownNCT00094939
- PET Changes in Alzheimer's Disease (AD)Status unknownNCT00094913
- Risk Evaluation and Education for Alzheimer's Disease (REVEAL) IICompletedNCT00089882
- Treatment Study of Frontotemporal DementiaCompletedNCT00088751
- Effect of Lithium and Divalproex in Alzheimer's DiseaseCompletedNCT00088387Phase 2
- Huperzine A in Alzheimer's DiseaseCompletedNCT00083590Phase 2
- High Intensity Light Therapy in Alzheimer's DiseaseCompletedNCT00065689Phase 3
- Bathing Persons With Alzheimer's Disease aT Home (The BATH Study)CompletedNCT00062569Not applicable
- VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)CompletedNCT00056225Phase 3
- Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease StudyCompletedNCT00053599Phase 3
- The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's DiseaseCompletedNCT00046358Phase 4
- Brain Imaging in Alzheimer's DiseaseCompletedNCT00039702
- Healthy Aging and Memory StudyCompletedNCT00034567
- Prevention of Cognitive Decline in Alzheimer's Disease by Ingested Interferon AlphaStatus unknownNCT00031018Phase 2
- Evaluation of Age- and Alzheimer's Disease-Related Memory DisorderCompletedNCT00029120
- CATIE-Alzheimer's Disease TrialCompletedNCT00015548Not applicable
- Effectiveness of A Nutritional Brain Metabolic Enhancer for Alzheimer DiseaseCompletedNCT00013923Phase 2
- Effects of an Anti-Inflammatory Drug in Alzheimer's DiseaseCompletedNCT00013650Phase 1
- Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's DiseaseCompletedNCT00006399Phase 2
- Clinical and Genetic Studies of Familial Presenile Dementia With Neuronal Inclusion BodiesCompletedNCT00006176
- A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)CompletedNCT00004845Phase 2/3
- The Effect of Acetylcholine on Memory and AttentionCompletedNCT00001977
- PET Scan of Brain Metabolism in Relation to Age and DiseaseCompletedNCT00001972
- Nefiracetam in the Treatment of Alzheimer's DiseaseCompletedNCT00001933Phase 2
- Brain Imaging in Elderly People and Individuals With Alzheimer's DiseaseCompletedNCT00001917
- Treatment of Alzheimer's Disease With CX516 (Ampalex)CompletedNCT00001662Phase 2
- Diagnosis and Natural History Study of Patients With Neurological ConditionsCompletedNCT00001549
- The Evaluation and Follow-up of Individuals With Memory DisorderCompletedNCT00001480
- Genetic Studies in Alzheimer's DiseaseCompletedNCT00001235
- Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian DisordersTerminatedNCT00001178
- Agitation in Alzheimer's DiseaseCompletedNCT00000179Phase 3
- Multicenter Trial of Prednisone in Alzheimer's DiseaseCompletedNCT00000178Phase 3
- Estrogen Hormone ProtocolCompletedNCT00000177Phase 3
- Alzheimer's Disease Prevention TrialCompletedNCT00000176Phase 3
- Memory Impairment Study (Mild Cognitive Impairment Study)CompletedNCT00000173Phase 3
- Study of Melatonin: Sleep Problems in Alzheimer's DiseaseCompletedNCT00000171Phase 3