Mario Negri Institute for Pharmacological Research: all 159 studies

Page 1 of 2. Open to participants first (36), then studies with results posted, then the rest; newest registration first within each.

• Premedication With Dexamethasone for Preventing Interstitial Lung Disease in Patients With Breast Cancer Treated With Trastuzumab DeruxtecanNot yet recruitingNCT07828054Phase 3
• Implementation of New Models of Ovarian Carcinoma Resistant to TherapyNot yet recruitingNCT07757711
• Trauma Molecular ProcessesRecruitingNCT07683169
• Thyroid Hormones in CKDNot yet recruitingNCT07663773
• Emergency and Urgent Care Indicators in PiedmontNot yet recruitingNCT07606209
• Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and SenescenceNot yet recruitingNCT07596615Not applicable
• Pragmatic Study to Optimize Neoadjuvant Treatment and Surgical De-escalation in HR+/HER2- Early Breast Cancer Using Oncotype DX and AbemaciclibNot yet recruitingNCT07428018Phase 2
• Omics of Rituximab-resistanceNot yet recruitingNCT07416942
• RESOLving INflammation Through Diet for Health (RESOLVIN)RecruitingNCT07331103Not applicable
• AVF-MONITOR POC Proof-of-concept StudyNot yet recruitingNCT07318025Not applicable
• Mechanisms Underlying SGLT2i Kidney Effect in DKD ProgressionNot yet recruitingNCT07270198Not applicable
• Obinutuzumab in Adult Rituximab-Dependent Nephrotic SyndromeNot yet recruitingNCT07233330Phase 2
• Mild TBI in the Emergency DepartmentRecruitingNCT07021118
• Reproducibility of Multiparametric Renal Magnetic Resonance Imaging on 1.5T MRI ScannersRecruitingNCT06884410Not applicable
• Patiromer and Diet/hrQoL in Chronic DialysisRecruitingNCT06858280Phase 3
• Evaluation of the Quality of Care in the Emergency Department by Studying the Appropriateness of HospitalizationsRecruitingNCT06846879
• New Advanced Vascular Imaging Ultrasound ProtocolsRecruitingNCT06841887
• Phase II Study of Radiotherapy Followed by Durvalumab and Ceralasertib in Stage III NSCLC Patients With Thoracic Relapses +/- Oligometastases After PACIFIC RegimenRecruitingNCT06680050Phase 2
• Blood Flow Conditions and Sounds in AVFsRecruitingNCT06411353Not applicable
• Kidney Perfusion With or Without AbsorptionRecruitingNCT06374121Not applicable
• Development of a Multipurpose Dashboard to Monitor the Situation of Emergency DepartmentsRecruitingNCT06372379
• Propensity to Hospitalize Patients From the ED in European Centers.RecruitingNCT06354764
• Autoantibodies Against-nephrin in Idiopathic Nephrotic SyndromeRecruitingNCT06334692
• An Outcome Analysis of Primary Membranous NephropathyRecruitingNCT06242327
• Development of a Natural Language Processing Tool to Enable Clinical Research in Emergency MedicineRecruitingNCT06240572
• Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALSRecruitingNCT06126315Phase 2/3
• Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare DiseasesRecruitingNCT05996731Not applicable
• Reduction Of Dietary Salt Intake To Control Systolic Blood Pressure In Hypertensive Older PatientsNot yet recruitingNCT05976477Not applicable
• Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized TherapyRecruitingNCT05805202Not applicable
• Acoustic Analysis of VA SoundsRecruitingNCT05612022
• CardioPulmonary Resuscitation With Argon (CPAr) TrialRecruitingNCT05482945Phase 2
• Severe Acquired Brain Injuries: Prognostic Factors and Quality of CareRecruitingNCT04905264
• Health-care Quality in Semi-intensive Care UnitsRecruitingNCT04676347
• Autoreactive B Cells in Membranous NephropathyRecruitingNCT04095156
• Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Gastric Carcinoma.GOETH StudyRecruitingNCT03917173Not applicable
• Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study.RecruitingNCT03914820Not applicable
• Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW)CompletedNCT03689114Phase 4Results posted
• The Effect of RNS60 on ALS BiomarkersCompletedNCT03456882Phase 2Results posted
• Best Approach in Recurrent-Ovarian-Cancer-with Cediranib-OlaparibCompletedNCT03314740Phase 2Results posted
• Decision-aid on Breast Cancer ScreeningCompletedNCT03097653Not applicableResults posted
• The TackSHS Survey: a Pan-European Study on SHSCompletedNCT02928536Results posted
• RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder.CompletedNCT01809106Phase 4Results posted
• A New Crowding Indicator in the Emergency DepartmentActive, not recruitingNCT07111624
• Simulated and Synthetic Health Data: Improving Clinical Research on Rare Diseases. A Real-World Data Simulation of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Trials. A Retrospective, Observational StudyActive, not recruitingNCT07016282
• Effect of B-cell Depleting Therapies on PLA2R-specific B Cells in Patients With Membranous NephropathyCompletedNCT06994468Not applicable
• Comparing the Performance of Serum Creatinine and Cystatin C-based GFR Estimations in Predicting Directly Measured GFR in Patients With or Without Nephrotic SyndromeActive, not recruitingNCT06797609
• Artificial Intelligence-based Techniques to Characterize KIdney Microstructure on Histological ImagEsActive, not recruitingNCT06690190
• Artificial Intelligence-based Image Processing Methods to Advance the Characterization of Polycystic Kidney DiseaseActive, not recruitingNCT06688981
• A Possible Founding PKD2 Mutation Associated With Variable Phenotypes of ADPKD in Bergamo ProvinceCompletedNCT06594367
• 1 vs 7 RATG Infusions in Renal TransplantationActive, not recruitingNCT06374095
• Medical Images Collection ResearchActive, not recruitingNCT06354829
• Evaluation of the Quality of Care in the Emergency Department by Studying the Appropriateness of Admissions of Patients Accessing the Emergency Department (ASST Papa Giovanni XXIII)Active, not recruitingNCT06345378
• Evaluation of the Quality of Care in the Emergency Department by Studying the Appropriateness of Admissions of Patients Accessing the Emergency Department (Fondazione IRCCS Ca' Granda Ospedale Maggione Policlinico)Active, not recruitingNCT06345352
• Outcome of ADPKD With Octreotide LARActive, not recruitingNCT06193616
• First Line Treatment With Olaparib in Combination With Bevacizumab in HRD Positive PatientsActive, not recruitingNCT06121401Phase 4
• New Analytic Tools for aHUS and C3G DiagnosisActive, not recruitingNCT05985122Not applicable
• MuLtidimensional School-based and Family interVentions to Promote hEalthy and Sustainable LifestYle for the ChildhoodCompletedNCT05966051
• LSCI and Thermography in Diabetic Foot Patients Affected by Ulcer(s): (MY-FOOT-B)WithdrawnNCT05791929
• Patiromer Trial in CKD Stage IIIB to VTerminatedNCT05786469Phase 3
• A Prevention Trial of Canakinumab in Subjects at High Risk for Lung CancerTerminatedNCT05725343Phase 3
• B Cells in Idiopathic Nephrotic SyndromeCompletedNCT05712369Not applicable
• Thyroid Hormones in ADPKDCompletedNCT05646420Not applicable
• COVID-19 Algorithm Treatment at HomeWithdrawnNCT05413642Phase 3
• Anti-inflammatory Drug Algorithm for COVID-19 Home TreatmentWithdrawnNCT05249790Phase 3
• Multiparametric MRI in Healthy Volunteers and CKD PatientsActive, not recruitingNCT05229263Not applicable
• Obinutuzumab in Primary MNCompletedNCT05050214Phase 2
• MOR202 for Refractory MNCompletedNCT04893096Phase 2
