National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Diabetes Mellitus trials

The registry lists 82 Diabetes Mellitus studies with National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) as lead sponsor. 8 are open to participants now and 16 have results posted.

Early Phase 1 1Phase 1 5Phase 2 23Phase 3 8Phase 4 4No phase 42(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and AdultsNot yet recruitingNCT07388537
• Effects of Meal Macronutrients on Postprandial LipidsNot yet recruitingNCT07313787Phase 2
• A Natural History Study of Metabolic Sizing in Health and DiseaseRecruitingNCT05398783
• Early Tracking of Childhood Health Determinants (ETCHED) StudyRecruitingNCT03481829
• New Heart Imaging Techniques to Evaluate Possible Heart DiseaseRecruitingNCT01399385Not applicable
• Urinary Vitamin C Loss in Diabetic SubjectsRecruitingNCT00071526
• Genetic Studies of Insulin and DiabetesRecruitingNCT00001987
• Diabetes and Heart Disease Risk in BlacksRecruitingNCT00001853
• Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)CompletedNCT04209075Phase 2Results posted
• Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes MellitusTerminatedNCT03428945Phase 2Results posted
• Title: Therapeutic Targets in African-American Youth With Type 2 DiabetesCompletedNCT02960659Phase 1/2Results posted
• ATG-GCSF in New Onset Type 1 DiabetesCompletedNCT02215200Phase 2Results posted
• CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1CompletedNCT01773707Phase 2Results posted
• Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"CompletedNCT01030861Phase 2Results posted
• Canakinumab Study in Individuals With Newly Diagnosed Type 1 DiabetesCompletedNCT00947427Phase 2Results posted
• Novel Therapy to Preserve Beta Cell Function in New Onset Type 1 DiabetesTerminatedNCT00837759Phase 2Results posted
• Effects of Recombinant Human Glutamic Acid Decarboxylase on the Progression of Type 1 Diabetes in New Onset SubjectsCompletedNCT00529399Phase 2Results posted
• Intravenous CTLA4-lg Treatment in Recent Onset Type 1 Diabetes MellitusCompletedNCT00505375Phase 2Results posted
• Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes MellitusCompletedNCT00419562Phase 3Results posted
• The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy VolunteersCompletedNCT00339833Phase 4Results posted
• Rituximab in New Onset Type 1 DiabetesCompletedNCT00279305Phase 2Results posted
• New Onset of Type 1 Diabetes Mycophenolate Mofetil-Daclizumab Clinical TrialCompletedNCT00100178Phase 2Results posted
• Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)CompletedNCT00081328Phase 3Results posted
• Diabetes Prevention Program Outcomes StudyCompletedNCT00038727Phase 3Results posted
• People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral AgentsActive, not recruitingNCT03520660Phase 4
• Methyldopa for Reduction of DQ8 Antigen Presentation in At-Risk Subjects for Type 1 DiabetesWithdrawnNCT03396484Phase 2
• Compassionate Use of Metreleptin in Previously Treated People With Generalized LipodystrophyActive, not recruitingNCT02262832Phase 3
• Compassionate Use of Metreleptin in Previously Treated People With Partial LipodystrophyActive, not recruitingNCT02262806Phase 2
• Identifying Risk for Diabetes and Heart Disease in WomenCompletedNCT01809288
• Healthy Lifestyle in PregnancyWithdrawnNCT01585454
• TODAY2 Phase 1 Immediate Post-Intervention Observational Follow-up StudyCompletedNCT01364350
• Type 2 Diabetes and Obesity in Mexican Pimas: Gene-Environment InteractionCompletedNCT01168297
• Molecular and Clinical Profile of Diabetes Mellitus and Its ComplicationsSuspendedNCT01105858
• Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes MellitusTerminatedNCT01083108Phase 2
• Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy StudyCompletedNCT01007266Phase 2
• Natural History of Autoimmune Diabetes and Its ComplicationsTerminatedNCT00896610
• Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese WomenCompletedNCT00862433Phase 1
• Community Health Workers in Diabetes Care in American SamoaCompletedNCT00850824Not applicable
