M.D. Anderson Cancer Center: Lung Neoplasms trials

The registry lists 149 Lung Neoplasms studies with M.D. Anderson Cancer Center as lead sponsor. 22 are open to participants now and 38 have results posted.

Early Phase 1 1Phase 1 37Phase 2 71Phase 3 5No phase 55(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Dissemination Of Lung Cancer Screening Education Through Tobacco QuitlinesNot yet recruitingNCT07720141Not applicable
• Adaptation and Pilot Testing of a Lung Cancer Screening Decision Aid for Patients From a Safety-Net Healthcare SystemRecruitingNCT07382557Not applicable
• Registry Trial and Needs Assessment of Patients With Young-onset Lung Cancer: Impact of a Dedicated Care Program on Patient Experience and OutcomesRecruitingNCT07220096
• Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigating Radiation-response and ToxicityRecruitingNCT06909201
• CPRIT: Patient Adherence to Lung Cancer ScreeningRecruitingNCT06872723
• Novel INPUT Screening Tool to Improve Illness Understanding in Patients With Metastatic or Incurable Lung CancerRecruitingNCT06743308Not applicable
• Goals of Care Discussion for Patients With Advanced Lung and Gastrointestinal Cancer in the Emergency Department of a Comprehensive Cancer CenterRecruitingNCT06420206Not applicable
• REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)RecruitingNCT05632809Phase 2
• PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target IdentificationRecruitingNCT05049837
• Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized ChemoradiationRecruitingNCT05010109Not applicable
• Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 TherapyRecruitingNCT04892953Phase 2
• Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung TrialRecruitingNCT04789681Phase 2
• Walking After Surgery to Improve Recovery and Outcomes After Surgery, AIRTECH StudyRecruitingNCT04783168Not applicable
• Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid TumorsRecruitingNCT04771520Phase 2
• The Rise in Robotic Atypical SegmentectomiesRecruitingNCT04644952
• Educating Smokers About Lung Cancer Screening Using Tobacco QuitlinesRecruitingNCT04595422Not applicable
• Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer PatientsRecruitingNCT04038619Phase 1
• Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their CaregiversRecruitingNCT03948100Not applicable
• Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With CancerRecruitingNCT03819296Phase 1
• Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung CancerRecruitingNCT03422302Not applicable
• Couple-Based Meditation for Metastatic Lung Cancer Patients and Their PartnersRecruitingNCT02596490Not applicable
• Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton TherapyRecruitingNCT00991094
• Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung CancerActive, not recruitingNCT05144542Not applicableResults posted
• Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung CancerTerminatedNCT04971187Phase 2Results posted
• Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted AntibodiesTerminatedNCT04902040Phase 1/2Results posted
• Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain MetastasesTerminatedNCT04789668Phase 1/2Results posted
• Bintrafusp Alfa Before Surgery for the Treatment of Untreated Resectable Non-small Cell Lung CancerTerminatedNCT04560686Phase 2Results posted
• Bronchoscopic Laser Ablation of Peripheral Lung TumorsTerminatedNCT03707925Not applicableResults posted
• Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung StudyCompletedNCT03634241Phase 2Results posted
• Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung CancerCompletedNCT03581487Phase 1/2Results posted
• Lung Cancer STARS Trial - STARS Revised Clinical Trial Protocol: Stereotactic Ablative Radiotherapy (SABR) in Stage I Non-small Cell Lung Cancer Patients Who Can Undergo LobectomyCompletedNCT02357992Not applicableResults posted
• A Phase I/II Study of Ibrutinib in Previously Treated Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung CancerCompletedNCT02321540Phase 1/2Results posted
• PCORI-CER-1306-03385 Informed Decisions About Lung Cancer ScreeningCompletedNCT02286713Not applicableResults posted