• The European Tinnitus Survey: a Study on Tinnitus Prevalence in 12 European CountriesCompletedNCT04892095
• A Simple Approach to Prevent Hospitalization for COVID-19 PatientsCompletedNCT04854824
• Familiar Fatal Insomnia: Preventive Treatment With Doxycycline in Subject With Disease RiskCompletedNCT04846335Phase 2
• Genotype and Susceptibility to COVID-19Active, not recruitingNCT04799834
• A Simple Approach to Treat COVID-19 Patients at Home.CompletedNCT04794998
• Dapagliflozin in Non-diabetic Stage IV CKDCompletedNCT04794517Phase 2
• Study on Trabectedin in Combination With Pioglitazone in Patients Myxoid Liposarcomas With Stable Disease After T Alone.CompletedNCT04794127Phase 2
• Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLCTerminatedNCT04765709Phase 2
• COVID-19 Impact on the Lombardy Region's Emergency SystemCompletedNCT04669925
• Proton Pump Inhibitors (PPI): a Study to Improve Appropriate Prescriptions in the ElderlyCompletedNCT04637750Not applicable
• Home Care for Patients With COVID-19: Active Monitoring in Two Italian Health Units (Casale Monferrato and Torino)TerminatedNCT04361916Not applicable
• Early CPAP in COVID-19 Patients With Respiratory Failure.CompletedNCT04326075Not applicable
• Early CPAP in COVID-19 Patients With Respiratory Failure. A Prospective Cohort Study.CompletedNCT04323878
• SGLT2 Inhibitors in Glomerular HyperfiltrationWithdrawnNCT04143581Phase 2
• VasQ and Hemodynamic Conditions in AVFsCompletedNCT04141852Not applicable
• Diadem to Investigate the Activity and Safety of DurvalumabCompletedNCT04115111Phase 2
• Evaluation of ATRA Activity in Combination With Anastrozole in Pre-operative Phase of Operable Early Breast CancerTerminatedNCT04113863Phase 2
• Eculizumab to Cemdisiran Switch in aHUSWithdrawnNCT03999840Phase 2
• Selection of People at Low Cardiovascular Risk: Development of an Inexpensive Pre-screening Algorithm Using Only Non-laboratory Measures. The SKIM Risk Study.CompletedNCT03962309
• Peripheral Artery Disease in Patients With Stable Coronary Artery Disease in General Practice: Prevalence, Management and Clinical Outcomes.CompletedNCT03921905
• NASCITA Italian Birth Cohort StudyActive, not recruitingNCT03894566
• Newton Study (NEW Dosing MainTenance Therapy Ovarian CaNcer)TerminatedNCT03891576Phase 2
• Non-contrast Enhanced MRI in Patients With C3 Glomerulopathy (C3G) or Immune-complex Membranoproliferative Glomerulonephritis (IC-MPGN) Enrolled in the ACH471-205 StudyCompletedNCT03723512Not applicable
• Insulin Treatment in Diabetic Older People With Heart Failure.TerminatedNCT03665350Phase 2
• CoQun Study - (COQUN): a Study to Evaluate the Effects of CoQun in Patients Affected by Open-angle GlaucomaTerminatedNCT03611530Not applicable
• Atezolizumab Trial in Endometrial Cancer - AtTEndCompletedNCT03603184Phase 3
• Treat_CCM: Propranolol in Familial Cerebral Cavernous MalformationCompletedNCT03589014Phase 2
• Tolvaptan-Octreotide LAR Combination in ADPKDCompletedNCT03541447Phase 2
• Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast CancerCompletedNCT03358017Phase 2
• the Role of Two Different Metronomic Chemotherapy Regimens in Locally Advanced or Metastatic Triple Negative Breast Cancer Patients (TNBC) as Maintenance Therapy After First Line TreatmentTerminatedNCT03358004Phase 2
• Real Time Amplitude Spectrum Area to Guide DefibrillationTerminatedNCT03237910Not applicable
• E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AFCompletedNCT03188211Not applicable
• Rheumatoid Arthritis Treatment After First Anti-TNF INvestiGationTerminatedNCT03100253Phase 4

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