• Adolescent Self-Management of Type 1 Diabetes: an Intervention (Completed)CompletedNCT00848705Early Phase 1
• Parental Management of Young Children's DiabetesCompletedNCT00847327Not applicable
• Assessment of Beta Cell Mass by PET Scans With [11C] Dihydrotetrabenazine (DTBZ) in Longstanding Type 1 Diabetes.CompletedNCT00738907
• A Trial of Two Diets for Weight and Diabetes ManagementCompletedNCT00729196Not applicable
• Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in YouthCompletedNCT00693511Not applicable
• Effect of Physical Activity on Metabolic Syndrome in Pregnancy & Fetal OutcomeCompletedNCT00647595Phase 3
• Computer Based Intervention for Type 2 Diabetes in YouthCompletedNCT00570466Not applicable
• Middle-School Based Primary Prevention Trial of Type 2 DiabetesCompletedNCT00458029Not applicable
• Preventing Depression Recurrence in DiabetesCompletedNCT00374426Phase 4
• Assessment of Beta Cell Mass in Type 1 Diabetes With 11C-Dihydrotetrabenazine and PET ScanCompletedNCT00351650
• Family Investigation of Nephropathy and Diabetes (F.I.N.D.)Active, not recruitingNCT00342927
• Prospective Studies of the Natural History of Diabetes Mellitus and Its Complications in the Gila River Indian CommunityCompletedNCT00339482
• Food Intake and Appetite in the Children of Mothers With DiabetesCompletedNCT00339313
• Nutritional Intervention to Prevent DiabetesCompletedNCT00333554Not applicable
• The Family Investigation of Nephropathy and Diabetes StudyCompletedNCT00301249
• The Diabetes TeleCare StudyCompletedNCT00288132Not applicable
• A Self-care Intervention for Latino Adults With DiabetesCompletedNCT00263835Phase 2
• Use of Midlevel Providers in Diabetes ManagementCompletedNCT00237094Not applicable
• Iron Depletion Therapy for Type 2 DM and NAFLDCompletedNCT00230087Not applicable
• T Cell Validation Study Using Blood Samples From Subjects With Recent Onset Type 1 Diabetes MellitusCompletedNCT00212329
• Exercise Training in Type 2 Diabetes and HypertensionCompletedNCT00212303Phase 4
• Breaking Down Barriers to Diabetes Self-CareCompletedNCT00142922Not applicable
• Evaluation of Diabetes Self-Management Consultant CareCompletedNCT00109720Not applicable
• Vermont Diabetes Information SystemCompletedNCT00109369Not applicable
• Improving Diabetes in Primary Care (IMPACT)CompletedNCT00108927
• Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical TrialsCompletedNCT00105352Not applicable
• Islet Transplantation for Patients With Type 1 DiabetesCompletedNCT00073281Phase 1
• Prevention of Type 2 Diabetes Mellitus in ChildrenCompletedNCT00073268Phase 1
• Safety and Pharmacokinetics (PK) of hOKT3g1 (Ala-Ala) in Type 1 Diabetes Mellitus (T1DM)CompletedNCT00073255Phase 1
• Diabetes Therapy to Improve BMI and Lung Function in CFCompletedNCT00072904Phase 3
• Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 DiabetesCompletedNCT00065676Phase 2
• Type 2 Diabetes Primary Prevention for At Risk GirlsCompletedNCT00063674Not applicable
• Randomized Trial of Health Events Costs in Diabetic BlacksCompletedNCT00022750Not applicable
• Islet Cell Transplantation Alone and CD34+ Enriched Bone Marrow Cell Infusion in Patients With Diabetes Mellitus: Steroid-Free RegimenCompletedNCT00021801Phase 2
• Islet Cell Transplantation Alone in Patients With Type I Diabetes Mellitus: Steroid-free ImmunosuppressionCompletedNCT00021788Phase 2
• NEW DAY: Nutrition, Exercise, Weight Loss, Diabetes And YouCompletedNCT00007800Phase 2
• Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing ImmunosuppressionCompletedNCT00006505Phase 2
• Native Hawaiian Diabetes Intervention ProgramCompletedNCT00006165Not applicable
• Family-Centered Diabetes ProjectCompletedNCT00006159Not applicable
• Diabetes Prevention ProgramCompletedNCT00004992Phase 3
• The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1)CompletedNCT00004984Phase 3
• Education and Group Support for Diabetic HispanicsCompletedNCT00004983Not applicable
• Genetic Influence on Susceptibility to Type 1 Diabetes MellitusCompletedNCT00001985
• Diagnosis and Treatment of Patients With Cystic FibrosisTerminatedNCT00001223