• Metformin in Non Small Cell Lung Cancer (NSCLC)TerminatedNCT02285855Phase 2Results posted
• The ATTAIN Study: A Therapeutic Trial of Afatinib In the Neoadjuvant SettingTerminatedNCT02271906Phase 2Results posted
• Surgery and/or Radiation Therapy or Standard Therapy and/or Clinical Observation in Treating Patients With Previously Treated Stage IV Non-small Cell Lung CancerCompletedNCT01725165Phase 2Results posted
• Minocycline Study in Non Small Cell Lung Cancer (NSCLC) Patients for Chemoradiation TherapyCompletedNCT01636934Phase 2Results posted
• Stereotactic Body Radiotherapy (SBRT) Versus Stereotactic Body Proton Therapy (SBPT)TerminatedNCT01511081Phase 2Results posted
• A Study for Reducing Symptom Burden Produced by Chemoradiation Treatment for Non Small Cell Lung Cancer by Minocycline and ArmodafinilCompletedNCT01317550Not applicableResults posted
• BATTLE-FL: Front-Line Biomarker-Integrated Treatment Study in Non Small Cell Lung CancerCompletedNCT01263782Phase 2Results posted
• Fish Oil Versus Statins Versus Placebos in Reducing Atrial Fibrillation in Patients Undergoing Thoracic Surgery for Lung CancerTerminatedNCT01259284Phase 2/3Results posted
• BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung CancerCompletedNCT01248247Phase 2Results posted
• Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional RecurrenceCompletedNCT00915005Phase 2Results posted
• Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung CancerCompletedNCT00871923Phase 2Results posted
• Dasatinib and Erlotinib in Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00826449Phase 1/2Results posted
• TARCEVA (Erlotinib) in Combination With Chemoradiation in Patients With Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00563784Phase 2Results posted
• Celecoxib as Adjuvant Biologic Therapy in Patients With Head and Neck and Lung CancerTerminatedNCT00527982Phase 2Results posted
• Evaluation of the Bio-Seal Biopsy Track PlugCompletedNCT00527722Phase 2/3Results posted
• Single Agent Alimta in Poor Performance Status in Non-small Cell Lung CancerCompletedNCT00508144Phase 2Results posted
• Concurrent Proton and Chemotherapy in Locally Advanced Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00495170Phase 2Results posted
• Proton Radiotherapy for Patients With Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00495040Phase 2Results posted
• Interactive Voice Response (IVR) Symptom Assessment in Non-Small Cell Lung Cancer (NSCLC) PatientsCompletedNCT00423436Not applicableResults posted
• BATTLE Program: Sorafenib in Patients With NSCLCCompletedNCT00411671Phase 2Results posted
• BATTLE Program: Tarceva and Targretin in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00411632Phase 2Results posted
• BATTLE Program: ZD6474 in Previously Treated Subjects With NSCLCCompletedNCT00410189Phase 2Results posted
• BATTLE Program: Erlotinib in Previously Treated Subjects With Advanced NSCLCCompletedNCT00410059Phase 2Results posted
• Malignant Pleural Effusion With ZD6474TerminatedNCT00402896Phase 2Results posted
• Phase II Study of ZD6474 in Advanced NSCLCTerminatedNCT00290537Phase 2Results posted
• Avastin/Docetaxel/Carboplatin in Non-Small Cell Lung CancerCompletedNCT00271505Phase 2Results posted
• Tarceva Surgery for Resectable Stage IIIA(N2) and IIIB (T4 N2) Non-Small-Cell Lung CancerTerminatedNCT00063258Phase 2Results posted
• Brigatinib Plus Chemotherapy or Local Consolidation Therapy in ALK Positive Advanced Non-small Cell Lung Cancer (BrightStar-2)WithdrawnNCT06522360Phase 2
• A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid TumorsActive, not recruitingNCT06237881Phase 1/2
• Reminder Messages for Lung Cancer ScreeningActive, not recruitingNCT05952778
• A Phase I Study of Adagrasib and Durvalumab for Treatment of Advanced Non-small Cell Lung Cancers and Gastro-intestinal Cancers Harboring KRAS G12C MutationsWithdrawnNCT05848843Phase 1
• A Phase Ib Study to Evaluate the Safety and Preliminary Efficacy of IL6-receptor Antibody Sarilumab in Combination With antiPD1 Antibody Cemiplimab for Patients With Non-small Cell Lung Cancer.Active, not recruitingNCT05704634Phase 1
• Feasibility, Safety, and Efficacy of Stereotactic MRI-Guided Adaptive Radiation Therapy (SMART) for Central Lung TumorsTerminatedNCT05609331Not applicable
• A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C MutationActive, not recruitingNCT05118854Phase 2
• Three-Dimensional Fluoroscopic Guidance During Transbronchial CryobiopsyCompletedNCT05059691
• Feasibility Study of Anatomical Modeling for Image Guided Thoracic SurgeryCompletedNCT05046067Not applicable
• Poziotinib and Ramucirumab for the Treatment of EGFR Exon 20 Mutant Stage IV Non-small Cell Lung CancerWithdrawnNCT05045404Phase 2
• Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME StudyWithdrawnNCT05022394Phase 1/2
• Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung CancerCompletedNCT05017025Phase 1/2
• Feasibility of Mobile-CT-Assisted Bronchoscopy for the Diagnosis of Lung LesionCompletedNCT04995172
• Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING StudyWithdrawnNCT04987281Phase 2
• Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial CarcinomaActive, not recruitingNCT04940299Phase 2
• Ensartinib, Carboplatin, Pemetrexed and Bevacizumab for the Treatment of Stage IIIC or IV or Recurrent ALK-Positive Non-small Cell Lung CancerActive, not recruitingNCT04837716Phase 1
• Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid MalignanciesTerminatedNCT04785287Phase 1/2
• Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO TrialActive, not recruitingNCT04728230Phase 1/2
• Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine CarcinomasActive, not recruitingNCT04701307Phase 2
• Yoga Program for Improving the Quality of Life in Couples Coping With CancerActive, not recruitingNCT04607590Not applicable
• Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain MetastasisActive, not recruitingNCT04516070Phase 2
• NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung CancerActive, not recruitingNCT04505267Phase 1
• Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung CancerCompletedNCT04479306Phase 1
• Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME StudyActive, not recruitingNCT04430725
• Centralized Lung Cancer EARly Detection Among Smokers (CLEAR Study)Active, not recruitingNCT04200534Early Phase 1
• Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung CancerActive, not recruitingNCT04013542Phase 1
• Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing TreatmentActive, not recruitingNCT03731585Not applicable
• Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung CancerActive, not recruitingNCT03707938Phase 1
• Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung CancerActive, not recruitingNCT03637816Phase 2/3
• Radial-Probe Endobronchial Ultrasound in Detecting Atelectasis in Patients Undergoing Peripheral BronchoscopyCompletedNCT03523689
• Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR StudyActive, not recruitingNCT03410043Phase 2
• Nivolumab and Ipilimumab With or Without Local Consolidation Therapy in Treating Patients With Stage IV Non-Small Cell Lung CancerActive, not recruitingNCT03391869Phase 3
• Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally AdvancedActive, not recruitingNCT03225664Phase 1/2
• Stereotactic Body Radiation Therapy With or Without Nivolumab in Treating Patients With Stage I-IIA or Recurrent Non-small Cell Lung CancerActive, not recruitingNCT03110978Phase 2
• Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal DiseaseActive, not recruitingNCT03025256Phase 1
• MEDI4736 With Selumetinib for KRAS Mutant Non-Small Cell Lung Cancer (NSCLC)WithdrawnNCT03004105Phase 2
• Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal CancerActive, not recruitingNCT02983578Phase 2
• Study of Ibrutinib Followed by Ibrutinib in Combination With Nivolumab in Non-Small Cell Lung Cancer (NSCLC)WithdrawnNCT02950038Phase 2
• EBUS TBNA After PET/CT in Diagnosing Patients With Stage I-IIA Non-small Cell Lung Cancer Evaluated for Stereotactic Body Radiation TherapyCompletedNCT02719847
• MPDL3280A With Chemoradiation for Lung CancerActive, not recruitingNCT02525757Phase 2